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Doppler ultrasonography is the main modality for imaging of hemodialysis AV ?stula as it is safe and non-invasive. This study is to measure the Arterio-venous (AV) ?stula blood ?ow during early postoperative period (0–7days) and assess its role in AV ?stula failure prediction. Doppler ultrasonography was used to estimate the blood ?ow in the AV ?stula of 50 patients at (0–7days) after the ?stula was made. The blood ?ow in ?stula during early postoperative period for ?stula failure was evaluated, and long term failure was predicted. Blood ?ow rates Method measured in arteriovenous ?stula created in upper extremity were measured in ?rst week and sixth week post-operative. Results After follow up evaluation out of 50 patients, 40 ?stulas considered to be matured; 10 considered failed. 30% failure were males and 70% were female. In early post operative period, cut off was set at 182 ml/min and the sensitivity of blood ?ow for prediction of ?stula failure is 98%, speci?city 90 %, PPV 95% and NPV 90%. Measurements of the AV ?stula blood Conclusion ?ow in proximal artery and draining vein with its diameter of lumen were noted in the early postoperative period has a role predicting AV ?stula failure. There is risk of failure if the blood ?ow less than 182 ml/min (day 0–7)
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Background: The purpose of the study is to evaluate the role of uterine artery blood flow parameter measured by uterine artery two-dimensional (2D) power coloured doppler (PCD) ultrasound in predicting fertility outcomes in women undergoing ART treatment.Methods: It is prospective observational study. Total of 60 patients were included of receiving infertility treatment in the age group20-40 years. 20 patients were selected for timed intercourse , 20 patients were selected for intrauterine insemination , 20 patients were selected for invitro fertilization. Transvaginalsonography will be done on the day of trigger by BHCG , UA PSV were measured, and endometrial blood flow will be assessed. Predictivity of pregnancy rate will be looked after by 3 ways: BHCG values , UPT, Gestational sac on USG.Results: In TI/IUI/IVF cycles the Doppler parameter PSV of uterine artery (23.08+/-3.39 vs 20.37-/+5.43) in pregnant vs non-pregnant group did not differ significantly. The mean PSV of UA shows no significant difference women who were became pregnant during treatment and the women who were not became pregnant.Conclusions: With help of Doppler parameter imaging of women undergoing infertility it was found that UA PSV is non-significant to decide the prediction of pregnancy outcome.
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Porcine teschovirus (PTV), porcine sapelovirus (PSV), and enterovirus G (EV-G) are infectious agents specific to pig host species that are endemically spread worldwide. This study aimed to investigate the natural infection by these porcine enteric picornaviruses in wild boars (Sus scrofa scrofa) of Paraná state, Brazil, and to evaluate peccaries (Pecari tajacu and Tayassu pecari) as alternative host species for these viruses. Fecal samples (n=36) from asymptomatic wild boars (n=22) with ages ranging from 2 to 7 months old (young, n=14) and 2 to 4 years old (adult, n=8) and from peccaries (6 to 8 months old, n=14) were collected from a farm and a zoo, respectively, both located in Paraná state. Reverse transcription-polymerase chain reaction (RT-PCR) and nested-PCR (n-PCR) assays targeting the 5'non-translated region of the virus genome were used for screening the viruses. Porcine enteric picornaviruses were detected in 12 out of the 22 wild boar fecal samples. According to each of the viruses, EV-G was most frequently (11/22, 50%) detected, followed by PTV (10/22, 45.5%) and PSV (4/22, 18.2%). Regarding the age groups, young wild boars were more frequently (9/14, 64.3%) infected with PTV, PSV, and EV-G than adult animals (3/8, 37.4%). One n-PCR amplified product for each of the viruses was submitted to sequencing analysis and the nucleotide sequences were compared with the related viruses, which showed similarities varying from 97.7% to 100% for PTV, 92.4% to 96.2% for PSV, and 87.1% to 100% for EV-G. Peccaries tested negative for the viruses and in this study they did not represent infection reservoirs. This study is the first to report the molecular detection of PTV, PSV, and EV-G from captive wild boars in a South American country and the first to screen peccaries as alternative host species for porcine enteric picornavirus.
