ABSTRACT
Objective To analyze the serious complications of percutaneous balloon mitral valvuloplasty (PBMV). Methods Between October , 1986,and November, 2000, 1200 patients with rheumatic mitral stenosis age 9-66 older underwent PBMV by Inoue Way. 98% of the balloon catheters were self-made and single balloon catheters.Results Operative successful rate was 98.82% . Serious complications occurred in 51 patients or (4.4%), including 4 cases of death (0.33%), 5 acute serious mitral regurgitation (0.42%), 8 acute cardiac tamponade (0.66%), 28 severe arrhythmia (2.3%), 4 acute left ventricular failure and acute pulmonary edema (0.33%), and 8 systemic thromboembolis. The four cases of death included 1 with acute pulmonary edema, 1 with cardiac arrest, and 2 with acute left ventricular failure with low cardiac output. Conclusion The results demonstrate that PBMV is an efifective and reliable procedure in the treatment of rheumatic mitral stenosis, but a marked decreasement in complication rates is attributable to refinement of patient selection criterion, technical advance in procedure, and strictly management of patients.
ABSTRACT
Objective To study the effect of percutanous transluminal balloon mitral valvuloplasty(PBMV) on endothelin and endocrine hormones. Methods Plasma concentrations of endothelin(ET), atrial natriuretic factor(ANF), renin activity(PRA), angiotension Ⅱ(AⅡ) and hemodynamic changes were assessed in 14 patients with rheumatic mitral stenosis before and after PBMV. Results After the procedure, ET(80.40?19.13 pg/ml vs 161.94?50.61 pg/ml, P