ABSTRACT
Background: Organosphophorous compounds are the commonly available insecticides in households. Therefore, children are vulnerable to accidental poisoning. It is associated with significant morbidity and mortality. The aim of this study was to study the clinical profile of organophosphorous poisoning in children.Methods: This was prospective study conducted over a period of two years from January 2018 to January 2020 in department of Pediatrics, Government Medical College Srinagar, Jammu and Kashmir, India. All the patients in the age group of 1-18 years with history and examination suggestive of organophosphorous poisoning were included in this study.Results: In this study there were total of 54 patients. In majority of cases poisoning was accidental. Oral consumption was most common route of poisoning. The most common symptoms were excessive salivation (100%), vomiting (72%), abdominal pain (26%), diarrohea (13%), agitation (11%) and convulsions (3.7%). The most common signs were miosis (78%), bradycardia (59%), fasciculation (57%) and altered sensorium (13%). Respiratory failure and circulatory collapse were two main complications which contributed to mortality in this study.Conclusions: Organophosphorous poisoning is one of the most common poisoning in children. Early diagnosis and treatment is of pivotal importance to prevent mortality.
ABSTRACT
Literatures on arrhythmia induced by acute organophosphorous pesticide poisoning published in domestic journals from 1979 to 2010 were searched. Total 3468 cases of acute organophosphorous poisoning were collected and analyzed. The average abnormal ECC rate was (53 ±15)%(35. 4% -68. 4% ) in acute organophosphorous poisoning, the most common ECG abnormalities were ST-T segment changes (26. 5% ) and sinus tachycardia (16. 6% ). The rate and severity of ECG abnormalities were increased with the severity of organophosphorous poisoning(x2 = 33. 253,P < 0. 01). The most common causes of death in acute organophosphorous poisoning were ventricular tachycardia and ventricular fibrillation (26.2%).
ABSTRACT
Organophosphorous compounds are one of the efficient methods available for pest control. Because of its easy availability, the various preparations of organophosphorpus compounds cause significant morbidity and mortality to the human lives. In addition to producing pesticide related illness and death, Organophosphorous compounds produces different neurological manifestations as a sequelae to its toxicity. Four such neurological syndromes are discussed with their salient clinical features.