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Objective: To investigate the clinical features and long-term prognosis of primary biliary cholangitis (PBC) in patients with past hepatitis B virus (HBV) infection. Methods: 353 cases with PBC who visited the Liver Disease Center of Beijing Friendship Hospital Affiliated to Capital Medical University between January 2000 and January 2018 were retrospectively analyzed and were divided into the past HBV infection group (156 cases) and the no HBV infection group (197 cases). The two groups' baseline clinical features were compared. Ursodeoxycholic acid response rate after one year, GLOBE score, UK-PBC score, and long-term liver transplantation-free survival rate were compared through outpatient and telephone follow-up. Results: PBC with past HBV infection had a significantly reduced female proportion compared to the no HBV infection group (91.9% vs. 79.5%, P = 0.001). However, there were no statistically significant differences in age, biochemical indices, immunological indicators, platelet count, cirrhosis proportion, and others. Ursodeoxycholic acid biochemical response rate was reduced in patients with past HBV infection at the end of one year of treatment, but the difference was not statistically significant (65.8% vs. 78.2%, P = 0.068). In addition, there were no statistically significant differences between the GLOBE score (0.57 vs. 0.59, P = 0.26) and UK-PBC 5-year (2.87% vs. 2.87%, P = 0.38), 10-year (9.29% vs. 8.2%, P = 0.39) and 15-year liver transplantation rates (16.6% vs. 14.73%, P = 0.39). Lastly, the overall 5-year liver transplantation-free survival rate had no statistically significant difference between the two groups of patients (86.4% vs. 87.5%, P = 0.796). Conclusion: Primary biliary cholangitis had no discernible effect in terms of age at onset, biochemical indices, immunological indicators, cirrhosis proportion, ursodeoxycholic acid response rate after one year, GLOBE score, UK-PBC score, or overall liver transplantation-free survival rate in patients with past hepatitis B virus infections.
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Objective:To analyze the endoscopic characteristics of early gastric cancer and precancerous lesions after Helicobacter pylori ( H. pylori) eradication. Methods:From May 2019 to June 2022, at Shanghai Sixth People′s Hospital affiliated to Shanghai Jiaotong University School of Medicine, the medical data of patients diagnosed with differentiated early gastric cancer and precancerous lesions were collected. A total of 93 patients with early gastric cancer and precancerous lesions who had previous history of H. pylori infection and had undergone standardized eradication treatment were selected, and their endoscopic characteristics were retrospectively analyzed. Independent sample t-test, chi-square test, and Fisher′s exact test were used for statistical analysis. Results:Among 93 patients with early gastric cancer and precancerous lesions after H. pylori eradication, there were 56 males and 37 females, with an average age of (66.9±8.2) years old. The time after H. pylori eradication was 3.4 years (range 1.0 to 7.0 years). A total of 109 early gastric cancer and precancerous lesions were found, including 79 patients with single lesion and 14 patients with multiple lesions (30 lesions). There were 60 cases with 73 lesions in the early gastric cancer group and 33 cases with 36 lesions in the precancerous group. Among 93 patients, 89 cases (95.7%) were diagnosed with atrophy level above C-2 according to Kimura-Takemoto classification under endoscopy. The long diameter of 109 lesions was (1.38±0.70) cm and the short diameter was (1.04±0.53) cm. A total of 80 lesions (73.4%) were located in the lower 1/3 part of the stomach, and 53 lesions (48.6%) were located in the lesser curvature. A total of 106 lesions (97.2%) were superficial type (0-Ⅱ) under the endoscopy. The long diameter and short diameter in the early gastric cancer group after H. pylori eradication were both greater than those in the precancerous lesion group ((1.54±0.78) cm vs. (1.06±0.35) cm, (1.16±0.58) cm vs. (0.78±0.33) cm), and the differences were statistically significant ( t=3.53 and 3.73, both P<0.001). There was statistically significant difference in the morphological types between early gastric cancer group after H. pylori eradication and precancerous lesion group ( χ2=11.01, P=0.012). The main morphological type of early gastric cancer after H. pylori eradication was superficial depression type (0-Ⅱc), accounting for 45.2% (33/73), while the precancerous lesions were mainly superficial protruded and flat type, both accounting for 38.9% (14/36). Conclusions:After H. pylori eradication, the endoscopic atrophy range of early gastric cancer and precancerous lesions is mostly above C-2. And the lesions are mostly located in the middle and lower 1/3 part of the stomach, long diameter of lesions <20 mm. The main morphological type is superficial type, especially superficial depression type.
