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AIM: To assess the repeatability and agreement of higher-order aberration obtained by adaptive optics visual simulator(VAO)compared with OPD-Scan Ⅲ.METHODS: A cross-sectional study was conducted from August to September 2023, including a total of 204 patients(204 eyes)with myopia whose right eyes were measured. The examinations were performed by the same skilled examiner using both devices separately. The VAO device was used to measure higher order aberrations of orders 3 to 6 at a pupil diameter of 4.5 mm, while both the VAO and OPD-Scan Ⅲ devices were utilized to measure total higher-order aberration(tHOA), spherical aberration(SA), coma aberration(Coma), and trefoil aberration(Trefoil)of the entire eye at pupil diameters ranging from 3 to 6 mm. Furthermore, the repeatability of whole eye aberration measurements obtained with the VAO device was evaluated and the agreement of the two devices was assessed.RESULTS: The whole-eye higher-order aberrations measured by VAO demonstrated excellent repeatability(0.767≤ICC≤0.941, Sw<0.01 μm, TRT<0.1 μm). There was no statistically significant difference in Coma measured by VAO or OPD-Scan Ⅲ for pupil diameters ranging from 4 to 6 mm(P>0.05), while a statistically significant difference was observed in whole-eye tHOA of other pupil diameters(all P<0.05). The agreement of aberration measurements for each order between VAO and OPD-Scan Ⅲ for 3 mm pupil diameters, SA at 4 and 5 mm pupil diameter and Coma at 4 mm pupil diameter showed a 95% limit of agreement(LoA)<0.1, indicating good agreement; however, poor agreement was found for the remaining aberration measurements at different pupil diameters, with a 95%LoA>0.1, and there were significant differences in higher-order aberrations measured by two devices under a pupil diameter of 3 mm(r=0.218-0.317, P<0.01), 4 mm(r=0.406-0.672, P<0.01), 5 mm(r=0.538-0.839, P<0.01 and r=0.030-0.109, P>0.01)and 6 mm(r=0.369-0.766, P<0.01).CONCLUSION: The VAO demonstrates favorable repeatability when assessing whole-eye higher order aberration under pupil diameters of 3-6 mm. However, there is inadequate agreement and interchangeability in whole-eye higher order aberration at 3-6 mm pupil diameter between VAO and OPD-Scan Ⅲ for clinical purposes.
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AIM:To evaluate the agreement of corneal high-order aberrations from Topcon KR-1W, i.Profiler and OPD-Scan Ⅲ wavefront aberrometers in myopic adults.METHODS:A prospective clinical study. A total of 92 adult patients(92 eyes)with myopia in the department of optometry, the People's Hospital of Guangxi Zhuang Autonomous Region from June to August 2022 were enrolled. The third-order and fourth-order corneal aberrations at the pupil diameter of 4 and 6mm were measured by Topcon KR-1W, i.Profiler, and OPD-Scan Ⅲ, respectively. The difference and agreement of the three aberrometers were evaluated.RESULTS: The measurements at 6mm pupil diameter were all greater than those at 4mm pupil diameter. Although there were no statistical differences in the measurements of Z-44、Z-24 by the three aberrometers at 4 pupil diameter(P>0.05), there were statistical differences in other measurements(P<0.05). The aberration results measured by the three aberrometers were statistically different at the 6mm pupil diameter(P<0.05). The 95% limit of agreement(95%LoA)of the measurements of higher-order aberration, including the third-order aberrations at 4mm pupil diameter and the third-order and fourth-order aberrations at 6mm pupil diameter(except for the Z-24)were greater than 0.1μm. The concordance correlation coefficient(Pc)was lower than 0.90, indicating a poor consistency. The correlation coefficients of corneal higher-order aberrations were significantly different among the three aberrometers at 4 and 6mm pupil diameter(r4mm=0.215～0.805, P4mm<0.05; r6mm=0.561～0.916, P6mm<0.001).CONCLUSION:There were significant differences in the measurements of the third- and fourth-order corneal aberrations at 4 and 6mm pupil diameter among Topcon KR-1W, i.Profiler, and OPD-Scan Ⅲ, and the agreements were poor, so they are not interchangeably in clinical applications.
