ABSTRACT
Resumen: La necesidad de distanciamiento social impuesta por la actual pandemia por coronavirus obligó a las diferentes sociedades científicas a realizar sus actividades en formato completamente virtual. La Sociedad Europea de Cardiología no ha sido la excepción. Desde el 29 de agosto al 1 de septiembre de 2020 se celebró este evento sin precedentes que, además de contar con 125.000 profesionales de 213 países, permitió el acceso gratuito a todos los cibernautas. De esta manera, la actualidad en cardiología pudo llegar a todos los rincones del mundo, pese a las circunstancias tan complejas. Como ya es tradición de la revista, realizamos un resumen de los principales ensayos presentados durante el congreso: - Early Rhythm-Control Therapy in Patients with Atrial Fibrillation (EAST-AFNET 4) - Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure (The EMPEROR-Reduced Trial Investigators) - Efficacy and Safety of Mavacamten in Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy (EXPLORER-HCM) - Angiotensin Receptor Neprilysin Inhibition Compared with Individualized Medical Therapy for Comorbidities in Patients with Heart Failure and Preserved Ejection Fraction (The PARALLAX Trial) - A Study to Evaluate the Effect of Dapagliflozin on Renal Outcomes and Cardiovascular Mortality in Patients with Chronic Kidney Disease (DAPA-CKD) - Aspirin with or without Clopidogrel after Transcatheter Aortic-Valve Implantation (POPULAR TAVI (Cohort A)) - Colchicine in Patients with Chronic Coronary Disease (The LoDoCo2 Trial Investigators) - Pharmacological Blood Pressure-Lowering for Primary and Secondary Prevention of Cardiovascular Disease Across Different Levels of Blood Pressure (BPLTTC) - Continuing versus suspending angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: Impact on adverse outcomes in hospitalized patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (The BRACE CORONA Trial) - Randomized Trial of Transfusion Strategies in Patients with Myocardial Infarction and Anemia (REALITY Trial)
Summary The need for social distancing imposed by the current coronavirus pandemic, forced the different scientific societies to carry out their activities in a completely virtual format. And the European Society of Cardiology has not been the exception. From August 29 to September 1 of 2020, this unprecedented event was held which, in addition to having 125,000 health professionals from 213 countries, allowed free access to all netizens. In this way, current affairs in cardiology could reach all corners of the world, despite such complex circumstances. As is the tradition of the magazine, we present a summary of the main essays presented during the congress: - Early Rhythm-Control Therapy in Patients with Atrial Fibrillation (EAST-AFNET 4) - Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure (The EMPEROR-Reduced Trial Investigators) - Efficacy and Safety of Mavacamten in Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy (EXPLORER-HCM) - Angiotensin Receptor Neprilysin Inhibition Compared with Individualized Medical Therapy for Comorbidities in Patients with Heart Failure and Preserved Ejection Fraction (The PARALLAX Trial) - A Study to Evaluate the Effect of Dapagliflozin on Renal Outcomes and Cardiovascular Mortality in Patients with Chronic Kidney Disease (DAPA-CKD) - Aspirin with or without Clopidogrel after Transcatheter Aortic-Valve Implantation (POPULAR TAVI (Cohort A)) - Colchicine in Patients with Chronic Coronary Disease (The LoDoCo2 Trial Investigators) - Pharmacological Blood Pressure-Lowering for Primary and Secondary Prevention of Cardiovascular Disease Across Different Levels of Blood Pressure (BPLTTC) - Continuing versus suspending angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: Impact on adverse outcomes in hospitalized patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (The BRACE CORONA Trial) - Randomized Trial of Transfusion Strategies in Patients with Myocardial Infarction and Anemia (REALITY Trial)
Resumo A necessidade de distanciamento social imposto pela atual pandemia do coronavírus, obrigou as diferentes sociedades científicas a desenvolverem suas atividades de forma totalmente virtual. E a Sociedade Europeia de Cardiologia não foi exceção. De 29 de agosto a 1º de setembro 2020, foi realizado esse evento inédito que, além de contar com 125.000 profissionais de saúde de 213 países, possibilitou o acesso gratuito a todos os internautas. Dessa forma, a atualidade da cardiologia pode atingir todos os cantos do mundo, apesar de circunstâncias tão complexas. Como é tradição da revista, apresentamos um resumo dos principais ensaios apresentados durante o congresso: - Early Rhythm-Control Therapy in Patients with Atrial Fibrillation (EAST-AFNET 4) - Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure (The EMPEROR-Reduced Trial Investigators) - Efficacy and Safety of Mavacamten in Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy (EXPLORER-HCM) - Angiotensin Receptor Neprilysin Inhibition Compared with Individualized Medical Therapy for Comorbidities in Patients with Heart Failure and Preserved Ejection Fraction (The PARALLAX Trial) - A Study to Evaluate the Effect of Dapagliflozin on Renal Outcomes and Cardiovascular Mortality in Patients with Chronic Kidney Disease (DAPA-CKD) - Aspirin with or without Clopidogrel after Transcatheter Aortic-Valve Implantation (POPULAR TAVI (Cohort A)) - Colchicine in Patients with Chronic Coronary Disease (The LoDoCo2 Trial Investigators) - Pharmacological Blood Pressure-Lowering for Primary and Secondary Prevention of Cardiovascular Disease Across Different Levels of Blood Pressure (BPLTTC) - Continuing versus suspending angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: Impact on adverse outcomes in hospitalized patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (The BRACE CORONA Trial) - Randomized Trial of Transfusion Strategies in Patients with Myocardial Infarction and Anemia (REALITY Trial)
ABSTRACT
Este trabalho toma, como chave de leitura para a obra Em busca do tempo perdido, de Marcel Proust, a função desempenhada pelos instrumentos ópticos à luz do conceito de paralaxe. Em nossa leitura da obra de Proust, a incidência da mudança de posição do observador sobre a percepção do fenômeno dialoga com os conceitos de realidade psíquica (Freud) e Real (Lacan). Os instrumentos ópticos, entre os quais a própria obra, servem antes para deformar do que como meio de acesso ao mundo. Assim, a realidade psíquica não provém de dados perceptivos, mas de constante releitura.