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O presente artigo teve como objetivo compreender a história pregressa da criança e o processo de revelação da adoção na perspectiva de pais adotivos. Trata-se de uma pesquisa de campo, qualitativa, descritiva e exploratória, que utilizou como método o estudo de caso. Foram realizadas entrevistas semiestruturadas com duas mães e um pai adotivos. Os dados foram analisados por meio da análise do conteúdo de Minayo. Observou-se que as histórias das crianças e/ou o acesso dos pais a essas, mostraram-se com questões muito particulares, mediante a disponibilidade dos órgãos de proteção em passar informações sobre esse passado. A maioria dos pais demonstrou interesse em revelar a adoção, entretanto, a questão apareceu vinculada a insegurança, posto que, além de não terem tido acesso a informações sobre a história pregressa de seus filhos, os pais demonstraram dificuldades em lidar com o passado da criança, dados que revelam a importância do psicólogo para auxiliar adotantes na elaboração de conteúdos vinculados a experiência adotiva, dentre eles, suas próprias angustias vinculadas ao medo de perder seu filho, em virtude da camuflagem: família biológica x família adotiva.
This article aimed to understand the child's past history and the process of revelation of adoption from the perspective of adoptive parents. It is a research field qualitative, descriptive and exploratory, which used the case study as a method. Semi-structured interviews were conducted with two adoptive mothers and fathers. The results were analyzed through of the analysis of the content of Minayo. It was observed that the children's stories and/or the parents' access to them, showed themselves with very particular issues, due to the availability of the protection organs, associated with the cases, to pass on information about this past. Most parents showed interest in revealing the adoption, however, the issue was linked to insecurity, since, in addition to not having access to information about their children's previous story, parents showed difficulties in dealing with the child's past, data that reveal the importance of the psychologist to assist adopters in the elaboration of contents linked to the adoptive experience, among them, yours anxieties linked to the fear of losing their child, due to the camouflage: biological family x adoptive family.
Buscamos entender cómo los padres adoptivos significan la historia pasada de los niños y su revelación. Se trata de una investigación de campo cualitativa, descriptiva y exploratoria, que utilizó el estudio de caso como método. Se realizaron entrevistas semiestructuradas con dos madres y padres adoptivos. Los datos fueron analizados a la luz del análisis del contenido de Minayo. Se observó que las historias de los niños y/o el acceso de los padres a ellas, se mostraron con problemáticas muy particulares, debido a la disponibilidad de los órganos de protección, asociados a los casos, para transmitir información sobre este pasado. La mayoría de los padres mostraron interés en revelar la adopción, sin embargo, el problema parecía estar relacionado con la inseguridad, ya que, además de no tener acceso a información sobre la historia pasada de sus hijos, los padres demostraron dificultades para lidiar con el pasado del niño, datos que revelan la importancia del psicólogo para ayudar a los adoptantes en la elaboración de contenidos vinculados a la experiencia adoptiva, entre ellos, sus propias ansiedades ligadas al miedo a perder a su hijo, debido al camuflaje: familia biológica x familia adoptiva.
Subject(s)
Humans , Child , Truth Disclosure , Family Relations , Father-Child RelationsABSTRACT
Resumen: Las políticas de memoria han sido estudiadas desde las ciencias sociales principalmente en ámbitos institucionales, siendo escaso su abordaje desde la cotidianidad. Este artículo contribuye a ello presentando resultados de una investigación que buscó comprender la construcción de memorias del pasado reciente de Chile (1970-1990) y sus efectos políticos desde la cotidianidad de jóvenes. Se realizaron entrevistas a 33 jóvenes de diferentes niveles socioeconómicos, posiciones ideológicas y vínculos en relación al conflicto de represión política vivido durante la dictadura militar. Desde el material analizado discursivamente, se evidencia que, para las/os jóvenes, las conversaciones familiares son espacios fundamentales para hacer memoria, donde su posición es considerada como una voz poco legítima para recordar un pasado no vivido directamente. Asimismo, los recuerdos que configuran se caracterizan por su carácter fragmentario y su vínculo con la cotidianidad. Se concluye que si bien lo anterior ha implicado despolitizar la memoria, potencialmente ha instalado también su politización.