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@#AIM: To evaluate the visual quality of patients with high myopia complicated with cataract after implantation of trifocal intraocular lens by OPD-Scan Ⅲ aberration analyzer.METHODS: Totally 32 patients(38 eyes)with high myopia complicated with cataract who underwent femtosecond laser assisted cataract phacoemulsification combined with trifocal intraocular lens implantation in Foshan Aier Eye Hospital from June 2018 to December 2020 were selected. Uncorrected distance visual acuity(UCDVA), uncorrected intermediate visual acuity(UCIVA)and uncorrected near visual acuity(UCNVA)were compared before, and 1wk, 3mo after surgery; OPD-Scan Ⅲ aberration analyzer measured objective visual quality before, and 1wk and 3mo after surgery. RESULTS: There were significant differences in UCDVA, UCIVA and UCNVA before, and 1wk, 3mo after operation(<i>P</i><0.05). The average orientation and centration distance was 0.12(0.08-0.15)mm and the average axial was(212.68±90.45)°in 3mo postoperative. There were significant differences in spherical aberration(<i>P</i><0.05), Strehl ratio(SR)and area ratio(AR)before, and 1wk, 3mo after operation(<i>P</i><0.001). In comparison, SR at 1wk and 3mo postoperative was higher than that before operation, whereas AR in 1wk and 3mo postoperative were both higher than that before operation(all <i>P</i><0.001). There was a negative correlation between SR and spherical aberration at 3mo postoperative(<i>rs</i>=-0.420, <i>P</i><0.01); There was a negative correlation between SR and trefoil at 3mo postoperative(<i>rs</i>= -0.418, <i>P</i><0.01); There was a negative correlation between AR and trefoil at 3mo postoperative(<i>rs</i>=-0.400, <i>P</i><0.05).CONCLUSION: Femtosecond laser assisted cataract surgery combined with trifocal intraocular lens implantation can provide a comfortable and natural full-range vision. The orientation and centricity of trifocal intraocular lens using OPD-Scan Ⅲ has shown that there was a good reliability and consistency. The vision quality using OPD-Scan Ⅲ is satisfactory.
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@#AIM: To analyze the consistency and accuracy of the axial position of the astigmatism correction intraocular lens(Toric IOL)measured by OPD scan Ⅲ(optical path difference analyzer)and the traditional slit lamp method.<p>METHODS: A prospective observational control study. A total of 118 patients with 156 eyes who underwent phacoemulsification combined with Toric IOL implantation in our hospital from July 2018 to October 2019 were selected. The residual astigmatism was followed up at 1wk, 1mo and 3mo after the operation, and the axial position of Toric IOL was measured with OPD scan Ⅲ under the small pupil(Axial intraocular astigmatism method)and after dilated pupils(Axial OPD method), while using traditional slit lamp method to measure Toric IOL axis position(Axial Slit method). Analyze the difference and consistency of the measurement results of the three methods, and calculate the Lens axis deviation(LAD)between the measurement results of the three methods and the target axis. <p>RESULTS: The residual astigmatism of the patients in this group was significantly lower than that before the operation at 1wk, 1mo and 3mo after operation(<i>P</i><0.05). The proportion of residual astigmatism ≤ 0.75D at 3mo after surgery was 73.7%. Three months after the operation, the axial position of the Toric IOL measured by the axial Slit method, the axial OPD method, and the axial intraocular astigmatism method were: 111.0°(10, 178)°, 113.5°(12, 180)°, and 113.0°(15, 178)°. Consistency analysis showed that the average value of the difference between the axial OPD method and the axial Slit method, the axial intraocular astigmatism method and the axial slit method, the axial OPD method and the axial intraocular astigmatism method at 3mo after the operation, they were -0.58°, -0.19°, 0.40°, which were all close to 0°, with high consistency. 95% <i>LoA</i> were(-7.01-5.84)°,(-12.44-12.07)°,(-10.69-11.49)°. At 3mo postoperatively, the proportions of patients with LAD ≤5° measured by axial Slit method, axial OPD method, and axial intraocular astigmatism were 82.0%, 80.1%, and 59.0%, respectively.<p>CONCLUSION: OPD scan Ⅲ can directly measure Toric IOL axial position after dilated pupils. It was an objective and accurate measurement method, which can replace the traditional slit lamp method to measure axial position and avoid subjective limitations. The Toric IOL axial position can also be measured by intraocular astigmatism under the small pupil, which has certain practical application value in ophthalmology clinical work.
