ABSTRACT
@#<p><strong>OBJECTIVE:?</strong> This study aimed to determine the prevalence of nasopharyngeal tuberculosis among patients who were initially assessed to have a nasopharyngeal mass and subsequently underwent biopsy in a Philippine Tertiary General Hospital from 2013 to 2015.</p><p><strong> </strong></p><p><strong>METHODS:</strong>?</p><p><strong>Design</strong>: Case Series</p><p><strong>Setting</strong>: Tertiary National University Hospital</p><p><strong>Participants</strong>: All patients with nasopharyngeal mass identified from January 2013 to December 2015 from a hospital wide census who underwent biopsy were investigated using chart and histopathology review. The prevalence of tuberculosis, malignancies and other findings were determined.</p><p><strong> </strong></p><p><strong>RESULTS</strong>:? Among 285 nasopharyngeal biopsies done between 2013 and 2015, 33 (11.6%) were histologically compatible with nasopharyngeal tuberculosis, 177 (62.1%) were different types of nasopharyngeal carcinoma, 59 (20.7%) were chronic inflammation, 4 (1.4%) were lymphoma, 5 (1.8%) were normal, and 7 (2.5 %) had diagnoses other than those above.</p><p><strong> </strong></p><p><strong>CONCLUSION:</strong> This study suggests a relatively high prevalence rate (11.6%) of nasopharyngeal tuberculosis in patients who have a nasopharyngeal mass. This indicates that nasopharyngeal tuberculosis should always be a differential when confronted with a mass in the nasopharynx especially in tuberculosis endemic areas.</p><p> </p><p><strong>KEYWORDS:</strong> nasopharyngeal tuberculosis; prevalence; censuses; tertiary care centers; Philippines; carcinoma; nasopharynx; biopsy; tuberculosis; lymphoma </p><p> </p>
Subject(s)
Humans , Male , Female , Prevalence , Censuses , Tertiary Care Centers , Philippines , Nasopharynx , Biopsy , Tuberculosis , Lymphoma , CarcinomaABSTRACT
Objectiv@#This study aimed to determine the prevalence of nasopharyngeal tuberculosis among patients who were initially assessed to have a nasopharyngeal mass and subsequently underwent biopsy in a Philippine Tertiary General Hospital from 2013 to 2015. @*Methods@#Design: Case Series. Setting: Tertiary National University Hospital. Participants: All patients with nasopharyngeal mass identified from January 2013 to December 2015 from a hospital wide census who underwent biopsy were investigated using chart and histopathology review. The prevalence of tuberculosis, malignancies and other findings were determined.@*Results@#Among 285 nasopharyngeal biopsies done between 2013 and 2015, 33 (11.6%) were histologically compatible with nasopharyngeal tuberculosis, 177 (62.1%) were different types of nasopharyngeal carcinoma, 59 (20.7%) were chronic inflammation, 4 (1.4%) were lymphoma, 5 (1.8%) were normal, and 7 (2.5 %) had diagnoses other than those above. @*Conclusion@#This study suggests a relatively high prevalence rate (11.6%) of nasopharyngeal tuberculosis in patients who have a nasopharyngeal mass. This indicates that nasopharyngeal tuberculosis should always be a differential when confronted with a mass in the nasopharynx especially in tuberculosis endemic areas.
Subject(s)
Prevalence , Censuses , Tertiary Care Centers , Philippines , Carcinoma , Nasopharynx , Biopsy , Tuberculosis , LymphomaABSTRACT
Tuberculous infection of the upper respiratory tract is an uncommon clinical condition and in that nasopharyngeal involvement is struck with rarity per se. This condition is often prevalent in people of low socioeconomic strata living in endemic areas, especially in developing countries. It has a silent and indolent course and most commonly mimicks nasopharyngeal carcinoma in its clinical presentation. In absence of concurrent pulmonary involvement, it is often misdiagnosed or diagnosed only after the biopsy has been taken. Nevertheless, high index of suspicion is required on part of the clinician to diagnose this comparatively rare entity.
Subject(s)
Antitubercular Agents/therapeutic use , Adult , Bacillus , HIV , Humans , Male , Nasopharyngeal Diseases/diagnosis , Nasopharyngeal Diseases/drug therapy , Nasopharyngeal Diseases/microbiology , Nasopharynx/microbiology , Nasopharynx/pathology , Staining and Labeling , Tuberculosis/diagnosis , Tuberculosis/drug therapy , Tuberculosis/microbiologyABSTRACT
It is well known that F-18 FDG PET/CT is a highly sensitive diagnostic modality for cancer patients. However, false positive cases resulting from benign disease such as tuberculosis in the endemic area often compromise the diagnostic accuracy of F-18 FDG PET/CT. Nasopharyngeal tuberculosis is a rare disease although extrapulmonary tuberculosis can involve any region in the body. We report one case of nasopharyngeal tuberculosis incidentally detected on F-18 FDG PET/CT.