Study of Anatomical Variations of Number of Pulmonary Veins and its Clinical Significance

Introduction: The pulmonary veins play an important rolein the pulmonary circulation by receiving oxygenated bloodfrom the Lungs and delivering it to the left atrium. Pulmonaryvein anatomy piqued curiosity of researchers off late afterthe discovery of its role in genesis of atrial arrhythmias andincreased incidence of pulmonary hypertension in COPD.The congenital variations in number of pulmonary veinsand their drainage patterns, encompass a wide spectrum ofanomalies and are not uncommon in general population. Theaim of the study was to observe the variations in the numberof pulmonary veins and pulmonary ostia.Material and Methods: The present study was done on 25formalin fixed hearts aged 18-70 years, obtained from thedepartment of anatomy, Sri Padmavathi Medical college forwomen, Tirupathi. These hearts were observed for the numberof pulmonary veins, their drainage into left atrium, variationsin pulmonary ostia on right and left sides and were comparedwith previous studies.Results: Out of the 25 specimens studied, 23 hearts (92%)had normal pattern of four pulmonary veins, two from eachlung extending to the left atrium and opening into it via twoseparate pulmonary ostia, on either side. In 2 (8%) out of 25specimens, variations in the number of pulmonary veins andthe pulmonary ostia were observed.Conclusion: The awareness of the variant anatomy ofpulmonary veins and their drainage is of paramountimportance to Radiologists, Electrophysiologist and Cardiothoracic surgeons while performing surgical procedures onHeart.

Study Of Coronary Ostia In Preserved Human Cadaveric Heart Specimens In Western Maharashtra By Dissection Method

Introduction: Coronary artery disease is responsible for 70% cases of sudden cardiac deaths. Small coronaryostia may cause significant difficulty in canulation of it during diagnostic and therapeutic procedures. Highorigin of coronary arteries increases risk of myocardial ischaemia and sudden death. Considering thesesignificance of variations of coronary ostia in cardiac procedures, detailed study was undertaken so it would beof use to cardiologists and interventional radiologists.Material and Methods: Sample size for the study comprised of 50 human cadaveric heart specimens. Dissectionmethod was adopted.Observation and Results: In anterior aortic sinus, 41 specimens had single ostium, while 09 specimens showedtwo separate ostia. The mean of ostium diameter of right coronary artery was found to be 2.84 mm with astandard deviation (S.D.) of +0.85 mm. The mean distance of main ostium of right coronary artery fromsupravalvular ridge was found to be 1.23 mm. with a S.D. of +0.32 mm. In case of accessory ostia in anterioraortic sinus, the mean diameter was found to be 1.32 mms. with a S.D. of +0.20 mms. The mean distance of theseostia from supravalvular ridge was found to be 1.16 mms. with a S.D. of +0.17 mms. In left posterior aortic sinus,49 specimens had single ostium, while 01 specimen had two separate ostia. This ostium was 0.8 mms. indiameter at a distance of 02 mms. below from supravalvular ridge. The mean of ostium diameter of left coronaryartery was found to be 3.31 mm with a S.D.of+0.52 mm. The mean distance of main ostium of left coronary arteryfrom supravalvular ridge was found to be 1.40 mm. with a S.D. of +0.27 mm.Conclusion: the study provides data on coronary morphometry and topography. It provides basis for understandingthe normal variants for determining incidence of anomalies and for evaluating value of screening of suchanomalies.