Resumo: As políticas da memória têm sido estudadas apartir das ciências sociais principalmente em ambientes institucionais, mas, a sua abordagem na vida cotidiana é escassa. Este artigo contribui para isso, ao apresentar os resultados de uma pesquisa que procurou compreender a construção das memórias do passado recente do Chile e os seus efeitos políticos a partir do cotidiano dos jovens. Foram realizadas entrevistas com 33 jovens de diferentes níveis socioeconômicos, posições ideológicas e vínculos em relação ao conflito de repressão política experimentado na ditadura militar. A partir do material analisado discursivamente, fica evidente que, para os jovens, as converções com os familiares são espaços fundamentais para fazer memória, onde a sua posição é mediada por ser considerada uma voz pouco legítima para relembrar um passado não experimentado diretamente. Da mesma forma, as memórias que constituem são caracterizadas pela fragmentação e pela ligação com o quotidiano. Conclui-se que embora o acima tenha implicado em despolitizar a memória, potencialmente também instala a sua politização.
Abstract: Memory politics have been studied from the social sciences mainly in institutional environments, but their approach in everyday life perspective is scarce. This article contributes to this perspective by presenting the results of a study that sought to understand the construction of memories of Chile's recent past (1970-1990) and its political effects from the daily lives of young people. Interviews were carried out with 33 young people selected from different socioeconomic levels, ideological positions and ties in relation to the conflict of political repression experienced during the military dictatorship. From the discursively analyzed material, it is evident that, for young people, conversations with family members are fundamental spaces for making memory, where their position is mediated by being considered not a legitimate voice to remember a past not directly experienced by them. In the same way, the memories built by young people are characterized by fragmentation and connection with everyday life. It is concluded that although the above has implied in depoliticizing memory, it also potentially installs its politicization.
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Health and longevity are the eternal themes of human pursuit. The pre-Qin period was the beginning of the development of traditional health preservation. Combined with archaeological findings and relevant literature and materials, this paper summarizes the behaviors and phenomena related to health preservation in the pre-Qin period from the three aspects, namely, exercise, diet, and environment and personal health. Through long-term investigation from the perspective of medical archaeology, the development of pre-Qin health concept can be roughly divided into three stages: prehistoric period; Xia, Shang, Western Zhou period; and Eastern Zhou dynasties. It is mainly manifested as from unconsciousness to consciousness and from simple experience accumulation stage to the exploration and summary of theory. It is closely related to the improvement of social productivity and the development of medicine and ancient philosophy, which is also an important feature and development law in the accumulation of Chinese traditional health culture. Judging from medical archaeology, the development of health preservation concept in the pre-Qin period is of great benefit for people to understand the origin of health preservation and its early development, correctly view health preservation, improve the concept of health preservation, promote the formation of a good lifestyle, and promote the development of public health undertakings.
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Resumen: El artículo analiza el libro "Comuna 13 de Medellín. El Drama del Conflicto Armado" publicado por Yoni Alexander Rendón Rendón, en 2007 cuando el autor era patrullero de la Policía Nacional, en una las zonas más violentas de Colombia: los barrios populares de Medellín. El libro se analizó en sus dimensiones textuales y extratextuales lo que permitió clasificarlo en el género testimonial y en algunos de los universos discursivos sobre el conflicto urbano, lo que explica su inserción exitosa en las disputas sobre la verdad de lo ocurrido en la Comuna 13 en octubre de 2002 en la operación Orión.