Teschovírus suíno (PTV), sapelovírus suíno (PSV) e enterovírus G(EV-G) são agentes infecciosos específicos da espécie suína que estão endemicamente disseminados em todo o mundo. O objetivo deste estudo foi investigar a infecção natural por estes picornavírus entéricos suínos em javalis (Sus scrofa scrofa) do estado do Paraná, Brasil e avaliar pecaris (Pecari tajacu e Tayassu pecari) como hospedeiros alternativos para estes vírus. Amostras fecais (n=36) de javalis assintomáticos (n=22) com idades de 2 a 7 meses (jovens, n=14) e 2 a 4 anos (adultos, n=8) e de pecaris (6 a 8 meses de idade, n=14) foram coletadas em um cativeiro e zoológico, respectivamente, ambos localizados no estado do Paraná. A transcrição reversa seguida por reações da polimerase em cadeia (RT-PCR) e nested-PCR com alvo na região 5'-não traduzida do genoma viral foram utilizadas para a identificação dos vírus. Picornavírus entéricos suínos foram detectados em 12 das 22 amostras fecais de javalis. De acordo com cada um dos vírus, EV-G foi mais frequentemente (11/22, 50%) detectado, seguido pelo PTV (10/22; 45,5%) e PSV (4/22; 18,2%). Considerando os grupos de idade, javalis jovens foram mais frequentemente (9/14; 64,3%) infectados com PTV, PSV e EV-G do que os javalis adultos (3/8; 37,4%). Um produto amplificado na nested-PCR para cada um dos vírus foi submetido à análise de sequenciamento e as sequências de nucleotídeos foram comparadas com vírus relacionados, o que mostrou que as similaridades variaram entre 97,7% a 100% para o PTV, 92,4% a 96,2% para o PSV e 87,1% a 100% para o EV-G. Os pecaris foram negativos para as viroses investigadas e neste estudo não se apresentaram como hospedeiros alternativos para as infecções. Este estudo é o primeiro a relatar a detecção molecular de PTV, PSV e EV-G em javalis de cativeiro de um país da América Latina e o primeiro a avaliar pecaris como espécie hospedeira alternativa para picornavírus entéricos suínos.
Subject(s)
Animals , Enteroviruses, Porcine/pathogenicity , Picornaviridae Infections/veterinary , Picornaviridae Infections/virology , RNA, Viral , Sus scrofa/virology , Teschovirus/pathogenicity , Genome, Viral , Reverse Transcription , Real-Time Polymerase Chain Reaction/veterinaryABSTRACT
A presença de anastomoses vasculares placentárias nas gestações gemelares monocoriônicas favorece o surgimento de complicações graves como a Síndrome de Transfusão Feto-Fetal (STFF) e a Sequência Anemia-Policitemia em Gêmeos (TAPS). STFF e TAPS são ambas formas crônicas de transfusão feto-fetal. TAPS, descrita em 2007, é caracterizada por anemia crônica no gêmeo doador e policitemia no gêmeo receptor, na ausência de discordância no volume de líquido amniótico, característica da STFF clássica. O diagnóstico pode ser feito pré- e pós-natal. O critério diagnóstico pré-natal é baseado na discordância intergemelar da medida do Doppler do pico de velocidade sistólica da artéria cerebral média (PSV-ACM). O diagnóstico pós-natal é baseado na grande diferença da hemoglobina intergemelar, ao nascimento, e reticulocitose no gêmeo doador.(AU)
The presence of placental vascular anastomoses in monochorionic twins favors the development of several complications like Twin-Twin Transfusion Syndrome (TTTS) and Twin Anemia-Polycythemia Sequence (TAPS). TTTS and TAPS are both chronic forms of fetofetal transfusion. TAPS, described on 2007, is characterized by chronic anemia in the donor twin and polycythemia in the recipient twin, in the absence of amniotic fluid volume discordances, characteristic of classical TTTS. The diagnostic can be made pree posnatally. The prenatal diagnostic criteria is based on the inter-twin discordance in Doppler measurement of peak systolic velocity in the middle cerebral artery (MCA-PSV). The postnatal diagnosis is based on large intertwin hemoglobin difference at birth and retoculocytosis in the donor twin.(AU)
Subject(s)
Humans , Female , Pregnancy , Infant, Newborn , Polycythemia/congenital , Ablation Techniques/methods , Fetofetal Transfusion/surgery , Fetofetal Transfusion/classification , Fetofetal Transfusion/diagnostic imaging , Anemia/congenital , Prenatal Diagnosis , Blood Pressure , Hemoglobins/deficiency , Databases, Bibliographic , Ultrasonography, Doppler/methods , Middle Cerebral Artery/diagnostic imagingABSTRACT
Objective To explore the application value of ultra -high frequency ultrasound in detection of femoral artery stenosis in rabbits.Methods Twenty-four healthy male New Zealand white rabbits (body weight 2.5 -3.0 kg) were randomly divided into three groups , 8 rabbits in each group.Preparation of femoral atherosclerosis model : the rabbits were fed with high fat diet for 4 weeks, 8 weeks and 12 weeks after femoral artery balloon injury , respectively.The changes of cholesterol level were observed .We used ultra-high frequency ultrasonic probe to observe the femoral artery , to assess the diameter stenosis rate and peak systolic velocity (SPV) at the symptomatic side, and the histological areal stenosis was evaluated.Results 1.The blood cholesterol levels were increased after fed high cholesterol diet , with a significant difference among the groups (P <0.001); 2.There was a stenosis to a different degree in the modeling artery after fed high cholesterol diet for 4 wks, 8 wks, and 12 wks, and the stenosis degree was increased gradually .At 12 w, the degree of stenosis was higher than that at 4 w and 8 w, respectively, showing statistical significance ( P <0.001).At the symptomatic side, the peak systolic flow velocity was increased , and it was higher at 12 w than that at 4w and 8 w, respectively.3.With the extension of time, the arterial stenosis rate was increased along with the time course (P <0.05). Conclusions 1.High fat diet combined with balloon injury can cause varying degrees of rabbit femoral artery stenosis ; 2. Ultrahigh frequency ultrasound can clearly show different degrees of rabbit femoral artery stenosis , and can be used for detecting the lesions in animal models of peripheral vascular diseases .