Anatomical Study Of Coronary Ostia In Cadaveric Human Heart

The right and left coronary artery arises from the anterior and left posterior sinus of Valsalva respectively. Aortic root is an important area for various interventional diagnostic and surgical procedures for cardiologist and radiologist which comprises of the bulbar aortic sinus and the proximal ascending aorta. 50 cadaveric human heart specimens (25 male and 25 female) were used by dissection method. It has been observed that the mean diameter of left coronary ostium is more than that of right coronary ostium. The mean diameter of left coronary ostium in male is 4.37mm ± 0.84 and in female it is 4.16mm ± 0.67. On the contrary, in case of right coronary ostium the mean diameter were 3.04mm ± 0.76 and 3.14mm ± 0.70 in male and female respectively. In 18% specimens multiple openings were observed in anterior aortic sinus. However, in 4% specimen anterior aortic sinus with no openings were also observed. Multiple openings were also seen in left posterior aortic sinus in 4% specimen. No openings were observed in the pulmonary sinuses and the right posterior aortic sinus. Knowledge of the level of ostia is very important to avoid difficulties during various diagnostic and surgical procedures, hence, to extract extra information regarding these issues, study was also extended to observe the level of ostia; and in this study right coronary ostium was found below Supravalvular Ridge (SVR) in 78% specimen, at SVR in 10% specimen and above SVR in 12% specimen. The left coronary ostium was found below SVR in 68% cases, at SVR in 16% cases and above SVR in 16% cases.

Anatomical and radiological angiographic study of the coronary ostia in the adult human hearts and their clinical significance / 대한해부학회지

This study was carried out to investigate the morphometric parameters and variations of coronary ostia in the hearts of adult human cadavers and coronary angiographs. The hearts of 60 adult human cadavers and 400 coronary angiographs were used in this study. The root of the aorta was carefully dissected to clear aortic sinuses, coronary ostia, and sinutubular junction (STJ). Number, locations, internal diameter distance between coronary ostia and their corresponding STJ, sinus bottom, and valve commissures were investigated. The anterior aortic sinus (AAS) revealed a single ostium for right coronary artery (RCA) in 77.5% of male and 80% of female hearts. This ostium gave a common origin for RCA and third coronary artery (TCA) in 15% of male and 20% of female hearts. However, two separate ostia for RCA and TCA origin were seen in 20% of male and 15% of female hearts. Moreover, three ostia were seen in one male and one female hearts within AAS. Meanwhile, the left posterior aortic sinus showed a single ostium for left coronary artery (LCA) in 97.5% of male and 95% of female hearts and two ostia in one male and one female hearts. The ostia were commonly seen below STJ and less commonly were observed above STJ. The distance between the bottom of aortic sinus and LCA ostium was longer than that of RCA. The internal diameter of RCA ostium was significantly (P<0.05) narrower than that of LCA but with no significant sex difference. Moreover, anomalous of coronary ostia was observed in seven out 400 angiographs and in two cadaveric hearts. Knowledge the morphometric parameters and anatomical variations of coronary ostia helps the cardiac surgeons to overcome the possible difficulties that could occur during surgical and radiological coronary interventions.

Variations in the Number of Pulmonary Veins Draining into Left Atrium and its Clinical Significance

Pulmonary veins, normally two on each side bring oxygenated blood from lungs to left atrium. During early embryonic life, absorption of pulmonary venous network by the left primitive atrial chamber results in opening of four pulmonary veins which drain independently into its chamber. The extent of absorption and hence, the number of pulmonary veins which open into left atrium may vary

Thought experiments and the ostia of paranasal sinuses

@#It behooves us to understand the power of gravity or its diminished or negative effect as we, Homo sapiens, evolve from going around from four limbs to bipedalism or working mostly erect or sitting on our buttocks. Evolution doesn’t favor a particular desire or anticipate the future; its particular end is to get that individual to live long and propagate more efficiently. Evolution cannot give you all the favorable advantages; only that selfish genes will make us the top predators. Unfortunately the locations of the paranasal sinus ostia are not top in the list of favorable advantages. Hemorrhoids, chronic back pain, varicous veins, etc are other morbid consequences of bipedalism.

Patterns of sudanophilic lesions at ostia of descending thoracic and abdominal aorta in cholesterol-fed adult rabbits / Patrones de lesiones sudanofílicas en el ostio de las partes torácica y abdominal de la aorta en conejos adultos alimentados con colesterol