Abstract The article analyzes the book "Comuna 13 de Medellín. El Drama del Conflicto Armado" published by Yoni Alexander Rendón Rendón Rendón, in 2007 when the author was a patrolman of the National Police, in one of the most violent areas of Colombia: the popular neighborhoods of Medellín. The book was analyzed in its textual and extratextual dimensions, which allowed it to be classified in the testimonial genre and in some of the discursive universes on the urban conflict, which explains its successful insertion in the disputes about the truth of what happened in Comuna 13 in October 2002 in the Orion Operation.
Subject(s)
Acupuncture , Acupuncture Therapy , Books , Medicine, Chinese Traditional , Qi , SensationABSTRACT
O livro do Trevor Owens expõe uma importante visão sobre a preservação digital contemporânea onde ele discute abordagens teóricas e práticas e apresenta-os com conceitos e conexões inovadores. Este resumo discute 10 dos 16 axiomas que são lançados como o ponto de partido do livro. Estes axiomas são curtos, mas profundos em importância como pensamento base para a elaboração de programas de preservação digital.
Trevor Owens' book exposes important insights into contemporary digital preservation where he discusses theoretical and practical approaches and presents these with innovative concepts and connections. This summary discusses 10 of the 16 axioms that are launched as the starting point of this book. These axioms are short, but deep in importance as the basis for the development of digital preservation programs.
El libro de Trevor Owens expone una visión importante de la preservación digital contemporánea, donde analiza enfoques teóricos y prácticos y les presenta como conceptos y conexiones innovadores. Este resumen analiza 10 de los 16 axiomas que se lanzan como punto de partida del libro. Estos axiomas son cortos, pero de gran importancia como base para el desarrollo de programas de preservación digital.
Subject(s)
Humans , Information Management , Book Review , Books , Information Systems , Comment , Copying Processes , Data Curation , Information ServicesABSTRACT
Resumen El presente artículo profundiza en la forma como los medios de comunicación tienen agencia en la construcción de creencias sociales, narrativas del pasado y orientaciones emocionales colectivas sobre el enemigo que agudizan la polarización política y legitiman las salidas armadas al conflicto social y político que existe en Colombia desde hace más de cinco décadas. En los resultados se evidencia un discurso lineal, hegemónico y homogéneo que está claramente inducido desde los medios de comunicación, según la voz de los participantes, que constituye un enemigo absoluto en las guerrillas, particularmente en las FARC, estigma que se extiende a manifestaciones políticas de izquierda o favorables a una solución política negociada del conflicto armado. De otro lado, un actor referido como poco conocido, confundido con las guerrillas o considerado un mal menor o legitimado, son los paramilitares y una narrativa del héroe que se sacrifica, nos cuida y nos protege, en las Fuerzas Militares, de quienes se minimizan sus acciones violatorias de los derechos humanos. Se concluye sobre la necesidad de poner en discusión el papel de los medios de comunicación masiva y las redes sociales, contrastando críticamente la información que ofrecen.
Abstract This article delves into how mass media have agency in building social beliefs, narratives of the past, and collective emotional orientations about the enemy, which sharpen political polarization and legitimize the armed exits to the social and political conflict, which has existed in Colombia for more than five decades. The results show a linear, hegemonic, and homogeneous discourse, which is induced clearly from the media, according to participants' voice, which constitutes an absolute enemy in guerrillas, particularly in the FARC, a stigma that extends to left-wing political demonstrations or to a pro-political settlement of the armed conflict. On the other hand, an actor referred to as little known, confused with guerrillas or considered a minor or legitimized evil, are the paramilitaries and a narrative of the hero who sacrifices, cares for us, and protects us, in the Military Forces, from those who minimize their violated human rights actions. It concludes on the need to discuss the role of mass media and social media, critically by contrasting the information they offer.
