ABSTRACT
Atractylodes macrocephala Koidz. is a commonly used Chinese materia medica in clinical treatment, and its chemical constituents mainly include volatile oil, lactones, glycosides, atractylodes polysaccharide, and amino acids. In addition to the pharmacological effects of anti-aging, anti-inflammatory, anti-tumor, regulating gastrointestinal function, and liver protection, A. macrocephala also has the function of treating and improving many kinds of diseases in nervous-mental system. In this paper, the role of A. macrocephala in nervous-mental system and its research mechanisms were summarized by literature analysis, in order to provide a reference for further explaining the mechanism and clinical medication of A. macrocephala in nervous-mental system.