ABSTRACT
Pityriasis rotunda (PR) is a rare disease characterized by persistent, sharply defined, oval, scaly patches of dry skin, localized mainly on the trunk and extremities. Its etiology remains unknown. However, several reports suggest that it is a form of acquired ichthyosis vulgaris or a skin manifestation of systemic disease, such as malnutrition, chronic illness, hepatic disease, and malignancies. Although a variety of treatment modalities, including topical lactic acid, urea, tars, emollients, and corticosteroid, have been applied to it, their efficacies are not satisfactory. Herein, we report a case of PR in a healthy man who was successfully treated with oral and topical retinoids.
Subject(s)
Chronic Disease , Emollients , Extremities , Ichthyosis , Ichthyosis Vulgaris , Lactic Acid , Malnutrition , Pityriasis , Rare Diseases , Retinoids , Skin , Skin Manifestations , Tars , UreaABSTRACT
Pityriasis rotunda is an uncommon dermatosis characterized by asymptomatic, multiple, widely distributed, round or oval-shaped, hyperpigmented or hypopigmented, fine, scaly patches. They typically involve the abdomen, the trunk and extremities. Histopathologic findings are consistent with ichthyosis vulgaris, such as hyperkeratosis, hypogranulosis or agranulosis, hyperpigmentation of the basal layer in epidermis, and perivascular lymphohistiocytic infiltration in the dermis. Although the etiology of the disease remains unknown, it has been associated with a variety of underlying systemic diseases including infectious diseases, hormonal disorders, malignancies, and chronic disorders. One clinical case has been reported about the occurrence of the disease during pregnancy of a 24-year-old african woman, but there is only one reported case of exacerbation of the disease during pregnancy in Korea. Herein, we report a case of pityriasis rotunda occurring during pregnancy.
Subject(s)
Female , Humans , Pregnancy , Young Adult , Abdomen , Communicable Diseases , Dermis , Epidermis , Extremities , Hyperpigmentation , Ichthyosis Vulgaris , Korea , Pityriasis , Skin DiseasesABSTRACT
Pityriasis rotunda (PR) is a rare disease characterized by persistent, sharply defined, oval, scaly patches of dry skin, localized mainly on the trunk and extremities. Its etiology remains unknown. However, several reports suggest that it is a form of acquired ichthyosis vulgaris or a skin manifestation of systemic disease, such as malnutrition, chronic illness, hepatic disease, and malignancies. Although a variety of treatment modalities, including topical lactic acid, urea, tars, emollients, and corticosteroid, have been applied to it, their efficacies are not satisfactory. Herein, we report a case of PR in a healthy man who was successfully treated with oral and topical retinoids.
Subject(s)
Chronic Disease , Emollients , Extremities , Ichthyosis , Ichthyosis Vulgaris , Lactic Acid , Malnutrition , Pityriasis , Rare Diseases , Retinoids , Skin , Skin Manifestations , Tars , UreaABSTRACT
Pityriasis rotunda is a rare disease characterized by round to oval, sharply defined, hypopigmented or hyperpigmented, scaly patches of variable number and size located trunk and extremity. The etiology is unknown but it has been associated with a variety of systemic illnesses, such as tuberculosis, malnutrition and malignancy. The first case was a 28-year-old male who presented with a 2-year history of multiple round shaped hyperpigmented patches on the trunk. The second-case was a 38-year-old female who presented with a 2-month history of circular, sharply defined multiple patches with ichthyosiform scaling on the trunk. Both patients had no systemic disease or familial history. We experienced 2 cases of pityriasis rotunda on the trunk without underlying systemic illnesses or familial association.
Subject(s)
Adult , Female , Humans , Male , Extremities , Ichthyosis , Malnutrition , Pityriasis , Rare Diseases , TuberculosisABSTRACT
Pityriasis rotunda is characterized by asymptomatic, multiple, brownish, round or oval shaped, isolated or confluent, fine scaly patches. It has been associated with a variety of underlying systemic diseases. We report a case of pityriasis rotunda occurring in a 15-year-old female patient with nephrotic syndrome and pulmonary tuberculosis.
Subject(s)
Adolescent , Female , Humans , Nephrotic Syndrome , PityriasisABSTRACT
Pityriasis rotunda is an unusual disease characterized by perfectly circular or oval-shaped dyschromic patches with a scaling surface. Histologically, the lesions resemble those of ichthyosis vulgaris. They typically involve the abdomen, the trunk and extremities. The etiology of the disease remains unknown. Pityriasis rotunda has been most commonly associated with tuberculosis, nonlymphoproliferative neoplasms such as hepatocellular carcinoma and gastric carcinoma, and malnutrition. Rarely, hepatic cirrhosis, leprosy, endometriosis, and familial G6PD deficiency can be associated with pityriasis rotunda. We describe here a patient with pityriasis rotunda associated with hepatocellular carcinoma. Pityriasis rotunda can be a presenting sign of hepatocellular carcinoma in the setting of chronic liver cirrhosis.
