Giant fibroadenoma or juvenile fibroadenoma of breast: Conservative surgery.

A 10 years prepubertal age girl presented with huge 17 X 14 cm painless breast lump of four months duration. Based on the cytological, imaging and clinical findings a preliminary diagnosis of benign proliferative breast lesion closest to giant fibroadenoma was offered. Giant fibroadenomas are rare in young girls and are difficult to differentiate from low grade phylloides tumor by cytology/ imaging. Giant fibroadenomas have to be differentiated from phylloides tumor by the lack of leaf-like structures and stromal cell atypia and from the breast hamartoma and asymmetric breast hypertrophy in girls by the lack of mammary lobules. Giant fibroadenoma should take its due place in the diagnostic algorithm of the breast tumors. Marginal excision with nipple areola sparing and close follow up should be the standard of treatment in young girls.

Malignant phylloides tumour with giant cells & rhabdomyosarcomatous differentiation: A case report.

Phylloides tumours are uncommon biphasic lesions of breast that are further classified as benign, borderline & malignant. Malignant phylloides tumours must be distinguished from spindle cell carcinoma and primary breast sarcoma. Demonstration of benign epithelial component will help to establish the diagnosis of malignant phylloides, but this may require extensive sampling is some cases. The present case was diagnosed after extensive sampling.