Advances in expansion property of stent in vessels with different shapes / 医用生物力学

The implantation of an intravascular stent has become a widely used minimally invasive treatment for coronary heart diseases due to its minimal invasiveness and high efficiency.But the long-term outcomes are often compromised by in-stent restenosis (ISR),which severely restricts its practical effectiveness.In this paper,the formation mechanism of ISR was discussed,and the effects of mechanical environment on ISR were analyzed from the view of solid mechanics.The research progress of stent expansion in vessels with 4 different shapes,including straight vessel,tapered vessel,bifurcation vessel and curved vessel was reviewed.Moreover,the correlations between vessel stress and vessel shape change caused by stent expansion and ISR were reviewed.Finally,based on the influence of different vessel shapes on stent expansion,a multi-objective optimization design method was proposed to improve the stent expansion performance and reduce the occurrence of ISR.

Advances in expansion property of stent in vessels with different shapes / 医用生物力学

The implantation of an intravascular stent has become a widely used minimally invasive treatment for coronary heart disease due to its low invasiveness and high efficiency. But the long-term outcomes are often compromised by in-stent restenosis (ISR), which severely restricts its effectiveness in practical. In this paper, the formation mechanism of ISR was given, and the effects of mechanical environment on ISR were analyzed from the view of solid mechanics. The research progress of stent expansion in vessels with 4 different shapes, including straight vessel, tapered vessel, bifurcation vessel and curved vessel was reviewed. Moreover, the correlations between vessel stress and vessel shape change caused by stent expansion and ISR were reviewed. Finally, based on the influence of different vessel shapes on stent expansion, a multi-objective optimization design method was proposed to improve stent expansion performance and reduce the occurrence of ISR.

Advances in expansion property of stent in vessels with different shapes / 医用生物力学

The implantation of an intravascular stent has become a widely used minimally invasive treatment for coronary heart diseases due to its minimal invasiveness and high efficiency.But the long-term outcomes are often compromised by in-stent restenosis (ISR),which severely restricts its practical effectiveness.In this paper,the formation mechanism of ISR was discussed,and the effects of mechanical environment on ISR were analyzed from the view of solid mechanics.The research progress of stent expansion in vessels with 4 different shapes,including straight vessel,tapered vessel,bifurcation vessel and curved vessel was reviewed.Moreover,the correlations between vessel stress and vessel shape change caused by stent expansion and ISR were reviewed.Finally,based on the influence of different vessel shapes on stent expansion,a multi-objective optimization design method was proposed to improve the stent expansion performance and reduce the occurrence of ISR.

Advances in expansion property of stent in vessels with different shapes / 医用生物力学

The implantation of an intravascular stent has become a widely used minimally invasive treatment for coronary heart diseases due to its minimal invasiveness and high efficiency.But the long-term outcomes are often compromised by in-stent restenosis (ISR),which severely restricts its practical effectiveness.In this paper,the formation mechanism of ISR was discussed,and the effects of mechanical environment on ISR were analyzed from the view of solid mechanics.The research progress of stent expansion in vessels with 4 different shapes,including straight vessel,tapered vessel,bifurcation vessel and curved vessel was reviewed.Moreover,the correlations between vessel stress and vessel shape change caused by stent expansion and ISR were reviewed.Finally,based on the influence of different vessel shapes on stent expansion,a multi-objective optimization design method was proposed to improve the stent expansion performance and reduce the occurrence of ISR.

The Application Effect of Optimization Design of County-level Hospitals Electronic Admission Nursing Evaluation Table / 昆明医科大学学报

Objective To study the application effect of optimization design of electronic admission nursing evaluation table.Methods We investigated the nursing staff satisfaction,hospitalized patients satisfaction and nursing quality sensitive indicators (expected pressure sores,pipe slips,falls / falling bed) before and after optimization design,and compared the difference between them.Results The nursing staff satisfaction was significantly higher than that before optimization design (P＜0.05),patient satisfaction was significantly higher than that before optimization design (P＜0.01),nursing quality sensitive indicators was significantly lower than that before optimization design (P ＜0.05).Conclusion The optimized design of electronic admission nursing evaluation table is detailed,objective,simple to use,and more objective and scientific in quality sensitive indicators control,and has good clinical practibility.

Application of RBF and RSM in Optimizing the Processing Conditions of Manchurian Dutchmanspipe Stem with Alkali / 医药导报

Objective To optimize the processing conditions of Manchuiran Dutchmanspipe Stem with alkali. Methods The combination of radial basis function ( RBF) and response surface methodology ( RSM) was used to investigate the influence of NaHCO3 , concentration, duration and cycles of processing on the content of aristolochic acid. Results The optimal process was achieved when Manchuiran Dutchmanspipe Stem was soaked for 3 cycles in 0. 05 mol·L-1 NaHCO3 solution, for 24 hours in each cycle. The removal rate of total aristolochic acid approached to 83. 74%. Conclusion The combination of RBF and RSM provided a new method and good guidance for further toxicity attenuation for Manchuiran Dutchmanspipe Stem.

Optimization design and structural requirement for clinical fluorogenic quantitative polymerase chain reaction laboratory / 医疗卫生装备

Fluorogenic quantitative polymerase chain reaction(FQ-PCR) is an emerging technique with high specificity,susceptibility,automatism and has been widely used for the detection and quantification of microorganism,some genetic diseases and cancer.The design and establishment of standard FQ-PCR laboratory are required not only by gene expansion and diagnosis but also by biosafty and veracity.The aim of the paper is to introduce the structural characteristics,instruments requirement and comfort parameters of FQ-PCR laboratory.