Preliminary phytochemical and physicochemical evaluation of Carallia brachiata (Lour.) Merr. leaves.

In the present study, the preliminary phytochemical and physicochemical studies including fluorescence and thin layer chromatographic analyses of the leaves of Carallia brachiata (Lour.) Merr. (Rhizophoraceae), an Indian medicinal plant used traditionally in the treatment of a variety of human disorders, were carried out with an objective to standardize the plant/plant part (leaves) to be used either as crude drug or in the form of herbal medicine, considering the quality and safety requirements of herbal drugs as per pharmacopoeial standards and/or WHO guidelines.

Evaluation of directly observed treatment short courses at a secondary health institution in Ibadan, Oyo State, Southwestern Nigeria

OBJECTIVE@#To evaluate the success rate of tuberculosis intervention programme at a specialist hospital in Ibadan, Nigeria through a retrospective study as well as carry out physicochemical evaluation of anti-tuberculous agents as a way of eliminating drug-related failure.@*METHODS@#The retrospective study involved the use of quarterly tuberculosis central register at the Government Chest Hospital, Ibadan between 1st quarter (2003) to 4th quarter (2009). Relevant data were extracted from these register with the aid of data collection forms. The basic physicochemical analyses of the drugs given to the patients were also carried out using the International Pharmacopoeia methods.@*RESULTS@#All the drugs examined for their physicochemical properties passed the International Pharmacopeia recommended tests. A total number of 1 260 patients enrolled at the hospital were assessed through case notes. This comprises of 59.4% males of which 69.23% new cases were also males. There was a significant (P0.05). Failure rates in all categories were higher in males than females (P>0.05).@*CONCLUSIONS@#More enlightenment and counseling is still required to meet up with the target for TB control.

Antibacterial activity and physicochemical evaluation of roots of Butea monosperma

Objective: To evaluate the antibacterial activity of the petroleum ether extract of root of Buteamonosperma B. monosperma was studied against Staphylococcus faecalis (S. faecalis), Sterptococcus faecalis (S. faecalis), Aeromonas hydrophilia (A. hydrophilia), Salmonela typhae (S. typhae), Stphylococcus cohni (S. cohni), Escherichia coli (E. coli) and Serratia ficaria (S. ficaria) by using well diffusion method. Results: Petroleum ether extract of root of B. monosperma exhibited a prominent inhibitory effect against bacterial strains. Conclusion: From the result it can be concluded that the B. monosperma extract has potent in vitro antibacterial activity. (B. monosperma). Method: In vitro antibacterial activity of petroleum ether i.e.