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Analisa-se o agenciamento da memória coletiva e os processos de reconstrução e representação do passado de uma das principais escolas de samba do Rio de Janeiro a Portela por meio de um rito comensal: a feijoada da família portelense. Esta é promovida regularmente por representantes da ala de compositores dessa escola de samba. Examinam-se diversos aspectos que singularizam este evento de comensalidade: seu sistema culinário, seu modo de organização, seus conteúdos afetivos, os processos de identificação e de corporalidade lá produzidos. Os procedimentos de coletas de dados foram: revisão bibliográfica, entrevistas semiestruturadas e etnografia. No que tange aos resultados, infere-se que o processo de construção da identidade portelense é uma marca social de distinção cujos principais esteios são: memória do passado da agremiação, considerado cheio de glórias e vitórias e o compartilhamento de práticas ditas tradicionais como rodas de sambas e feijoadas.
We analyze the agency of collective memory and the processes of reconstruction and representation of the past of one of Rio de Janeiro's main samba schools Portela through a commensal rite: the feijoada of the Portelense family. This rite is regularly promoted by representatives of the composers of the samba school. Several aspects that characterize this event of commensality are examined: its culinary system, its mode of organization, its affective contents, the processes of identification and corporality produced there. The procedures for data collection were: bibliographic review, semi-structured interviews and ethnography. Regarding the results, it is inferred that the process of the identity of being Portelense is a social mark of distinction whose main pillars are: memory of the past of the association, that is considered full of glory and victories, and the sharing of so-called traditional practices such as events with sambas and feijoadas.
Subject(s)
Cooking , Cultural Characteristics , Anthropology, CulturalABSTRACT
Barilius bendelisis (Hamilton) inhabits cold water drainages of the Himalayan region, occurring near the stream banks. It is an important component of the diet of rural population of Uttarakhand and Jammu. Despite the aquaculture importance of B. bendelisis, no extensive molecular characterization from two geographically isolated rivers, Alaknanda and Chenab, has been conducted. In order to study those aspects, 567 samples of B. bendelisis were analysed and collected from these tributaries of two geographically isolated rivers between March of 2015 and April 2017. The morphometric data were analysed by means of truss analysis using tpsDig2 and PAST, whereas the genetic characterization was performed using the COI gene. In truss analysis 14 landmarks resulting in 90 measurements were studied from the digitized images of the sampled specimens. In total 23 measurements exhibited significant differences among the populations of B. bendelisis. The principal component analysis (PCA) generated seven components explaining- 93.15 % of total variance. Discriminant function analysis (DFA) revealed that 83.8 % of the specimens were classified into their original populations. Truss based morphometry and Maximum likelihood type of phylogenetic tree revealed heterogenicity between the two geographically isolated populations of B. bendelisis.
Barilius bendelisis (Hamilton) habita las aguas frías de de las riberas de los ríos del Himalaya. Es un componente importante de la dieta de la población rural de Uttarakhand y Jammu. A pesar de la importancia de B. bendelisis en la acuacultura, no se reportan caracterizaciones moleculares de los ríos geográficamente aislados, Alaknanda y Chenab. Para estudiar estos aspectos, analizamos 567 muestras de B. bendelisis que se recolectaron de los afluentes de estos dos ríos entre marzo 2015 y abril 2017. Analizamos los datos morfométricos por medio del análisis truss utilizando tpsDig2 y PAST y para la caracterización genética utilizamos el gen COI. En el análisis truss 14 puntos de referencia que resultaron en 90 medidas se analizaron de imágenes digitalizadas de especímenes muestreados. Un total de 23 medidas mostraron diferencias significativas entre las poblaciones de B. bendelisis. El análisis de componentes principales (PCA) generó siete componentes explicando el 93.15 % del total de la varianza. El análisis de función discriminante (DFA) reveló que el 83.8 % de los especímenes fue clasificado dentro de sus poblaciones originales. La morfometría basada en el análisis de truss y el árbol filogenético de máxima verosimilitud revelaron hetrogeneidad entre las dos poblaciones geográficamente aisladas de B. bendelisis.