This paper analyses the function of optical instruments, in light of the concept of parallax, as keys to read Marcel Proust's novel In Search of Lost Time. In our reading of Proust's work, the influence of the observer's change of position on the perception of the phenomenon produces a dialogue with the concepts of psychic reality (Freud) and real (Lacan). Optical instruments, including the novel itself, serve to deform rather than to access the world. Thus, psychic reality doesn't come from perceptual data, but from constant rereading.
Ce travail prend comme clé de lecture de À la recherche du temps perdu, de Marcel Proust, le rôle joué par les instruments optiques, conçu à la lumière de la notion de parallaxe. Dans notre lecture de l'œuvre de Proust, l'incidence du changement de position de l'observateur sur la perception du phénomène produit un dialogue avec les concepts de réalité psychique (Freud) et réel (Lacan). Les instruments optiques, y compris le travail de la littérature, servent à déformer le monde plutôt qu'à y accéder. Ainsi, la réalité psychique ne provient pas de données perceptuelles, mais de constante réinterprétation.
Para la lectura de la obra En busca del tiempo perdido, de Marcel Proust, este trabajo se basa en la función desempeñada por los instrumentos ópticos a la luz del concepto de paralaje. En nuestra lectura de la obra de Proust, la incidencia del cambio de posición del observador, sobre la percepción del fenómeno, dialoga con los conceptos de realidad psíquica (Freud) y real (Lacan). Los instrumentos ópticos, incluyendo la obra en sí, antes de ser un medio de acceso al mundo sirven para deformar. De esta forma, la realidad psíquica no proviene de datos percibidos, sino de una reinterpretación constante.
Diese Arbeit analysiert die Funktion der optischen Instrumente gemäß dem Konzept der Parallaxe und benutzt diese als Schlüssel zu Marcel Prousts Hauptwerk Auf der Suche nach der verlorenen Zeit. Wir vertreten den Standpunkt, dass ein Dialog zustande kommt zwischen der Positionsänderung des Betrachters bezüglich der Wahrnehmung des Phänomens und die Begriffe der psychischen Realität (Freud) und des Realen (Lacan). Optische Instrumente, zu denen das literarisches Werk selbst zählt, dienen eher dazu, die Welt zu deformieren als dass sie einen Zugang zu ihr verschaffen. So entsteht die psychische Realität nicht aufgrund von Wahrnehmungsdaten, sondern aus wiederholtem lesen.
ABSTRACT
To determine the amount of displacement of a structurenoticed on an image when the tube of a dental X-raymachine was shifted vertically and horizontally. Inaddition, various intraoral images were combined withdental panoramic images to determine the location ofstructures. Our research is based on the parallaxtechnique which requires manipulation of horizontaland vertical angulations of the X-ray tube. A metalobject is positioned on the buccal and palatal side ofthe maxilla on the canine area of a skull. The X-raytube is shifted incrementally to obtain images onphosphor plates. Subsequently, panaromic and occlusalimages were taken to assist in localization of the metalobject. To obtain a clear image shift of 2-3mm usingthe parallax method, there must be an adequatehorizontal tube shift of approximately 30-35 degrees.When images were used in combination of dentalpanoramic images, it was found that the buccallyplaced structures can be accurately located with theperiapical or occlusal images. However, thedisplacement of images in the palatally placedstructures in panoramic imaging is not fullyappreciated with the principle of parallax method. Tubemovement of 30-35 degrees horizontally is needed fora 2-3 mm image shift. To successfully localize a buccalstructure, a combination of either periapical or occlusalimages with a dental panoramic imaging can beemployed. However, this combination with panoramicimaging is limited when looking at palatally placedstructures.
ABSTRACT
BACKGROUND AND OBJECTIVES: The vestibulo-ocular reflexes (VOR) act a short latency to optimize vision during locomotion. The angular VOR (aVOR) has been widely studied in human subjects and preserves clear, stable vision during rotational head perturbations by generating eye movements that hold the line of sight on the target of interest. Less is known about the properties of the linear or translational VOR (tVOR), mainly due to technical difficulties posed by testing head or body translations. Geometric considerations indicate that different properties should be expected of tVOR, which can only provide stable vision of objects lying in one depth plane. MATERIALS AND METHODS: We studied the human tVOR using a moving platform to translate normal human subjects vertically at frequencies similar to those occurring during locomotion. We found that, whereas aVOR is concerned with holding retinal images fairly stable to optimize clear vision, tVOR seems best suited to minimize relative motion of retinal images belonging to objects lying in different depth planes-and thereby to optimize motion parallax information. We also investigated whether the tVOR functioned abnormally in patients with neurological disorders causing falls-progressive supranuclear palsy (PSP) and cerebellar ataxia. RESULTS: Both groups of patients showed impaired ability to modulate their tVOR during viewing of near targets; in PSP this might be attributed to failure of convergence, but cerebellar patients failed to modulate tVOR at near despite intact convergence. CONCLUSION: In both disorders, an impaired ability to adjust tVOR for viewing distance points to central disturbance of otolithic vestibular reflexes, which may also contribute to postural instability.