ABSTRACT
RESUMEN: El ácido hialurónico ha sido empleado en diferentes áreas anatómicas, su aplicación para el rejuvenecimiento facial y en las lesiones de la articulación son conocidos; sin embargo, la aplicación en defectos periodontales y perimplantares tiene limitada información. El objetivo de esta investigación es mostrar los resultados clínicos de una serie de casos de sujetos con defectos periodontales menores tratados con la aplicación de ácido hialurónico. Se incluyeron 4 sujetos que presentaron espacios negros y recesiones gingivales en los que se aplicó el protocolo de instalación de ácido hialurónico al 0,2 % en diferentes momentos; el seguimiento clínico demostró eficiencia en la recuperación estética y estabilidad en los aumentos. Es posible concluir que esta técnica mínimamente invasiva es promisoria para tratar defectos periodontales y perimplantares menores.
ABSTRACT: Hyaluronic acid has been used in different anatomical areas, where its application and use for facial rejuvenation as well as joint injuries are known. However, information of its application in periodontal and peri implant defects is limited. The aim of this research is to show the clinical results of a case series in subjects with minor periodontal defects treated with the application of hyaluronic acid. Four subjects with black spaces and gingival recessions were included; the protocol for application of 0.2% hyaluronic acid was realized at different times; the clinical follow-up showed efficiency in the aesthetic recovery and stability in the increases. It is possible to conclude that this minimally invasive technique is promising to treat minor periodontal and peri implant defects.
Subject(s)
Humans , Male , Female , Middle Aged , Young Adult , Gingivitis , Anti-Infective Agents, Local , Periodontal Diseases , Dental Implantation, Endosseous , Esthetics, Dental , Peri-Implantitis , Hyaluronic Acid/therapeutic useABSTRACT
La hidroxiapatita (HA) es un componente mineral del hueso. Se ha comercializado la HA sintética o aloplástica en forma porosa o no porosa, densa y reabsorbible o no reabsorbible. Se utiliza como injerto óseo dada sus propiedades osteoconductivas y estimuladoras de proliferación celular generando así condiciones favorables para la regeneración tisular. El objetivo de éste trabajo es evaluar la efectividad del tratamiento con HA en cirugías de implantes dentales e injertos óseos. Se realizó una revisión sistemática. Se revisó ensayos clínicos sobre cicatrización y los injertos de HA sintética en Pubmed, Cochrane Library, Google Académico, Blackwell y Ebsco. Los criterios de selección son pacientes candidatos a tratamientos de defectos periodontales o rehabilitación con implantes dentales, sin alteraciones sistémicas de importancia. La estrategia se resume en los siguientes puntos: Identificación del problema, Identificación de términos de búsqueda, Búsqueda sistemática, Selección de artículos mediante utilización de guías de análisis crítico, Incorporación de la información al REVMAN®, Análisis de sesgos y Meta análisis. Al evaluar el metaanálisis se observa que la HA es efectiva para la cicatrización de injerto óseo. Cuando se omiten los estudios de bajo peso, la medida de resumen se mantiene en la HA. El tratamiento con HA en la cicatrización ósea y de implantes dentales resulta positivo y con una alta tasa de éxito en el largo plazo aunque su rango de efectividad varía con los materiales a los cuales ésta se asocie.
Hydroxyapatite (HA) is a mineral component of bone. Hydroxyapatite has been marketed as synthetic or alloplastic, porous or nonporous, dense and resorbable or non-resorbable form. It is used as bone graft due to its osteoconductive properties and stimulation of cell proliferation, generating favorable conditions for tissue regeneration. The aim of this study is to evaluate the effectiveness of treatment with HA in dental implant surgeries and bone grafts. We conducted a systematic review. Clinical trials on healing and graft of synthetic hydroxyapatite were reviewed in PubMed, Cochrane Library, Google Scholar, Blackwell and Ebsco. The selection criteria was: patient candidates for treatment of periodontal defects or rehabilitation with dental implants without significant systemic abnormalities. The strategy is summarized in the following: Identification of the problem, identifying search terms, systematic search and selection of articles by using critical analysis guides, Incorporating REVMAN ® information, unbiased analysis, and Meta-analysis. Assessing the meta-analysis shows that the HA is effective for healing bone graft. When omitting low weight studies, the summary measure remains in the HA. Treatment with HA in bone healing and dental implants, is positive with a high rate of success in the long term, although its effective range varies according to the materials to which it is associated.