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Background: COPD is a preventable and treatable disease with some important extra pulmonary effects, which may contribute to the severity of this disease. Among these extra pulmonary ailments cardiovascular disorders are noteworthy. Although its silent involvement is known, but little attention paid to this major comorbidity while treating COPD patients. Objective: to assess rate, systolic blood pressure (SBP) and peak systolic velocity (PSV) of blood flow to observe the cardiovascular function status in stable COPD patients Methods: This cross-sectional study was carried out in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka during 2010. For this purpose 60 (sixty) male, smoker (5 to 10 pack years) patients of stable COPD (FEV1/FVC% <0.70; FEV1 e” 80%; without any exacerbation for last 4 weeks) were randomly selected from the Out Patient Department of the Department of Cardiology, BSMMU and also from a private clinic in Dhaka city. On the basis of spirometric findings, 30 mild (group B1) and 30 moderate stage (group B2) of COPD patients with age 35-45 years were included in the study. In addition, 30 age and BMI matched apparently healthy male persons were studied as control (group A). For assessment of cardiovascular function, pulse rate, SBP and PSV were measured. PSV of blood flow in distal part of the right brachial artery in arm was measured by Color Doppler ultrasonography. For statistical analysis, Independent sample t-test and Pearson’s Correlation Coefficient test were used. Results: Significantly (p<0.001) higher mean pulse rate and SBP were observed in moderate stage of COPD patients than those of control and mild stage. PSV was significantly (p<0.001) higher in both stages than those of the control as well as in moderate stage to that of the mild COPD. In addition, SBP and PSV were negatively correlated with FEV1 in moderate stage which was statistically significant (p<0.01). Conclusion: This study suggests that, cardiovascular status may be altered in stable COPD and this alteration is inversely related to the severity of the disease.
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Pyodermatitis-pyostomatitis vegetans (PD-PSV) is a rare, benign pustular and vegetating mucocutaneous dermatosis with a tendency to affect the oral mucosa and the skin of the groin and axilla. The cutaneous lesions begin as crusted erythematous papulopustules, which coalesce to form large vegetating plaques, usually in the axillae, genital area and scalp. PD-PSV is known to be frequently associated with inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease. We report a rare case of PD-PSV, which showed typical clinical and istopathological features, but was not accompanied by inflammatory bowel disease.
Subject(s)
Axilla , Colitis, Ulcerative , Crohn Disease , Groin , Inflammatory Bowel Diseases , Mouth Mucosa , Scalp , Skin , Skin DiseasesABSTRACT
Transfusion related acute lung injury (TRALI) is rare, but can sometimes lead to serious complication, and increases transfusion related mortality. We report on a case of a 21-year-old female with a femoral arterial rupture. Because of a massive hemorrhage, she was given nine units of packed red blood cell (RBC), nine units of fresh frozen plasma (FFP), and eight units of platelet. One hour after the end of blood transfusion, the patient experienced a sudden onset of dyspnea, tachypnea, cyanosis, and hypoxemia in the recovery room. Her breathing sounds were markedly decreased and bilateral diffuse crackles were detected. There were no signs of volume overload. A chest X-ray showed bilateral coarse alveolar infiltrates and a CT scan showed bilateral non-cardiogenic diffuse pulmonary edema with pleural effusion. Pressure support ventilation (PSV) and noninvasive positive pressure ventilation (NIPPV) were applied via a full-face CPAP mask after changing to prone position. She showed slow improvement, and achieved a full recovery over the next seven days.
Subject(s)
Female , Humans , Acute Lung Injury , Hypoxia , Blood Platelets , Blood Transfusion , Cyanosis , Dyspnea , Erythrocytes , Hemorrhage , Masks , Plasma , Pleural Effusion , Positive-Pressure Respiration , Prone Position , Pulmonary Edema , Recovery Room , Respiratory Sounds , Rupture , Tachypnea , Thorax , VentilationABSTRACT
Transfusion related acute lung injury (TRALI) is rare, but can sometimes lead to serious complication, and increases transfusion related mortality. We report on a case of a 21-year-old female with a femoral arterial rupture. Because of a massive hemorrhage, she was given nine units of packed red blood cell (RBC), nine units of fresh frozen plasma (FFP), and eight units of platelet. One hour after the end of blood transfusion, the patient experienced a sudden onset of dyspnea, tachypnea, cyanosis, and hypoxemia in the recovery room. Her breathing sounds were markedly decreased and bilateral diffuse crackles were detected. There were no signs of volume overload. A chest X-ray showed bilateral coarse alveolar infiltrates and a CT scan showed bilateral non-cardiogenic diffuse pulmonary edema with pleural effusion. Pressure support ventilation (PSV) and noninvasive positive pressure ventilation (NIPPV) were applied via a full-face CPAP mask after changing to prone position. She showed slow improvement, and achieved a full recovery over the next seven days.