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1.
Rev. chil. nutr ; 50(5)oct. 2023.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1530015

ABSTRACT

Los alimentos expendidos en la vía pública constituyen una fuente de ingreso para familias en países en vías de desarrollo, sin embargo, pueden ser fuentes potenciales de enfermedades transmitidas por alimentos. En Riobamba-Ecuador entre los alimentos de mayor consumo en la vía pública está el plato típico "ceviche de chochos (Lupinus mutabilis)", nutritivo, sensorialmente agradable y con precio accesible. Este estudio evaluó la calidad microbiológica y condiciones sanitarias de 10 puestos de venta. Se realizó el análisis microbiológico a 100 muestras correspondientes a: ceviche e ingredientes por separado (jugo de tomate, chochos desamargados, piel cocida de cerdo y cebollas). Estas muestras se tomaron en dos días diferentes y se cuantificó aerobios mesófilos, enterobacterias y Staphyloccocus aureus. Las condiciones sanitarias de los puestos de venta fueron evaluadas mediante una lista de verificación que incluyó los siguientes parámetros: diseño, ubicación, manipulador, preparación, transporte, comercialización y saneamiento. Los resultados revelan que todas las muestras estaban contaminadas con enterobacterias y S. aureus, 80% presentaban aerobios mesófilos > 6 log10 UFC/g, siendo el ingrediente chocho desamargado, el que aportó mayor carga microbiana en 6 de los 10 puestos de venta. Los resultados de la lista de verificación muestran que las principales deficiencias son: la no utilización de agua potable circulante y la manipulación de manera conjunta de los alimentos y el dinero. En conclusión, existe gran fluctuación del cumplimiento de cada parámetro dentro de las Prácticas Correctas de Higiene por puesto de venta, creando focos o entradas de contaminantes, que se evidencia en los altos recuentos de microorganismos indicadores de calidad sanitaria en el producto final.


Street food constitutes a source of income for several families in the world, mainly in developing countries and emerging economies; however, it can be a potential source of foodborne diseases. In Riobamba-Ecuador, among the most consumed food streets is the typical dish "ceviche de chochos (Lupinus mutabilis) ", a nutritious and pleasant sensory dish at an affordable price. In this study, the microbiological load and sanitary conditions of 10 lupine ceviche stalls were evaluated. Samples of ceviche and its ingredients (tomato juice, debited lupins, pork skin, and onions). These samples (n= 100) were taken on two different days and analysed to quantify mesophilic aerobes, enterobacteria, and S. aureus. The sanitary conditions of the stalls were analysed using a check list consisting of sections focused on design, location, handler, preparation, transportation, marketing and sanitation. The results show that 100% of the samples were contaminated with enterobacteria and S. aureus, 80% of these had mesophilic aerobics > 6 log CFU / g, and the debittered lupin ingredient is the one that provides the highest microbial load in 6 of the 10 stalls evaluated. The results of the check list showed that the main deficiencies are the non-use of circulating drinking water and the joint manipulation of food and money. In conclusion, there is a great fluctuation in the compliance of the Good Hygiene Practises parameters in each street food stall. It causes multiple foci or entrances of contaminants, which is evidenced in the high counts of microorganisms that are indicators of sanitary quality in the final product.

2.
Textos contextos (Porto Alegre) ; 22(1): 44653, 2023.
Article in Portuguese | LILACS | ID: biblio-1526260

ABSTRACT

O objetivo deste artigo é o de chamar atenção para uma série de questionamentos que podem e, a nosso ver, ainda devem ser feitos, acerca de uma suposta, exclusiva e definitiva doutrina política de Platão. Para tanto, inicialmente, é levantada a seguinte pergunta: A República, um dos mais célebres e comentados diálogos escritos por Platão, seria, de fato, o único momento de "sua" obra em que este autor expressaria a "sua" teoria política (comunista)? Amparados na leitura e interpretação imanentista de Hector Benoit a respeito dos diálogos platônicos, partimos da hipótese de que Platão, não sendo Sócrates, expôs ­ através de um personagem denominado Ateniense ­ em seu último diálogo na temporalidade da léxis, As Leis, um projeto de cidade radicalmente distinto daquele d'A República. Tal projeto se baseia na unidade dos contraditórios para a formação educacional dos habitantes de uma cidade composta por amigos que tivessem todas as coisas realmente em comum; cidade que deveria ser realizada na prática, e não apenas na metafísica alma do filósofo, como Sócrates haveria proposto idealisticamente n'A República. Assim, longe de ter abandonado os seus posicionamentos comunistas da juventude, como defendem alguns intérpretes, Platão, ao final da vida, teria, na realidade, os encontrado de modo mais rigorosamente determinado. No final do artigo, Marx e Lênin assumem o protagonismo, o que sugere ser a teoria política um dos fios condutores da milenar tradição dialética


