Analgesic effect and safety of using an epidural analgesia pump versus an intravenous analgesia pump for uterine artery embolization in the treatment of uterine fibroids / 中国基层医药

Objective:To investigate the analgesic effect and safety of using an epidural analgesia pump versus an intravenous analgesia pump for uterine artery embolization in the treatment of uterine fibroids. Methods:Fifty patients with uterine fibroids undergoing uterine artery embolization admitted to The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University from January 2019 to December 2021 were included in this study. They were divided into an observation group and a control group ( n = 25/group). Patients in the observation group used an epidural analgesia pump for pain relief, while patients in the control group used an intravenous analgesia pump for pain relief. At 1, 6, 12, and 24 hours after surgery, pain severity was compared between the two groups using the Visual Analogue Scale. Comfort level was compared between the two groups using the Bruggemann Comfort scale. Before and after surgery, respiratory rate, heart rate, blood pressure, and adverse reactions were compared between the two groups. Results:At 1 hour after surgery, the Visual Analogue Scale score in the observation group was significantly lower than that in the control group [3.00 (2.00, 5.50) vs. 7.00 (6.00, 8.00), Z = -3.84, P < 0.05]. At 6, 12, and 24 hours after surgery, there was a significant difference in the Visual Analogue Scale score between the two groups (all P > 0.05). Within 24 hours after surgery, the use of opioid analgesics in the observation group was less than that in the control group [16.00% (4/25) vs. 88.00% (22/25), χ2 = 25.96, P < 0.001]. At 1 hour after surgery, the Bruggemann Comfort Scale score in the observation group was significantly higher than that in the control group [0.00 (0.00, 0.50) vs. 0.00 (0.00, 0.00), Z = 2.08, P < 0.05]. At 6, 12, and 24 hours after surgery, there was no significant difference in the Bruggemann Comfort Scale score between the two groups (all P > 0.05). After surgery, heart rate was significantly decreased in each group compared with before surgery (both P < 0.05). There were no significant differences in respiratory rate and mean arterial pressure between the two groups before and after surgery (both P > 0.05). There were no significant differences in the incidences of postoperative nausea, vomiting, and fever between the two groups (all P > 0.05). Conclusion:The epidural analgesia pump used for uterine artery embolization in the treatment of uterine fibroids has a better analgesic effect and provides more comfort and is safer than the intravenous analgesia pump. The former is worthy of clinical promotion.

Effect of Acupoint Sticking plus Cervical Plexus Block Anesthesia on Post-operative Pain after Subtotal Thyroidectomy / 上海针灸杂志

Objective To observe the effect of acupoint sticking plus cervical plexus block anesthesia on post-operative pain in patients undergone subtotal thyroidectomy.Method Sixty patients who were going to receive unilateral subtotal thyroidectomy were randomized into group A and group B, 30 cases in each group. Group A was intervened by acupoint sticking plus cervical plexus block anesthesia, while group B was by cervical plexus block anesthesia alone. The Visual Analogue Scale (VAS) scores under static and swallowing condition were recorded at 6 h, 12 h, 24 h, and 48 h after the operation. Tramadol hydrochloride tablets were given to help cease pain when static incision VAS>3, and the total dose and adverse reactions in 48 h after the operation were recorded.Result There were no significant differences in comparing the VAS scores at static and swallowing status between the two groups at 6 h, 12 h, 24 h, and 48 h after the operation (P>0.05). The total dose of Tramadol hydrochloride tablets used in 48 h after the operation was (110±55)mg in group A, versus (210±48)mg in group B, and the difference was statistically significant (P<0.05). There was a significant difference in comparing the occurrence rate of adverse events in 48 h after the operation between the two groups (P<0.05).Conclusion Acupoint sticking plus cervical plexus block anesthesia can effectively alleviate the pain after subtotal thyroidectomy, reduce the use of analgesics in 48 h after the operation, and lower the occurrence rate of post-operative adverse events.