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Background: Gestational Diabetes Mellitus (GDM) accounts for almost 90% of all pregnancies complicated by diabetes. Its prevalence in the Indian population ranges from 5.5% to 11.5 %.Methods: The present study was undertaken to assess the incidence of GDM among antenatal mothers admitted in Goa Medical College for a period of 18 months and also to study the risk factors associated with GDM amongst such cases.Results: Present study revealed that among 7717 antenatal mothers who were admitted and delivered in our Hospital, 424 women were diagnosed with GDM. Of these women diagnosed with GDM, almost one third were in the age group of 31- 35 years (35.8%); 56.2 % of these women were multigravidas. Advancing maternal age, rising parity, obesity, family history of Diabetes Mellitus (DM) and past history of GDM were among the risk factors found to be significantly associated with GDM.Conclusions: The incidence of GDM in present study population was 5.49%. Advancing maternal age, maternal obesity, family history of DM and past history of GDM were found to be important determinants of GDM.
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Unmet healthcare needs are being used as an important indicator of the accessibility of healthcare services worldwide. To examine current status and trends of unmet needs in Korea, we used data from four sources: the Korea National Health and Nutrition Examination Survey (KNHANES, 2007–2017); the Community Health Survey (CHS 2008–2017); the Korea Health Panel Survey (KHP 2011–2015); and the Korean Welfare Panel Study (KOWEPS 2006–2017). The proportion of individual reporting unmet healthcare needs as of 2017 was 8.8% (KNHANES), 10.6% (CHS), and 12.4% (KHP as of 2015). The proportion of households reporting unmet healthcare needs due to cost was 0.5% (KOWEPS). Annual percentage change was −19.2%, −13.3%, −5.8%, and −13.3% respectively. Low income populations had more unmet healthcare needs than high income populations. However, unlike the last two studies, the main reason for unmet medical reasons was that there was no time regardless of income level.
Subject(s)
Delivery of Health Care , Family Characteristics , Health Surveys , Korea , Nutrition Surveys , Population Growth , PovertyABSTRACT
Unmet healthcare needs do not end with the phenomenon itself, but lead to possibilities of increased severity of illness. Missed opportunities for treatment at the right timing increase possibilities of complications, and affect prognosis of disease. To examine current status and trends of unmet needs in Korea, we used data from four sources: the Korea National Health and Nutrition Examination Survey (KNHNES, '2007–2016); the Community Health Survey (CHS '2008–2016); the Korea Health Panel Survey (KHP '2011–2014); and the Korean Welfare Panel Study (KOWEPS '2006–2016). The proportion of individual reporting unmet healthcare needs as of 2016 was 8.8% (KNHNES), 11.5% (CHS), and 12.8% (KHP, as of 2014). Annual percentage change which characterizes trend for the follow-up period was −9.9%, −3.1%, and −1.3%, respectively. The proportion of individuals reporting unmet healthcare needs due to cost was 1.8% (KNHNES), 1.5% (CHS), and 3.0% (KHP). The proportion of households reporting unmet healthcare needs due to cost was 1.0% (KOWEPS). Annual percentage change was −10.0%, −15.2%, −5.4%, and −17.5%, respectively. Low income populations had more unmet healthcare needs than high income populations. Therefore, in order to improve unmet healthcare needs, it is necessary to focus on low income populations.
Subject(s)
Delivery of Health Care , Family Characteristics , Follow-Up Studies , Health Surveys , Korea , Nutrition Surveys , Population Growth , Poverty , PrognosisABSTRACT
This study aims to determine the effects of formaldehyde exposure on self-reported symptoms of respiratory-eye mucosa and integumentary system during anatomy practices among Korean medical students. Data were collected using the web-based survey. Study subjects in 1st and 2nd grade medical student, and having anatomy dissection in medical college and medical graduate school. A total of 463 students from the 14 medical college and medical graduate school participated in this study. The results show that 261 (56.4%) of the participants responded feeling discomfort above moderate at anatomy dissection. After anatomy dissection, 104 (43.2%) students responded aggravating the symptom allergic rhinitis, xerophthalmia and so on. 209 (95.0%) of them responded the new symptom's appearance. In the result of multiple logistic regression, women (OR: 2.000, 95% CI: 1.169~3.421) and the students with feeling discomfort (OR: 3.190, 95% CI: 1.807~5.632) were more likely to increase the risk of pre-existing respiratory · eye mucosal system symptom's aggravation than the counter parts. For pre-existing integumentary system symptom's aggravation, risk is significantly higher in elder age group (OR: 2.612, 95% CI: 1.187~5.750) and with disapproval protective equipments (OR: 2.217, 1.006~4.885). In case of new symptom's appearance, people with feeling discomfort above moderate (OR: 5.097, 95% CI: 1.075~24.160) in respiratory · eye mucosal system were more likely to increase the risk of new symptom's appearance. And for integumentary system, risk was higher in people with feeling discomfort (OR: 1.921, 95% CI: 1.218~3.031), in woman (OR: 1.711, 1.090~2.686) and without enough protective equipments preparation (OR: 1.953, 1.189~3.210). This study confirms the protective equipments for minimizing exposure from chemicals for cytological fixation (e,g formaldehyde) is not worn enough and students in anatomy dissection experience discomfort and disease after anatomy dissection. Therefore, this study indicates that the safe guideline in anatomy dissection should be enhanced and institutional strategy to protect student's right of health should be provided.
