Fetomaternal outcome in women with hemolysis, elevated liver enzymes and low platelet count syndrome: a retrospective study

Background: HELLP (hemolysis, elevated liver enzymes and low platelet count) syndrome which is a variant form of severe preeclampsia is an important cause of maternal and fetal mortality and morbidity. The importance lies in the early diagnosis and timely intervention for better fetal and maternal outcome. The objective of this study was to assess the maternal and fetal outcome in pregnancies complicated with HELLP syndrome.Methods: This is a retrospective study analyzing fetomaternal outcome in 63 women diagnosed with HELLP syndrome in the department of obstetrics and gynecology, Government Medical College, Thrissur from 1st January 2014 to 31st December 2016. Details were collected from data records library.Results: Among 7,566 deliveries, 63 women (0.83%) had HELLP syndrome. Mean age was 29.5 years. 47.6% (n=30) women developed HELLP syndrome at gestational age less than 34 weeks. Maternal complications were abruption (27.78%), acute kidney injury (16.67%), DIC (16.67%), sepsis (11.11%) and postpartum hemorrhage (11.11%). In this study, HELLP syndrome lead to one maternal death (1.58%). The perinatal mortality was 25.75%.Conclusions: HELLP syndrome is an alarming complication, which brings high maternal and perinatal morbidity and mortality.

If you get pregnant in the 90s what are the chances that you will have a normal pregnancy and a normal baby?

What are the chances of a pregnant woman having a normal pregnancy and a normal baby in the 90s. This is an assessment after regionalization of perinatal care was established in Quezon City in 1986 through the setting up of a Q.C. Perinatal Council. The Council is composed of the Perinatal Center, Philippine Childrens Medical Center, Quezon City General Hospital, Veterans Memorial Medical Center and Quirino Memorial Medical Center. One thousand consecutive, unselected pregnancies were followed up from the first trimester until delivery. Eight hundred sixty eight (86.8%) had a normal pregnancy and baby; one hundred seven (10.7%) had premature deliveries. There were 4 stillbirths, 9 neonatal deaths and 18 NICU admissions. The perinatal mortality rate was 13 per 1000 pregnancies. There were 32 who developed hypertensive complications of pregnancy. Chance of developing a normal pregnancy is 6 out of 10, an abnormal pregnancy is 2 out of 10 and ending in an abortion is 2 per 100.