Avaliação da eficácia da analgesia preemptiva na cirurgia de extração de terceiros molares inclusos / Assessment of preemptive analgesia efficacy in surgical extraction of third molars / Evaluación de la eficácia de la analgesia de prevención en la cirugía de extracción de terceros molares incluidos

JUSTIFICATIVA E OBJETIVOS: A literatura sobre analgesia preemptiva é controversa. A confiabilidade dos resultados e a dificuldade de reprodutibilidade das pesquisas contribuem para a não elucidação do tema. O objetivo desse estudo é testar a eficácia da administração preemptiva de Cetoprofeno 150 mg via oral dois dias antes da cirurgia de extração deterceiros molares, comparando no mesmo paciente com a administração pós-operatória. MÉTODO: Treze pacientes foram submetidos à cirurgia de extração bilateral de terceiros molares inferiores inclusos em dois procedimentos distintos. De forma randomizada e duplo cega, em um procedimento foi administrado Cetoprofeno 150 mg via oral a cada 12 horas dois dias antes da cirurgia e, após o procedimento, continuou-se o mesmo medicamento por mais três dias. De outro lado, foi utilizado um controle (placebo) via oral a cada 12 horas dois dias antes da cirurgia e, após o procedimento, continuou-se o Cetoprofeno 150 mg a cada 12 horas por mais três dias. A dor pós-operatória foi avaliada por meio da escala visual analógica, da escala nominal e da quantidade de consumo de analgésicos de resgate. RESULTADOS: Não foi observada diferença estatisticamente significante na dor pós-operatória entre o tratamento preemptivo e o controle. CONCLUSÃO: Neste modelo experimental, a analgesia preemptiva não se mostrou eficaz na redução da dor pós-operatória na cirurgia de extração de terceiros molares inclusos em comparação com a administração pós-operatória do mesmo medicamento.

BACKGROUND AND OBJECTIVES: Literature on preemptive analgesia is controversial. Reliability of results and difficult reproducibility of research contribute for non-elucidation of the subject. The aim of this study is to test the efficacy of oral ketoprofen (150 mg) preemptively administrated two days before third molar surgery, compared with postoperative administration in the same patient. METHODS: Thirteen patients underwent surgical removal of bilateral third molar in two separate procedures. In a random and double blind procedure, oral ketoprofen 150 mg was administered every 12 hours two days before surgery and, after the procedure, the same drug was administered for three days. On the other side, a control (placebo) was used orally every 12 hours two days before surgery and, after the procedure, ketoprofen 150 mg was administered every 12 hours for three days. Postoperative pain was assessed by visual analogue scale, nominal scale, and amount of rescue analgesics consumed. RESULTS: There was no statistically significant difference in postoperative pain between the preemptive treatment and control. CONCLUSION: In this experimental model, preemptive analgesia was not effective in reducing postoperative pain in surgical extraction of third molar compared with the postoperative administration of the same drug.

JUSTIFICATIVA Y OBJETIVOS: La literatura sobre la analgesia de prevención es controversial. La confiabilidad de los resultados y la dificultad de reproductibilidad de las investigaciones contribuyen para que el tema no quede clarificado en su totalidad. El objetivo de este estudio, es comprobar la eficacia de la administración de prevención del Cetoprofeno 150 mg por vía oral dos días antes de la cirugía de terceros molares, comparando al mismo paciente con la administración postoperatoria. MÉTODO: Trece pacientes se sometieron a la cirugía de extracción bilateral de terceros molares inferiores incluidos en dos procedimientos distintos. De forma randomizada y doble ciega, en un procedimiento se administró Cetoprofeno 150 mg por vía oral a cada 12 horas dos días antes de la cirugía y después del procedimiento continuamos con el mismo medicamento por tres días más. Por otra parte, fue utilizado un control (placebo) vía oral a cada 12 horas dos días antes de la cirugía y después del procedimiento se continuó con el Cetoprofeno 150 mg a cada 12 horas por tres días más. El dolor del postoperatorio, se evaluó por medio de la escala visual analógica, de la escala nominal y de la cantidad de consumo de analgésicos de rescate. RESULTADOS: No se observaron diferencias estadísticamente significativas en el dolor postoperatorio entre el tratamiento de prevención y el control. CONCLUSIONES: En este modelo experimental, la analgesia de prevención no fue eficaz en la redución del dolor postoperatorio en la cirugía de extracción de terceros molares incluidos en comparación con la administración postoperatoria del mismo medicamento.

