ABSTRACT
Peribiliary region is the anatomical space adjoining the intra and extrahepatic biliary system and comprises of portal vein, hepatic artery, nerves and lymphatics. This region is prone to several pathologies ranging from congenital, infective, inflammatory, traumatic and neoplastic. Due to the wide spectrum of abnormalities, it is often difficult to reach a final diagnosis. This review focusses to draw a roadmap to help reach a diagnosis of abnormalities encountered in this region by highlighting the characteristic imaging features associated with these abnormalities.
ABSTRACT
São descritos os achados macroscópicos e histopatológicos de cistos peribiliares em uma fêmea adulta de leão-africano (Panthera leo). Macroscopicamente, todos os lobos hepáticos continham numerosos cistos preenchidos por líquido translúcido. Histologicamente, os cistos estavam localizados no hilo hepático e nos tratos portais. Os cistos eram revestidos internamente por epitélio simples, constituído por células colunares ou cuboidais e não mucinosas, de acordo com avaliação para ácido periódico de Schiff/azul alciano. Na imuno-histiquímica, todas as células desse epitélio foram positivas para citoceratina. O leão morreu de complicações relacionadas a um carcinoma pulmonar e não foram observadas alterações clínicas associadas à lesão hepática, comprovando que cistos peribiliares em leões também ocorrem não associados a sinais clínicos.
The gross and histopathological aspects of peribiliary cysts in an adult African lioness (Panthera leo) are described. Grossly, all hepatic lobes contained numerous cysts filled with translucent fluid. Histologically it was observed that the cysts were located in the hepatic hilum and in the portal triads. Periodic acid-Schiff and Alcian blue stains, revealed the cysts to be lined by simple, non-mucinous, cuboidal or columnar epithelium. In immunohistochemistry staining all cells comprising this epithelium were positive for cytokeratin. The lioness died due to complications stemming from a pulmonary carcinoma and no clinical signs related to the hepatic lesion were observed, demonstrating that also in lions the peribiliary cysts occur as non-clinical disease associated lesions.
Subject(s)
Animals , Gastroenterology , Lions , Autopsy/veterinary , Bile Ducts, IntrahepaticABSTRACT
Hepatic peribiliary cysts are characterized by multiple tiny cysts of peribiliary glands located in the hilum of the large portal tracts. A 54-year-old man was diagnosed as multiple peribiliary cysts by a magnetic resonance cholangiopancreatogram. A course of observation was taken, since surgery due to misdiagnosis of peribiliary cysts as a malignancy is a possibility. The present case highlights the need for precise diagnosis and observation of peribiliary cysts.