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@#AIM: To explore the Accuracy of OPD-Scan III labeling method in corneal astigmatism before Toric intraocular lens implantation(IOL).<p>METHODS: Totally 100 patients with cataract were randomly divided into the control group and the observation group according to the random number table, 50 cases each. The control group used a slit lamp horizontal narrow band labeling method. The observation group used the OPD-Scan III labeling method. The preoperative and postoperative corneal astigmatism and naked eye visual acuity were compared between the two groups. The axial dislocations of the two groups were measured at 1mo and 3mo after operation.<p>RESULTS: At 3mo after operation, corneal astigmatism(0.56±0.29、0.58±0.27D)decreased significantly in the two groups. The visual acuity of the naked eye was significantly higher than that before surgery. The corneal astigmatism(<i>t</i>=0.356, <i>P</i>=0.721)and the visual acuity of the naked eye were compared between the two groups(<i>t</i>=0.587,<i> P</i>=0.558). The IOL axial deviations were compared between the two groups at 1d and 3mo after surgery(<i>P</i>>0.05).<p>CONCLUSION: Before Toric IOL implantation, OPD-Scan III and slit lamp horizontal narrow band labeling method are equally accurate in labeling corneal astigmatism and without traumatic.
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·AIM: To evaluate higher order aberrations (HOAs) of the corneal surface in normal and keratoconic eyes. ·METHODS:Using an OPD-Scan Ⅱ wavefront analyzer, aberrometric parameters of the corneal surface in one eye of 80 patients with keratoconus (KC) and 91 participants with normal eyes were evaluated. The Zernike coefficients from third- to sixth-order as well as root mean square (RMS) of primary coma, coma-like aberrations, and total HOA were calculated and compared between both groups. · RESULTS: Statistically significant differences were found in all aberrometric parameters between the measurements of the KC and normal participants (P<0.001). All of the aberrometric parameters were significantly higher in the KC patients compared to the normal group (P<0.001). ·CONCLUSION: Corneal wavefront measurements by means of OPD - Scan Ⅱ were significantly higher in keratoconic corneas than normal corneas.
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AIM:To investigate the clinical significance of aberrations difference using OPD-Scan aberrations tester after phacoemulsification.METHODS:Totally 1000 cataract patients (1 425 eyes) with nuclear grade Ⅱ with phacoemulsification and IOL implantation in our hospital from January 2013 to December 2016 were selected,with 996 cases (1421 eyes) met the inclusion criteria and received corneal wavefront aberrations examination by the same technicians at preoperative 1d and postoperative 3mo to get the 6 order 27 items Zernik coefficients,RMS1 ～ 6,RMSg and RMSh,contrast on Zernik coefficient,RMS1 ～ 6 and RMSg and RMSh.Intraocular lens type and RMS's Logistic regression analysis were conducted,the IOL on postoperative RMS was analyzed.RESULTS:The statistics showed that among 1-27 items of Zernik coefficient,only Z4,Z9,Z12 and Z24 before and after surgery showed significant difference (P＜0.05),and each postoperative Zernik coefficient dropped sharply than that before surgery,there was difference before and after surgery (P＜0.05).After operation,RMS1,RMS2,RMS3,RMS4,RMS5,RMS6,RMSg and RMSh decreased markedly than those before operation (P＜ 0.05).There was no significant difference on RMS between different types of IOL before operation (P＞ 0.05).RMS3,RMS4,RMS5,RMSg and RMSh of the aspheric surface were significantly lower than those of the spherical IOL group (P＜0.05).There was no significant difference on visual acuity (LogMAR) between the two groups before operations (P＞0.05).At 3mo after the operation,visual acuity were significantly better than those before surgery,and the LogMAR visual acuity was better in the aspheric IOL group (P＜0.01).By Pearson analysis,the overall higher order aberrations and Z420 were negatively correlated with the best corrected visual acuity after surgery (r=-0.354,-0.269;P＜0.05),while Z400 had a positive correlation with postoperative best corrected visual acuity (r=0.279,P＜0.05).CONCLUSION:RMS1 ～ 6,RMSg and RMSh aberrations reduce markedly than those before operation after phacoemulsification and IOL implantation.There is a certain relevance between the higher order aberrations and postoperative visual acuity.High-order aberrations are related to the choice of intraocular lens type,aberration measurement shall be taken to assure a reasonable and scientific selection of intraocular lens type.
