ABSTRACT
Diabetes has been an epidemic in China. Developing economic levels, changes in diet, increasing of obesity, aging, and other factors are thought to be the main contributors. In the new situation for preventing and managing diabetes, several key issues should be seriously considered. We need to carry out high quality multi-center clinical researches based on a well-established nationwide collaborative research network; to identify and validate novel, sensitive and reliable diabetes risk factors and predictors using the new data collection system, and the omics technology based on the large-scale prospective cohorts with a long-term follow up; to reclassify diabetes based on the molecular and functional annotation, and finally to in-depth understand and update the pathogenesis of the disease. Furthermore, using the artificial intelligence and other advanced technologies combined with big medical and research data, etc., we should build new types of diabetes prediction models and systems, as well as machine-assisted diagnosis and treatment systems. Finally, we should carry out translational researches, as well as to develop early detection technologies and clinical pathways suitable for all levels of medical institutions.