ABSTRACT
Background: This study was conducted to assess the role of Partial Parenteral Nutrition (PPN) and a specially prepared 'mixed fluid formula' used as PPN in sick surgical neonates.Methods: This single institution based Randomised Control Trial was performed in Surgical NICU of a tertiary care Centre. Surgical neonates who required bowel rest for >3 days like Esophageal Atresia (22), Duodenal Atresia (38), Jejuno-Ileal Atresia (50), Necrotising Enterocolitis (29) and others (11), were chosen. As a CONTROL population half (75) neonates were allowed maintenance fluid only (Isolyte P) and rest (75) were given a combination of maintenance fluid (Isolyte P) and PPN (specially prepared mixed fluid). This mixed fluid each 100 ml was prepared with 65ml Isolyte P, 15 ml 25% Dextrose, 10 ml Normal Saline, 7 ml Astymin 3, 2 ml Multivitamin and 1 ml Injection KCl. Fluid was continued till enteral feeding was established.Results: Neonates according to their body weight were divided in three groups <1 kg (50), 1-2.5 kg (71) and >2.5 kg (29) and their post-operative outcome was assessed as Clinical Positive/Negative and Laboratory Positive/Negative. Results were separately assessed in 3 body weight groups under 'Control' and 'Study' which showed both Clinical and Biochemical improvement in 'Study group'.Conclusions: The composition of mixed fluid, its nutritional value, calorie supplementation, compatible osmolarity for peripheral venous administration and most importantly its easy and cost-effective preparation were assessed thoroughly and we recommend this 'mixed fluid' preparation as a very useful PPN for sick surgical neonates.
ABSTRACT
Objective To study the effect of partial parenterai nutrition support in severe cases of general surgery.Methods Treated 170 severe cases from January 2001 to September 2008,ran two sets, 80 cases of ex-perimental group and 90 cases of the control group.Results The exaltation of hemoglobin, albumin, lymphocytes and weight in experimental group were better than those in the control group (P < 0.05).The level of glycemic control was also better than that in the control group (P < 0.05).Conclusions The effection of partial parenteral nutrition support is reliable, practical and low-cost.
ABSTRACT
Nine patients with neonatal malabsorption syndrome and low birth weight infants were treated with PPN support. 10 cases of newborns were as control. The results showed that increases in weekly average body weight and plasma albumin after treatment were higher in the therapeutical group than in control group ( P