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AIM:To compare the refractive errors measured by the VISX WaveScan, OPD - Scan Ⅲ and the subjective refraction. METHODS: Seventy - six patients ( 152 eyes ) were recruited from January 2013 to December 2013. All patients were measured with subjective refraction by the phoropter (NIDEK, RT-5100), objective refraction by the WaveScan ( AMO Company, USA) , OPD-ScanⅢ ( Nidek Technologies, Japan). The sphere, cylinder, axis of the three methods were compared and analyzed. RESULTS: The sphere measured by WaveScan was lower than that by subjective refraction, the difference was 0. 13±0. 30D (t=3. 753, P0. 05). The value of the difference between WaveScan and subjective refraction was 5. 87o±6. 19o for the axis and the difference between OPD-Scan Ⅲ and subjective refraction was 3. 82o±3. 95o. There was statistic significance (t=2. 817, P=0. 006). CONCLUSION: For sphere and cylinder, WaveScan generated some deviation relative to subjective refraction. The Nidek OPD-ScanⅢ gives more accurate measures of objective refraction when compared with subjective refraction.
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PURPOSE: To compare and evaluate the total and internal aberrations measured by two aberrometers: the laser ray tracing aberrometer (iTrace, Tracey Technology) and the automatic retinoscope aberrometer (OPD Scan, Nidek). METHODS: A total of 54 healthy eyes were enrolled in the study. Following pupil dilation, aberrations were measured with the iTrace and OPD Scan. We compared the aberrations obtained from measurements obtained at pupillary diameters of 4 mm and 6 mm with the OPD Scan and iTrace. Aberrations of internal optics and total aberrations were compared for the two aberrometers. For each aberrometer and each eye, the averaged Zernike data were used to calculate various root-mean-square (RMS) data. These parameters, together with the refractive parameters, were then analyzed and complimented by paired t-tests. RESULTS: At a pupil diameter of 4 mm, the number of total aberrations in the entire eye showed significant differences for the mean values of spherical aberrations (Z4,0) obtained with the OPD Scan and iTrace aberrometers (p=0.001). Aberrations of the internal optics showed significant differences in the mean values of total RMS, coma (Z3,-1), and trefoil (Z3,3) between the iTrace and OPD Scan (p<0.001, p=0.01, p<0.001) for the same pupil diameter of 4 mm. At a pupil diameter of 6 mm, the two instruments showed a similar number of total aberrations. Aberrations of the internal optics showed significant differences in the mean values of total RMS, spherical aberration (Z4,0), and coma (Z3,-1) between the two devices (p<0.001, p=0.01, p<0.001). CONCLUSIONS: The iTrace and OPD Scan showed the largest number of differences for aberrations of internal optics rather than total aberrations for both pupil diameters. These results suggest that in healthy eyes, the two aberrometers may vary in some details. The aberrometers showed more agreement at a pupil diameter of 6 mm compared to 4 mm.