Subject(s)
Humans , Dental Implantation/methods , Durapatite/administration & dosage , Sinus Floor Augmentation/methods , Wound Healing/drug effects , Bone Transplantation/methodsABSTRACT
Background: The present clinical trial was designed to evaluate the effects of bioactive glass in treatment of periodontal intra-bony defects. Methods: 25 patients 23-55 years of age with intra-bony defects completed 1 year study. After completion of initial therapy, defects were randomly assigned to either a test or control procedure. Following flap reflection root planning and removal of chronic inflammatory tissue in both groups test defects were restored with bioactive glass, while open flap debridement was done in control sites. Muco-periosteal flaps were replaced sutured and periodontal dressing was used. Follow up was carried out weekly, 3 months 9 months and 1 year post surgery. Plaque score, sulcus bleeding score probing pocket depth were recorded at baseline, 3 months and 1 year. Standardized radiographs using RVG was taken at baseline, immediately post operatively and at 1 year. Results: Radiographs showed a significant increase in radiographic density and volume between defects treated with bioglass when compared with open flap debridement alone. Probing pocket depth, probing attachment level showed improvement in test and control site with greater trend to improvement in test site. Conclusion: It was concluded that bioglass is effective as an adjunct to conventional surgery in treatment of intra-bony defects.
ABSTRACT
La hidroxiapatita (HA) es un componente mineral del hueso. Se ha comercializado la HA sintética o aloplástica en forma porosa o no porosa, densa y reabsorbible o no reabsorbible. Se utiliza como injerto óseo dada sus propiedades osteoconductivas y estimuladoras de proliferación celular generando así condiciones favorables para la regeneración tisular. El objetivo fue evaluar la efectividad del tratamiento con HA en cirugías de implantes dentales e injertos óseos. Se realizó una revisión sistemática. Se revisó ensayos clínicos sobre cicatrización y los injertos de HA sintética en Pubmed, Cochrane Library, Google Académico, Blackwell y Ebsco. Los criterios de selección son pacientes candidatos a tratamientos de defectos periodontales o rehabilitación con implantes dentales, sin alteraciones sistémicas de importancia. La estrategia se resume en los siguientes puntos: Identificación del problema, Identificación de términos de búsqueda, Búsqueda sistemática, Selección de artículos mediante utilización de guías de análisis crítico, Incorporación de la información al REVMAN®, Análisis de sesgos y Metaanálisis. Al evaluar el metaanálisis se observa que la HA es efectiva para la cicatrización de injerto óseo. Cuando se omiten los estudios de bajo peso, la medida de resumen se mantiene en la HA. El tratamiento con HA en la cicatrización ósea y de implantes dentales resulta positivo y con una alta tasa de éxito en el largo plazo aunque su rango de efectividad varía con los materiales a los cuales ésta se asocie.
Hydroxyapatite (HA) is a mineral component of bone. The hydroxyapatite has been marketed: synthetic or alloplastic, as porous or nonporous, dense and resorbable or non-resorbable. These are used as bone graft due to their osteoconductive properties and stimulation of cell proliferation that generate favorable conditions for tissue regeneration. The objective of this study was to evaluate the effectiveness of treatment with HA in dental implant surgeries and bone grafts. We conducted a systematic review and studied clinical trials on healing and graft of synthetic hydroxyapatite in PubMed, Cochrane Library, Google Scholar, Blackwell and Ebsco. Selection criteria were: patient's candidate to treatment of periodontal defects or rehabilitation with dental implants without significant systemic abnormalities. The strategy is summarized in the following: Identification of the problem, identifying search terms, systematic search and selection of articles by using critical analysis guides, incorporating REVMAN® information, unbiased analysis, and Meta-analysis. Our results indicate that assessing the meta-analysis shows that the HA is effective for healing bone graft. When omitting low weight studies, the summary measure remains in the HA. In conclusion, treatment with HA in bone healing and dental implants is positive with a high success rate in the long term, although its effective range varies with the materials to which it is associated.
ABSTRACT
The purpose of this study is to evaluate the regenerative potential of calcium sulfate in the treatment of 2-wall intrabony defects as compared to the flap procedure alone. Periodontal healing of surgically created 2-wall intrabony defects grafted with calcium sulfate were evaluated in dogs. Experimental 2-wall intrabony defects of 4x4x4mm were surgically created in the upper anterior edentulous areas between the canines. The test sites include four 2-wall intrabony defects in 4 dogs treated with a calcium sulfate graft. Another four 2-wall intrabony defects in 4 dogs were treated with flap surgery alone as the control sites. Healing was evaluated after 8 weeks. Apical extention of junctional epithelium(JE) was 2.29mm in the control group and 0.50mm in the test group. The length of connective tissue adhesion(CTA) was 0.53mm in the control group and 1.16mm in the test group. The length of new cementum(NC) was 1.17mm for the control group and 2.55mm for the test group. The length of new bone(NB) was 1.02mm in the control group and 2.27mm for the test group. The test group showed statistically significant differences from the control group in junctional epithelium extension, new cementum and new bone formations (p<0.05). Within the limitations of the present study, the results suggest that calcium sulfate may be a safe and cost-effective bone graft material for the treatment of intrabony periodontal defects.