ABSTRACT
Nutritional anaemia is frequently observed in India. Prevalence of anaemia in Indian children is 59% (Hb<11gm/dl) but it’s higher among rural children. Iron deficiency is most common type nutritional deficiency anaemia in children. The nearest correlation of iron deficiency anemia (IDA) can be made with Pandu Roga in Ayurveda. The side effects of oral allopathic iron preparations are very common, therefore to get a better alternative, two Ayurvedic medicines, the Guda Haritaki and Punarnava Mandura, were subjected to a clinical trial among children suffering from IDA. Aim: Determine the role of Guda Haritaki and Punarnava Mandura in the management of Pandu roga w.s.r. to iron deficiency anaemia among children. Materials and Methods: The study was conducted on 35 children of IDA for a period of 6 weeks. Clinical features (Panduta, Daurbalya etc.) and hematological parameters (Hb gm %, sr. ferritin etc.) were documented before, during and after treatment. Statistical Analysis Used: Observations of the study were analyzed and findings were evaluated by using statistical methods Results: In the present study 58.82% improvement in Panduta was observed with Guda haritaki, 65% with Punarnava Mandura and 67 % when both drugs were given together. No adverse effect of the trial drug was observed during the study. Conclusions: The results suggest that Punarnava mandura along with Guda Haritaki is more effective in comparison to single use of either formulation in the management of IDA in children.
ABSTRACT
Background: The prevalence of anaemia in general and iron deficiency anaemia in particular is presently rising in the society. The primary objective of this study was to determine the prevalence of anaemia among school going children in rural and semi urban areas of Kangra district (Himachal Pradesh). Secondary objective was to identify the etiological and contributory factors in anaemia on the basis of Ayurvedic fundamentals. Methods: A population of 200 children studying in different schools of rural and semi urban areas of Kangra district Himachal Pradesh and IPD as well as OPD of department of Kaumarbhritya, R.G.G. P.G. Ayurvedic college and hospital Paprola were included in the survey. The data obtained from the survey was evaluated to assess the prevalence of anemia and its correlates. To fulfill the aims and objectives a specially prepared performa was designed and all details of the children were recorded in it. Results: The prevalence of anaemia was found to be 69% in school going children in rural areas of Kangra district, Himachal Pradesh. The major risk factors which were observed in present study were nutrition, socio-economic status, pica and dewormification. Conclusion: Anaemia is comparatively more common among children of semi urban and rural areas of Himachal Pradesh possible due to multiple factors like low socioeconomic status, menstruation and inadequate diet etc.
ABSTRACT
Pandu means pallor. In this disease there is predominance of paleness all over the body. due to its similarity it can be co-related with modern disease anaemia. Pandu Roga is explained by almost all of our Acharyas. This article is based on Nidanapanchaka of Pandu Roga from Ayurvedic texts as Charak samhita, Susruta samhita, Astanga hrudaya etc with all commentaries. Rasavaha and Raktavaha srotas are chiefly involved in pathogenesis of Pandu Roga. The changing lifestyle of human being by means of Ahara and Vihar plays a major role in manifestation of various diseases. Pandu Roga is also one of them. Our faulty dietary habits and lifestyle produces Ama which further causes Agnimandya and ultimately Amayukta Ahararasa produced. It hampers Rasa Dhatu utpatti and manifests Pandu Roga. Aggravated Pitta is responsible for the production of Posaka (nutrient portion) from the Rasadhatu as a result depletion of Rakta takes place. The detail knowledge of Nidanapanchaka and types of Pandu Roga will help in its diagnosis and management in this modern era also.
ABSTRACT
Context: Nutritional iron deficiency is the most common cause of anemia in India. The nearest correlation of iron deficiency anemia (IDA) can be made with Pandu Roga in Ayurveda. As the IDA is a very common prevalent disease in the society and the side effects of oral allopathic iron preparations are very common, therefore to get a better alternative, an Ayurvedic herbomineral medicine, the Trikatrayadi Lauha, was subjected to a clinical trial in children suffering from IDA. Aim: Evaluation of safety and efficacy of the compound Trikatrayadi Lauha suspension in children with IDA. Settings and Design: Randomized, double-blind placebo-controlled clinical study. Materials and Methods: The study was conducted on 123 children of IDA for a period of 10 weeks. Clinical features and hematological parameters were documented before, during and after treatment. Statistical Analysis Used: Observations of the study were analyzed and findings were evaluated by using statistical methods (Student's t test) Results: The present study shows that the trial drug Trikatrayadi Lauha suspension is effective to improve clinical features and hematological parameters significantly. The medicine is effective to increase the hemoglobin level 1.94 g/dL (8.52 -10.46 g/dL, P < 0.001) in 5 weeks and 3.33g/dL (8.52 -11.85g/dL, P < 0.001) in 10 weeks. No adverse effect of the trial drug was observed during the study. Conclusions: The results suggest that Trikatrayadi Lauha is significantly effective in the management of IDA in children.