Sudan-positive atherosclerotic lesions preferentially occur at downstream and lateral margins of arterial branch ostia in human neonates and weanling rabbits but tend to develop at lateral and upstream margins in old subjects. We investigated (i) the pattern of sudanophilic lesions at aortic ostia of cholesterol-fed adult rabbits and (ii) determined any differences in lesion distribution between descending thoracic and abdominal aorta. Ten adult males, New Zealand white rabbits were fed 2 percent high cholesterol diet. After six weeks, aortas were excised, opened longitudinally and stained with Sudan-IV for gross examination of atherosclerotic lesions. A total of 156 descending thoracic and 90 abdominal ostia were examined. Mean lesion frequencies upstream, downstream and at lateral margins of the affected ostia were calculated and compared. Sudanophilic lesions were detected around 32 percent ostia of descending thoracic aorta and 25 percent those of abdominal aorta. At ostia of descending thoracic aorta, lesion frequencies were significantly higher (P<0.001) downstream (95 percent) and at lateral margins (92 percent) than upstream (2 percent). In abdominal aorta, lateral (100 percent) and upstream (43 percent) margins were significantly (P<0.05) more affected while minimal lesion frequencies were seen at downstream branch points (9 percent). Comparison between descending thoracic and abdominal aorta showed an insignificant difference of lesion frequencies at lateral margins (P>0.05) but a highly significant difference at upstream versus downstream of ostia (P<0.001). We concluded that in cholesterol-fed adult rabbits, juvenile pattern of downstream lipid deposition persists at ostia of descending thoracic aorta while a switch towards the upstream pattern of old subjects occurs at ostia of abdominal aorta.

Las lesiones ateroscleróticas Sudán-positivas se producen preferentemente en los márgenes posteriores y laterales del ostio de las ramas arteriales en neonatos humanos y en conejos destetados, pero tienden a desarrollarse en los márgenes laterales y superiores en sujetos de edad avanzada. Investigamos el patrón de lesiones sudanofílicas en el ostio aórtico de conejos adultos alimentados con colesterol y determinamos las diferencias en la distribución de lesiones entre la aorta torácica descendente y abdominal. Diez conejos machos blancos adultos New Zealand fueron alimentados con una dieta alta en colesterol al 2 por ciento. Después de seis semanas, fueron extraídas las aortas, se disecaron longitudinalmente y se tiñeron con Sudan-IV para el examen macroscópico y se observaron las lesiones ateroscleróticas. Fueron examinados 156 ostios de aortas torácicas descendentes y 90 de aortas abdominales. Fueron calculadas y comparadas las frecuencias medias de lesiones superiores, inferiores y de los márgenes laterales de los ostios afectados. Las lesiones sudanofílicas se detectaron en alrededor del 32 por ciento de ostios de la aorta torácica descendente y en el 25 por ciento de las aortas abdominales. En el ostio de la aorta torácica descendente, las frecuencias de lesiones fueron significativamente mayores (p <0,001) por superior (95 por ciento) y en los márgenes laterales (92 por ciento) que por inferior (2 por ciento). En la aorta abdominal, los márgenes laterales (100 por ciento) y superiores (43 por ciento) fueron significativamente más afectados (p <0,05), mientras que las frecuencias mínimas de lesiones se observaron en los puntos de la rama descendente (9 por ciento). La comparación entre la aorta torácica descendente y abdominal mostró una diferencia no significativa de las frecuencias de lesiones en los márgenes laterales (p> 0,05), pero muy significativa al comparar el margen superior con el inferior (p <0,001). Llegamos a la conclusión que en los conej...

The ostia venae hepaticae and the retrohepatic segments of the IVC in Thais.

144 normal adult livers were studied anatomically. The length of the retrohepatic segment of the inferior vena cava was 6.6 centimeters and was totally enclosed by liver substance in 12.5% of cases. Altogether 1,581 ostia venae hepaticae were found, on average 11 per liver and these were classified as large, medium, small or minimum. The localisation of these openings was studied according to the division of interior wall of the retrohepatic segment of IVC into 16 areas.

Scanning Electron Microscopic Study of the Eccrine Ostia of Mouse Foot Pads After Application of Antiperspirant

Recently, a topical preparation of 5% propantheline bromide and 10% aluminum hydroxychloride in an emulsion ground substance was introduced as an effective antiperspirant. According to the literature, aluminum salts may produce functional closure of swet ducts. Nevertheless, histologic study has as yet failed to reveal a solid anatomic basis for occlusion. In this study, the scanning electron microscope (SEM) was used to demonstrate eccrine gland ostial occlusion due to topical 5% propantheline bromide and 10% aluminum hydroxychloride.