Subject(s)
Female , Humans , Formaldehyde , Integumentary System , Logistic Models , Mucous Membrane , Rhinitis, Allergic , Students, Medical , XerophthalmiaABSTRACT
@#BACKGROUND. According to the World Health Organization (WHO), 10-15% of couples of reproductive age have infertility. According to researcher D. Sukhe (1999), hormonal infertility in the reproductive age of women was 33.6%, which was a large part of the cause of infertility. In recent years, the number of cases of endocrine disorders, including malignancy and sexually transmitted infections, have been increasing year by year. According to WHO reports, thyroid disorders have a prevalence of 49.3% among active reproductive age (30-50) group. According to the report of the Health Development Center in 2016, since the thyroid disorders are the second most common disease in endocrine gland disease, our study has found that the infertility in reproductive age of women can be substantial due to the loss of thyroid gland. OBJECTIVE. To study the relationship between the thyroid gland antibodies and female infertility. MATERIAL AND METHODS. The study was carried out in 20-45 year old couples and was modeled as an analytical study model. The questionnaire was used for the couple’s interviews, antroplogical measurements, and serum was analysed. On the serum, anti-TPO and аnti-TG carbohydrates were identified by the Cobas e-411 analyzer under the manufacturer’s accompanying protocol. RESULTS. Prevalence of TAI, in 6.7% positive anti-Tg were found, and 14.3% had positive TPO. In 3.7% of cases, both types of autoantibodies were present. We analysed binary logistic regression for anti-TPO and anti-TG autoantibody in the positive and negative group in relation to the past obstetrics history. A=Accoding to the analysis, evidence of positive anti-TPO and anti-Tg increased the risk of miscarriage by 2.2 times (OR = 2.2, p <0.01). CONCLUSION: Women with infertility in our study have high percentage of subclinical hypothyroidism and have higher rate of thyroid autobodies in serum which could be a problem for women with infertility and pregnancy complications due to the loss of thyroid gland. Thus, there is a need to develop intervention guidelines for recovery and treatment of these types of infertility.
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@#BACKGROUND: According to the World Health Organization (WHO), 10-15% of couples of reproductive age have infertility. According to researcher D. Sukhe (1999), hormonal infertility in the reproductive age of women was 33.6%, which was a large part of the cause of infertility. In recent years, the number of cases of endocrine disorders, including malignancy and sexually transmitted infections, has been increasing year by year. According to WHO reports, thyroid disorders have a prevalence of 49.3% for active reproductive age (30-50). According to the report of the Health Development Center in 2016, since the thyroid disorders are the second most common disease in endocrine gland disease, our study found that the infertility in reproductive age of women can be substantial due to the loss of thyroid gland. METHODS: The study was carried out by the couple of 20-45 year-olds and modeled as an analytical study model. The questionnaire was used for the couple’s interviews and some of the measurement of body and serum use of TOSOH Corporation AIA-360, Tokyo, Japan. On the serum, anti-TPO and аnti-TG carbohydrates are identified by the Cobas e-411 analyzer under the manufacturer’s accompanying protocol. RESULTS: 76.7% of women were diagnosed with infertility euthyroid, 0.7% hyperthyroidism, 22.6% hypothyroidism (3.8% with overt hypothyroidism and 18.8% subclinical hypothyroidism). Prevalence of TAI, in 6.7% isolated positive anti-Tg were found, and 14.3% had isolated positive TPO, In 3.7% of cases, both types of autoantibodies were present. We analysed binary logistic regression for anti-TPO and anti-TG autoantibody in the positive and negative group in past obstetrics history, evidence of positive of anti-TPO and anti-Tg was increased risk of miscarriage 2.2 times (OR = 2.2, p <0.01). CONCLUSIONS: Women with disorders in our study have high percentage of subclinical hypothyroidism and have higher rate of thyroid autobodies in serum which may be a problem for women with infertility and pregnancy complications due to the loss of thyroid gland. There is a need to develop a principle of recovery and treatment.
