ABSTRACT
Objective To explore the incidence of olfactory dysfunction in patients with Parkinson disease and the characteristic as well as its possible influencing factors. Methods The SS-12 was used to evaluate the olfactory function of 106 patients with Parkinson's disease and 110 healthy volunteers. The data was then compared between the two groups to investigate the correlation of olfactory function with age, gender, education, smoking, disease duration, Hohn-Yahr stage, UPDRSⅢscores, the dosage of levodopao and olfactory scores. Results Mean identification scores were significantly lower in patients(5.97 ± 2.27)than in controls(8.04 ± 2.00)(t=7.108, P=7.108). Parkinson's disease group did worse than the control group in identifying some odors including peppermint, bananas,liquorice,coffee,pineap?ple,rose and fish (P0.05). Conclusion Olfactory dysfunction occurs in Parkinson disease with an hign incidence rate. Olfactory function has nothing to do with disease duration, Hohn-Yahr stage, UPDRSⅢscores and the dosage of levodopa in Parkinson disease.
ABSTRACT
OBJECTIVES: Odors used in an odor identification test should be familiar to the subject, but there are some unfamiliar distracters in Korean version of Sniffin' stick (KVSS) II identification test. In this study, we used the results of the original version of KVSS II identification to modify the KVSS II identification test. METHODS: Eighty-three participants took an original version of KVSS II identification test and a visual analogue scale of subjective odor function. KVSS II identification which has 16 items was performed to choose one out of four odors items. And visual analogue scale was checked from 0 to 10 points of their subjective olfactory function. Two weeks later they took the modified version of KVSS II identification test. Hyposmic or anosmic patients were excluded. RESULTS: The mean score of the original version of KVSS II identification and modified version of KVSS II identification were 11.3 and 12.5, respectively (P<0.05). The KVSS II identification test and subjective olfactory function were positively correlated (r=0.247, P<0.05), as were the modified KVSS II identification test and subjective olfactory function (r=0.329, P<0.05). CONCLUSION: After modification of distracters, KVSS II identification test appears to be suited for assessment of olfactory function.
Subject(s)
Humans , OdorantsABSTRACT
BACKGROUND AND OBJECTIVES: KVSS (Korean Version of Sniffin' Sticks) identification test using 16 odorants familiar to Koreans is used for evaluation of olfactory function. We analyzed the correct-answer rate of the odor identification test among KVSS test to validate the reliability of these odorants. SUBJECTS AND METHOD: From April 2004 through August 2006, 720 patients underwent an odor identification test and from these, 441 patients who scored more than 9 were included. The score groups were divided into 4 groups: more than 9, 10, 11 and 12 score group. The age groups were divided into 4 groups: 0-19, 20-39, 40-59, 60 and more than 60 year-olds. The differences in the correct-answer rates of the odorant were investigated according to the score groups, age groups and sex were calculated using SPSS software. RESULTS: The odorant 6 (lemon), 7 (licorice), 8 (pine resin), and 11 (apple) showed low correct-answer rates than other odorants. Especially the correct-answer rates of odorant 7 and 11 were significantly lower than other odorants except odorant 6 and 8 in all score groups, in all age groups and both sex (p< or =.001). CONCLUSION: In the odor identification test, odorants 7 and 11 had low reliabililty for evaluation of the olfactory function, maybe due to unfamiliar odorants to Koreans or test pen failure and they had better be changed into more reliable odorants. For that, we need further investigations about KVSS test before widely used.