Halo Dermatitis Around a Compound Nevus / 대한피부과학회지

Halo dermatitis was first described as a halo-shaped eczematous change around a nevocellular nevus. However, other cases developed around various kinds of lesions including seborrheic keratosis or lentigo were reported later on, so it is now considered not to be specific for melanocytes or nevus cells. It has never been reported to be associated with regression of central lesion, in contrast to halo nevus. We report a case of halo dermatitis developed around a compound nevus in a 20-year-old male patient. On histopathologic examination, the central lesion was a compound nevus and the surrounding lesion was consistent with chronic eczematous dermatitis.

Multiple Adnexal Neoplasms Arising from Nevus Sebaceous / 대한피부과학회지

Nevus sebaceous is a tumor of primary epithelial germ cells that is generally first noticed at birth. Clinically, there is a yellowish waxy plaque with overlying alopecia on the scalp. Less commonly, it can be seen on the face, trunk, and extremities. Syringocystadenoma papilliferum is the most common benign growth from nevus sebaceous, whereas basal cell carcinoma is the most frequent malignancy. The proportion of the malignant tumors occurring on nevus sebaceous is highly variable according to the published series, and there are controversies on the nature of these neoplasms. We experienced a rare case of nevus sebaceous, superimposed of 5 multiple type tumors at the comparatively young age: syringocystadenoma papilliferum, basal cell carcinoma, nevocellular nevus, sebaceous adenoma, and syringoma. We treated the patient with total excision, and followed up during 1 year. The patient showed no recurrence.

Significance of Peanut Agglutinin in the Differentiation between Nevocellular Nevus and Malignant Melanoma / 대한피부과학회지

Using peanut agglutinin(PNA), neurarninidase, and avidin-biotin peroxidase com plex(ABC) technique, normal skin specimens, nevocellular nevi, and malignant melanomas were studied, and different PNA binding patterns between nevocellular nevi and malignant melanomas were observed. The results were as follows : 1. In normal skin, except the basement membrane, epidermis and hair follicle epithelium showed a cell membrane staining of PNA after neuraminidase pretreat ment. Sebaceous glands revealed membranous and cytoplasmic staining of PNA, but sweat ducts were not stained. 2. In nevocellular nevi, none of the nevus cells were stained with PNA aftet neuraminidase preteatment. 3. In malignant melanomas, all of the melanorna cells were stained along the cell mernbrane with PNA after neuraminidase pretreatment. Therefore, the PNA staining after neuraminidase pretreatment on paraffin embedded sections using ABC technique is considered to be a useful probe for the differentiation between malignant malanoma and nevocellular nevus.