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@#Introduction: Primary pancreatic lymphomas are extremely rare. Clinically, primary pancreatic lymphoma mimics symptoms of carcinoma of the pancreatic head. Clinical and radiological features may overlap with other pancreatic conditions such as carcinoma, neuroendocrine tumours and autoimmune pancreatitis. Case Report: We report a case of a 75-year-old man who presented with symptoms of obstructive jaundice. Ultrasonography and computed tomography (CT) showed an illdefined lobulated soft tissue lesion at the head/uncinate process of the pancreas measuring 4.5 x 4.9 x 5.8 cm. The patient underwent pancreaticoduodenectomy for suspected pancreatic head/uncinate process carcinoma. Histopathology and immunohistochemical assessment of the pancreatic lesion established the diagnosis of a low-grade follicular lymphoma. Discussion: Clinical and imaging features of primary pancreatic lymphoma may often overlap with pancreatic carcinoma. There is a value of obtaining preoperative tissue diagnosis such as tissue biopsy and fine needle aspiration (FNA) cytology with or without flow cytometry to make an accurate diagnosis of non-Hodgkin lymphoma and alleviate the need of more radical surgery in pancreatic lymphoma.
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Lymphoma, FollicularABSTRACT
Objective Conserved DNA-Derived Polymorphism (CDDP) markers were used in the study of the genetic diversity of 43 Dendrobium officinale and preliminary resistance screening, in order to provide a theoretical basis for the screening of D. officinale and the selection of fine varieties. Methods A total of 21 CDDP primers were used to amplify the genomic DNA of the test material with clear and polymorphic primers. Results Sixteen primers generated 151 bands, of which 144 (95.7%) were polymorphic. The results of data analysis on three population showed that the percentage of polymorphic locus (PPL) were between 65.56% and 82.12%, coefficient of genetic differentiation among natural populations (Gst) was 0.110 2, and the total gene flow (Nm) was 4.035 4. Indicating that anthropogenic factors may also promote the genetic diversity of D. officinale. Conclusion The genetic diversity of D. officinale was rich, and the results showed that there were eight plants with potentially good resistance among 43 materials.
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Objective: To assess the genetic diversity of Gentiana straminea (Gentianaceae). Methods: Intersimple sequence repeat (ISSR) markers were used. Twenty-eight populations (83 individuals) of G. straminea were sampled from Sichuan, Qinghai, Gansu provinces, and Autonomous Region of Tibet. ISSR data were analyzed with the program POPGEN, and a UPGMA dendrogram was constructed. Results: PCR products corresponding to 183 alleles at 95 loci, amplified by the seven primers were scored. Eighty-eight loci were polymorphic. Expected heterozygosity (He) and Shannon's information index (Im) were 0.288 2 and 0.437 1, respectively. Nei's coefficient of genetic differentiation (Gst) and gene flow (Nm) were 0.678 3 and 0.237 1 at the population level, respectively. The genetic distance varied from 0.074 3 to 0.490 0. G. straminea populations were mainly divided into two braches by UPGMA tree. Conclusion: Genetic diversity level of G. straminea is high, and genetic diversity level among populations of G. straminea is higher than that in one population; Its autogenous variation mainly exist among populations; Hereditary capacity has certain correlation with geographical distribution. This work contributes basic information for variety identification, species in situ conservation, and enviroment investigation on the influence of heredity differentiated and Chinese Materia Medica genuine study. The congruence between genetic distance and geographic distances is high.