Subject(s)
Female , Humans , Abdomen , Carcinoma, Hepatocellular , Endometriosis , Extremities , Glucosephosphate Dehydrogenase Deficiency , Ichthyosis Vulgaris , Leprosy , Liver Cirrhosis , Malnutrition , Pityriasis , TuberculosisABSTRACT
Pityriasis rotunda is an uncommon dermatosis characterized by asymptomatic, multiple, widely distributed, strikingly circular hypopigmented or hyperpigmented, scaly patches on the trunk and extremities. Histopathologic findings are consistent with ichthyosis vulgaris. It has been associated with a variety of underlying systemic diseases. We report a case of pityriasis rotunda aggravated during pregnancy.
Subject(s)
Pregnancy , Extremities , Ichthyosis Vulgaris , Pityriasis , Skin DiseasesABSTRACT
Pityriasis rotunda is an uncommon cutaneous disorder characterized by multiple asymptomatic strikingly circular hyperpigmented or hypopigmented, scaly patches on the trunk and extremities with the similar histologic appearance of ichthyosis vulgaris. The majority of cases have been reported in Japan, South Africa and West India, usually in association with an underlying systemic disease, but there are some familial cases without systemic diseases. We report a case of pityriasis rotunda with liver cirrhosis.
Subject(s)
Extremities , Ichthyosis Vulgaris , India , Japan , Liver Cirrhosis , Liver , Pityriasis , South AfricaABSTRACT
Pityriasis rotunda is an uncommon chronic dermatosis characterized by multiple, round or oval, hyperpigmented or hypopigmented patches that have a fine scale on the trunk and extremities. Most of the cases reported predominantly occurred in Oriental and black patients in association with internal disease. However, in Caucasians it has been documented in healthy persons usually as a familial tendency. We report a case of pityriasis rotunda which showed familial occurrence and had no underlying disease.
Subject(s)
Humans , Extremities , Pityriasis , Skin DiseasesABSTRACT
Pityriasis rotunda is an uncommon dermatosis chacracterized by multiple, widely distributed, strikingly circular hypopigmented or hyperpigmented patches that are slightly scaly. Pityriasis rotunda has been associated with certain infective or malignant systemic diseases. No specific and effective treatment is available. A 27-year-old woman afflicted with multiple lesions of pityriasis rotunda on her back, buttock, abdomen and thighs without any local symptoms was treated with topical 20% urea and 0.025% tretinoin twice a day for 1 month. Complete remission with exellent cosmetic result was observed 30 days after this treatment. No recurrence was observed after 2 months later following commencement of treatment. Topical urea and tretinoin can thus be recommended as a practicable approach to the treatment of pityriasis rotunda.
Subject(s)
Adult , Female , Humans , Abdomen , Buttocks , Pityriasis , Recurrence , Skin Diseases , Thigh , Tretinoin , UreaABSTRACT
Pityriasis rotunda (PR) is an uncommon dermatosis characterized by perfectly round, scaly patches. Thus, it has been considered by some to be a dermatophyte infection. PR has also been associated with a variety of underlying systemic diseases. A case is reported, herein, of PR associated with Paget's disease of the bone. Potassium hydroxide (KOH) examination of scale from the lesions was negative. Histologically there was orthokeratotic hyperkeratosis, a normal granular layer, and a mild lymphohistiocytic perivascular infiltrate in the superficial dermis. Sections stained with methenamme silver were negative for fungus. These findings support the theory that PR is not a dermatophyte infection, but a variant of acquired ichthyosis. Treatment with an alpha hydroxy acid lotion is discussed.
Subject(s)
Arthrodermataceae , Dermis , Fungi , Ichthyosis , Pityriasis , Potassium , Silver , Skin DiseasesABSTRACT
We report a case of pityriasis rotunda occurring in a patient with pancreatic adenocarcinoma. The patient was a 64-year old female who had a pancreatic adenocarcinoma. The skin lesions were asymptomatic, multiple, various sized (1 to 15cm in diameter), isolated or confluent and finely scaly light brownish to grayish colored patches on the lower abdomen, back and thigh. Histopathologic findings shawed mild hyperkeratosis, atrophy, loss of granular layer, increased melanin pigments in basal layer of the epidermis and mild perivascular monocytic infiltration in the upper dermis.
Subject(s)
Female , Humans , Middle Aged , Abdomen , Adenocarcinoma , Atrophy , Dermis , Epidermis , Melanins , Pancreas , Pityriasis , Skin , ThighABSTRACT
Fifty six year old woman with liver cirrhosis and 31 year old man in good health had similar skin lesions which were well-defined, round to oval, isolated or confluent, scaly brown patches on her lower back, and his trunk and thighs, respectively, without any symptom. The biopsy specimens taken from the lesions showed slight hyperkeratosis with occasional follicular pluggings, presence of a granular layer, and epidermal flattening in case 1; increased melanin pigment in the basal layer in case 2. In both cases, the upper dermis revealed minirnal perivascular lymphohistiocytic inf iltration. We, therefore, present two cases of pityriasis rotunda and review the literature.