ABSTRACT
Numerous applications for three-dimensional (3D) printing are extended rapidly and expected to revolutionize manufacturing industry, as well as the various aspects of medical field. This paper summarizes the domestic and overseas literatures on 3D printing used in medical field, and shows several advantages of 3D printing technique in the application of medicine. The 3D bio-printing technique, however, still need time to be evolved. In addition, the orderly and efficient development of 3D printing within the medical field will ultimately depend on the formulation of relevant policies and regulations and ongoing evolution of technique itself, and it still need carry out more in-depth research and exploration for functional human tissue and organ with 3D printing.
ABSTRACT
Three-dimensional (3D) tissue/organ printing is a major aspect of recent innovation in the field of tissue engineering and regenerative medicine. 3D tissue/organ printing aims to create 3D living tissue/organ analogues, and have evolved along with advances in 3D printing techniques. A diverse range of computer-aided 3D printing techniques have been applied to dispose living cells together with biomaterials and supporting biochemical factors within pre-designed 3D tissue/organ analogues. Recent developments in printable biomaterials, such as decellularized extracellular matrix bio-inks have enabled improvements in the functionality of the resulting 3D tissue/organ analogues. Here, we provide an overview of the 3D printing techniques and biomaterials that have been used, including the development of 3D tissue/organ analogues. In addition, in vitro models are described, and future perspectives in 3D tissue/organ printing are identified.