ABSTRACT
Objective To observe the effect of Pingchuanning on the levels of LTB4 and sICAM-1 of guinea pigs with asthma. Methods The model guinea pigs of asthma were sensitized with ovalbumin (OVA),the changes of the delitescence of asthma was observed. The levels of LTB4 in serum and sICAM-1 in bronchoalveolar lavage fluid (BALF) were also observed by means of enzyme-linked immunosorbent (ELISA). Result Comparing with the model group,the delitescence of asthma was obviously prolonged in guinea pigs treated by Pingchuanning. The levels of LTB4 and sICAM-1 of guinea pigs with asthma treated by Pingchuanning were significantly lowered (P
ABSTRACT
Objective: To investigate the molecular mechanism of Pingchuanning in treating asthma.Methods: Using reverse transcription-polymerase chain reaction(RT-PCR),cavies' lung tissue Eotaxin mRNA expression were given semi-quantitative analysis.Results: The Eotaxin mRNA levels in asthma model group were increased than the control group,P