The Differences in Resting Pulmonary Function in Relation to the Nutritional status of Patients with Chronic Obstructive Pulmonary Disease / 결핵

BACKGROUND: With cases of chronic obstructive pulmonary disease(COPD), weight loss and low body weight have been found to correlate with increased mortality and poor prognosis. Therefore, nutritional aspects are an important part of the treatment in cases of COPD. In Korea, there is only limited data available for the changes of resting pulmonary function in relation to nutritional status. This study was carried out to investigated the differences of resting pulmonary function in relation to the nutritional status of patients with COPD. METHOD: 83 stable patients, with moderate to severe COPD, were clinically assessed for their nutritional status and resting pulmonary function. The patients' nutritional status was evaluated by body weight and fat-free mass (FFM), which was assessed by bioelectrical impedance analysis. According to their nutritional status, the 83 patients were divided into two groups, designated as the depleted, and non-depleted, groups. RESULT: Of the 83 patients, 31% were characterized by body weight loss and depletion of FFM, whereas 28% had either weight loss or depleted FFM. In the depleted group, significantly lower peak expiratory flow rate(p<0.05) and Kco(p<0.01), but significantly higher airway resistance(Raw, p<0.05) were noted. There was no difference for the non-depleted group in forced expiratory volume at one second, residual volume, inspiratory vital capacity, or total lung capacity. Maximal inspiratory pressure(PImax) was also significantly lower in the depleted group(p<0.05). CONCLUSION: We conclude, from our clinical studies, that nutritional depletion is significantly associated with the change in resting pulmonary function for patients with moderate to severe COPD.

The Effect of Preoperative Nutritional Depletion on Postoperative Complications in the patient with Multiple Injuries / 대한정형외과학회잡지

The importance of maintaining appropriate nutrition in the patient with serious multiple injuries may be overlooked by the orthopedic surgeon. Nutritional depletion has a significant effect on survival, wound healing, immunocompetence, fracture healing and rehabilitation of the patient. A prospective study was performed to determine the effect of preoperative nutritional status on the postoperative complications in forty patients who had been admitted to the hospital because of multiple injuries. The parameters that were used to determine the nutritional status included serum levels of albumin, transferrin, and hemoglobin; TCL(total lymphocyte count);and CHI(creatinine height index). The results were as follows: 1. Significant preoperative nutritional depletion of moderate or severe degree in at least one of the 5 indices was indentified in 25(62.5%) of the 40 patients. 2. Incidence of preoperative nutritional depletion ranged from 7.5% for hemoglobin to 52.5% for transferrin and the nutritional depletion averged 29.5% abnormality per nutritional index. 3. Twenty complications were observed in 18 patients. 4. The incidence of preoperative nutritional depletion was 83.3% in complication group and 45.5% in non-complication group. 5. Serum albumin level and serum transferrin level had significant predictive value of postoperative complication.