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Abstract Decisions often imply trade-offs that force people to accept missing an opportunity in the past or in the future. However, it is not fully clear whether a past miss or a future miss elicits more regret. In a direct comparison, previous research had found support for the greater impact of future misses. In an experimental study with 216 participants, we replicated and extended previous research by testing the strength of the future miss in a separate evaluation and with different periods. Results show that, when evaluated separately, future misses caused less regret than past misses. However, future misses made participants change their feelings of regret more intensely than past misses did. Also, regret levels did not decrease when future misses were further away. Our findings support the strength of future misses on regret but also show contrasting effects when evaluated separately.
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Humans , Male , Female , Adult , Decision Making , Emotions , GoalsABSTRACT
<p>The purpose of this study was to assess an impact of water immersion recovery after short distance swimming on the recovery process in pulmonary functions in individuals with the past history of bronchial asthma (PHA). Eleven Japanese healthy males with PHA (23 years) volunteered to perform two bouts of a 25-m maximal front crawl session in an indoor pool. The two bouts were separated by either 10-min of recovery on the land (L-session) or the same condition with water immersion to the neck (W-session), using a counterbalanced crossover design. Water temperature was 30 °C. Forced vital capacity (FVC) and forced expiratory volume in one second (FEV<sub>1.0</sub>) (%predicted) were measured according to the following time course; at baseline (REST), water immersion to the neck (WIN) before the swimming session, after 5-min (REC-5) and 10-min (REC-10) recovery with the assessment of dyspnea sensation (ADS) at the same time point. %FVC and %FEV<sub>1.0</sub> at WIN, REC-5 and REC-10 in the W-session were significantly lower than those REST. A similar reduction was observed at WIN in the L-session, and %FEV<sub>1.0</sub> at REC-5 was significantly different from those REST. The subjects had higher ADS at REC-5 in both sessions compared with those REST. %FVC and %FEV<sub>1.0</sub> at REC-5 and REC-10 in W-session were significantly lower than those at REC-5 and REC-10 in L-session. These results indicates a negative impact of not only water immersion recovery but also recovery on the land after short distance swimming on pulmonary function in individuals with PHA.</p>
ABSTRACT
Objective:To explore the correlation with neonatal congenital cytomegalovirus infection,maternal primary infection and secondary infection.Methods: 48 neonates with congenital CMV infection were assigned to infection group with their mothers.And the other 30 couples without congenital CMV infection were assigned to negative group with their mothers.The level of CMV-IgM/IgG and affinity of CMV-IgG in peripheral blood were tested by CLIA,and CMV-DNA in mother′s milk,peripheral blood and urine of the newborn was tested by fluorescent quantitation PCR.We also analyzed the differences of the test results between the two groups and performed a retrospective analysis to compare the levels of CMV-IgG of the mother with early pregnancy with the result of this test.Results: In the infection group,the level of CMV-IgG in peripheral blood and CMV-DNA in milk was significantly higher than those in the negative group,the difference was statistically significant(P0.05).Conclusion: It is a high-risk factor for neonatal congenital cytomegalovirus infection that CMV-IgG level of the pregnant women is promted by the reactivation or reinfection of cytomegalovirus.It is important to monitor CMV-IgM/IgG during pregnancy.