Advances in magnetic resonance technique for tumor imaging

The development of advanced magnetic resonance (MR) imaging techniques for tumors has not only lead to improved diagnostic accuracy, but has also assisted with tumor staging, surgical planning, and postoperative follow-up study. Recently introduced and/or clinically used MR imaging techniques for tumors, including chemical exchange saturation transfer imaging, molecular imaging, magnetic resonance spectroscopy, perfusion, and blood flow suppression techniques, could improve diagnostic accuracy and provide useful information to guide the management of tumors. It is essential to properly obtain and evaluate advanced MR images for tumors, depending on the specific characteristics of each tumor.

Distinguish brain glioma recurrence for postoperative radiotherapy patients using perfusion weighted magnetic resonance imaging / 中华放射肿瘤学杂志

ObjectiveTo evaluate the role of perfusion weighted magnetic resonance imaging ( PWMRI ) in distinguishing brain glioma recurrence for postoperative radiotherapy patients.Methods Thirty-five patients with suggested recurrent brain glioma (20 true,15 false) were examined by conventional MRI and PWMRI.Regions of interests (ROI) were manually drawn in contrast-enhancing lesion,surround edema region and normal white matter of contra-lateral brain on regional cerebral blood volume (rCBV) images.rCBV values of ROI and rCBVmax were measured,the standardized rCBV ratios were calculated,The mean rCBVmax ratio were compared between two lesion types with group t-test.The rCBVmax ratios of contrastenhancing regions was analyzed by the receiver operating characteristic curve.ResultsThe mean rCBVmax ratio of contrast-enhancing lesion in tumor recurrence was higher than those in non tumor recurrence (4.36vs 1.28,t =3.00,P =0.005 ).The mean rCBVmax of edema regions in tumor recurrence was also higher than those in non tumor recurrence ( 1.79 vs 0.85,t =2.41,P =0.026).Four patients with recurrent tumor and three with non tumor recurrence were wrong diagnosed when set the recurrent tumor rCBVmax ratio ＞2.15.The diagnostic sensitivity,specificity and accuracy for recurrent tumor by PWMRI were 80％respectively.Conclusion PWMRI examination is a useful method for distinguishing brain glioma recurrence.