Intensidad y manejo del dolor posoperatorio en pacientes hospitalizados / Intensity and management of postoperative pain in hospitalized patients

Introducción: Identificar la intensidad y manejo del dolor posoperatorio; además de explorar diferencias en la intensidad del dolor de acuerdo al sexo y su asociación con edad y escolaridad del paciente, así como según el entrenamiento para el manejo del dolor por personal de enfermería y pacientes asignados por turno en una muestra de 151 adultos hospitalizados en una institución de seguridad social de Nuevo León, México. Materiales y Métodos: Diseño descriptivo, incluyó encuesta por muestreo sistemático. Resultados: Se encontró que el 90.1% de los participantes presentó dolor posoperatorio, 57.6% manifestó intensidad de dolor severo en las primeras 24 horas y 28.5% recibió un manejo de dolor inadecuado. Únicamente se encontró diferencia significativa en la intensidad del dolor de acuerdo al sexo (U = 1799, p = .006) con predominio en las mujeres. Discusión y Conclusiones: Es urgente implementar protocolos para el manejo del dolor posoperatorio, que incluyan la participación del equipo multidisciplinario y consideren el tratamiento farmacológico con potencia adecuada de acuerdo a la demanda del paciente y la valoración del dolor de manera regular, principales áreas de oportunidad identificadas en el presente estudio.

Introduction: To determine the intensity and management of postoperative pain. We explored the differences according to age, sex and education of patients and in relation to the nursing staff’s training in pain management and the patients assigned per shift. Materials and Methods: The descriptive design included a survey by systematic sampling, using a sample of 151 adults hospitalized in a Nuevo Leon, México, social security institution. Results: We found that 90.1% of the participants presented postoperative pain, 57.6% expressed severe pain intensity in the first 24 hours and 28.5% received inappropriate pain management. Only one significant difference in the pain intensity was found according to sex (U = 1799, p = .006), predominantly in women. Discussion and Conclusions: We concluded it is urgent to implement postoperative pain management protocols that involve the participation of a multidisciplinary team, and consider pharmacological treatment with appropriate power according to patient demand and pain assessment regularly, identified key areas of opportunity in the present study.

Registros sobre dor pós-operatória em crianças: uma análise retrospectiva de hospitais de Londrina, PR, Brasil / Registros sobre el dolor post operatorio en niños: un análisis retrospectivo en hospitales de Londrina, PR, Brasil / Notes of post-operative pain in children: a retrospective analyses of hospitals from Londrina, PR, Brazil

Toda cirurgia implica em lesão de tecidos, manipulação de estruturas e órgãos, sendo a dor uma conseqüência desse processo, que pode ser minimizada. Este estudo tem como objetivo caracterizar, retrospectivamente, o processo de manejo da dor pós-operatória a partir dos registros contidos em 300 prontuários de 280 crianças de 0 a 14 anos submetidas à cirurgia no ano de 2004 em três hospitais de Londrina, PR. O estudo indicou a existência de poucos registros sobre dor pós-operatória realizados por enfermeiras, sendo a maioria realizada por auxiliares ou técnicos de enfermagem. Esses achados evidenciam a necessidade de realização de pesquisas sobre manejo da dor pediátrica e os fatores que o influenciam.

All surgical procedures involve tissue lesions, manipulation of structures and organs, causing pain which can be minimized during the process. The objective of this study is to characterize, retrospectively, the process of managing post-operative pain based on 300 medical records of 280 childre, who underwent surgery in 2004, in 3 hospitals located in Londrina, PR, Brazil. The study revealed that only a few nurses document post-operative pain, and that the majority of the records were made by nursing aides or technicians. The results have shown the need for research on pediatric pain management and the factors affecting them.

Toda cirugía implica en lesión de tejidos, manipulación de estructuras y órganos, siendo el dolor una consecuencia de ese proceso, que puede ser minimizada. El presente estudio tiene como objetivo caracterizar, retrospectivamente, el proceso del manejo del dolor pos operatorio a partir de los registros contenidos en 300 prontuarios de 280 niños de 0 a 14 años sometidos a cirugía el año 2004 en tres hospitales de Londrina, PR, Brasil. El estudio indicó la existencia de pocos registros realizado por enfermeras, y la mayoría fue realizada por auxiliares o técnicos de enfermería. Los resultados evidencian la necesidad de la realización de pesquisas sobre el manejo del dolor pediátrico y los factores que lo influencian.