ABSTRACT
Osteosarcomas are primary malignant tumors of bone that are characterized by the production of osteoid or immature bone by the malignant cells. Osteosarcomas are uncommon tumors. Most articles reveal difficulty in diagnosing osteosarcoma in early stage due to its resemblance to benign lesion. That’s why we prefer to do case report for documentation. Diagnosis of the tumor is important especially in early stages for improving prognosis. This case report is of a 21 years old female who presented at Primary Health Care Centre with swelling above right knee post trauma a month ago. Previously she was diagnosed as Non ossifying fibroma (which is a benign lesion and uncommon to change to malignant lesion) at the same site in 2017.
ABSTRACT
Objective To improve the accuracy of diagnosis and differential diagnosis of nonossifying fibroma (NOF) by comparing with the image features of X-ray and CT and pathological characteristics,Methods The images of X-ray and CT of 28 patients underwent surgery and pathological confirmed NOF were studied retrospectively.Results NOF often occurred in the metaphysis of long bone or backbone with mild clinical symptoms.Eighteen lesions occurred in tibia,9 in femur and 1 in humerus.In 19 cortical cases,there was a single room or multiple rooms translucent zone in cortex or subcortex with dense surrounding.In 9 medullary cases,lesions as a single room or multiple rooms ranslucent zone with dense surrounding developed in the central area of the bone with thinning corex slightly bulg ed to periphery.Conclusion The images of NOF have some characteristic.X-ray and CT are very useful tools in diagnosis of NOF.Thin layer scanning and multiplanar reconstruction of multi-layers spiral CT can more clearly show the imaging features of NOF.
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Objective To investigate the imaging appearances of non-ossifying fibromas in healing stage and its clinical value.Methods The imaging features of non-ossifying fibroma in healing stage in 10 cases followed-up clinically(2 cases of them were verified by pathology after operation) were analyzed. All of the cases were examined by radiography,4 cases were examined by CT, 1 case underwent MRI. Results All of the cases were located in long bone of lower extremity. 8 cases were in tibia,2 cases were in femur. 5 cases were shown as homogeneous sclerosis,lucent areas were presented in sclerotic foci in 5 cases. 5 cases were unchangeable after followed-up 1 to 4 years .Conclusion The non-ossifying fibroma is being sclerotic stabilized foci after puberty , no operation is necessary for the healed form non-ossifying fibroma.
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Objective To evaluate the value of diagnosis of NOF by plain film and CT.Methods Radiographic and CT findings in 14 patients (male 11,female 3;age range,9～51 years)with non-ossifying fibroma proved pathologically and surgically were analysed.Results The age of 9 patients (64.3%)was between 10 and 20 years.Most of non-ossifying fibromas occured in lower extremity,especially around the knee.The X-ray findings could be divided into two types:(1)Cortical type(6 cases);(2)Medullary type(8 cases).The CT signs included:(1)Local destruction of the adjacent cortex;(2)Bone septum;(3)Well-defined sclerotic edge near the medulla.Conclusion Most of the NOF of bone can be diagnosed correctly by radiography and CT.
ABSTRACT
The term “non-ossifying fibroma of bone” was introduced by Jaffe and Lichenstein in 1942 to describe a distinctive benign lesion occuring near the ends of the long bones in young people, and the lesion was subsequently described by Hatcher as a developmental defect rather than a true tumor. This lesion was presented as a clear-cut entity on the basis of pathological, clinical and roentgenographic manifestations. The diagnosis of non-ossifying fibroma was made by the histopathological findings of the curetted tissues. The authors have seen and studied 5 cases of non-ossifying fibroma from February 1976 to September 1981. The average duration of follow up was 2.2 years, with a range from 0.8 to 5 years, and the results of treatment were as follows: l. Of the five cases, two were associated with pathologic fractures. 2. The sites of the lesions in all cases were the long bones in the lower extremity. 3 In all cases, the complaints were of only a few days or weeks duration before admission to the hospital, and no cases were discovered incidentally by roentgenographic examination. 4. Good results were obtained by treatment with curettage and bone graft.