ABSTRACT
Objectives: To correlate lactate clearance with Pediatric Intensive Care Unit (PICU) mortality. Methods: 45 (mean age 40.15 mo, 60% males) consecutive admissions in the PICU were enrolled between May 2012 to June 2013. Lactate clearance (Lactate level at admission – level 6 hr later x 100 / lactate level at admission) in first 6 hours of hospitalization was correlated to in-hospital mortality and PRISM score. Results: Twelve out of 45 patients died. 90% died among those with delayed/poor clearance (clearance <30%) compared to 8.5% in those with good clearance (clearance >30%) (P<0.001). Lactate clearance <30% predicted mortality with sensitivity of 75%, specificity of 97%, positive predictive value of 90%, and negative predictive value of 91.42%. Predictability was comparable to PRISM score >30. Conclusion: Lactate clearance at six hours correlates with mortality in the PICU.
ABSTRACT
We conducted this study to evaluate the outcome of 203 patients admitted to PICU, using PRISM score. Overall mortality was 16.7%. The mean PRISM score was 6.5±3.6 and 15.5±7 for survivors and non survivors, respectively (OR: 1.36; 95% CI=1.24–1.5; P<0.001). PRISM score also correlated well with length of hospital stay and the number of organ failures (P<0.001). A cut off score of 15 was associated with 89.2% accuracy. PRISM score is highly sensitive in predicting the outcome of pediatric patients in an ICU setting.