This article aims at drawing attention to a series of inquiries that may and, in our view, still should be asked about a supposed, unique and definitive political doctrine of Plato. Then, initially, the following question is raised: The Re-public, one of the most famous and commented dialogues written by Plato, would be in fact the only moment of "his" work in which this author would express "his" political theory (communist)? Supported by Hector Benoit's immanentist reading and interpretation of the Platonic dialogues, we hypothetize that Plato, not being Socrates, exposed ­ through a character called Athenian ­ in his last dialogue, TheLaws, in the temporality of the lexis, a project of city radically different from that on The Republic. Such a project is based on the unity of contradictories for the educational formation of the inhabitants of a city composed of friends who really had all things in common; city that should be put into practice, and not just in the metaphysical soul of the philosopher, as Socrates idealistically proposed in The Republic. Thus, far from having abandoned, as some interpreters argue, his youthful communist positions, Plato would have in fact found them, at the end of his life, in a more rigorously determined way. At the end of our article, Marx and Lenin take on the leading role, which suggests that political theory is one of the guiding threads of the millennial dialectical tradition


Subject(s)
Philosophy , Politics , Communism
3.
Med. crít. (Col. Mex. Med. Crít.) ; 36(8): 521-527, Aug. 2022. tab, graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1506683

ABSTRACT

Resumen: El uso de la pausa al final de la inspiración (PFI) en ventilación mecánica data de hace más de 50 años y con mayor impulso en la década de los 70, se le atribuye una mejoría en la presión parcial de oxígeno arterial (PaO2) al incrementar la presión media de la vía aérea (Pma), mayor aclaramiento de la presión parcial de dióxido de carbono arterial (PaCO2) y permite la monitorización de la presión meseta (Pmeseta) en la mecánica ventilatoria; sin embargo, los estudios clínicos sobre su uso son escasos y controversiales. En este artículo se abordan los mecanismos fisiológicos, fisiopatológicos y la evidencia sobre el uso de la PFI en ventilación mecánica (VM).


Abstract: The use of the end inspiratory pause (EIP) in mechanical ventilation has been going on for more than 50 years and with greater momentum in the 1970s, an improvement in the partial pressure of arterial oxygen (PaO2) is attributed to the increase mean airway pressure, greater clearance of partial pressure of arterial carbon dioxide and allows monitoring of plateau pressure in ventilatory mechanics; However, the Clinical studies on its use are few and controversial. This article addresses the physiological and pathophysiological mechanisms and the evidence on the use of EIP in mechanical ventilation.


Resumo: A utilização da pausa ao final da inspiração (PFI) na ventilação mecânica remonta a mais de 50 anos e com maior impulso na década de 70, atribui-se uma melhora na pressão parcial de oxigênio arterial (PaO2) pelo aumento da pressão média das vias aéreas (Pma), uma maior depuração da pressão parcial de dióxido de carbono arterial (PaCO2) e permite a monitorização da pressão de platô (Pplateau) na mecânica ventilatória, porém estudos Os dados clínicos sobre seu uso são escassos e controversos. Este artigo aborda os mecanismos fisiológicos e fisiopatológicos e as evidências sobre o uso do PFI na ventilação mecânica (VM).

4.
An. Facultad Med. (Univ. Repúb. Urug., En línea) ; 8(2): e301, dic. 2021. ilus, tab
Article in Spanish | LILACS, UY-BNMED, BNUY | ID: biblio-1358052

ABSTRACT

Objetivo: El objetivo del presente estudio es explorar y describir resultados y experiencias en el tratamiento de las fracturas de platillo tibial Schatzker1 I-IV con asistencia artroscópica para obtener reducción como parte de la técnica de fijación interna (ARIF). Metodología: Se realizó una búsqueda sistematizada en diferentes motores de búsqueda como Pubmed y Lilacs. Se buscó con la misma metodología por 2 revisores independientes utilizando términos MESH "Tibial Fracture", "Arthroscopic". Se incluyeron artículos publicados en los últimos 5 años (2014 a Setiembre 2020), que muestren resultados clínicos de los procedimientos, en inglés o español, en humanos y mayores de 18 años. Resultados: Siguiendo los criterios de inclusión se identificaron 114 títulos, y finalmente 9 artículos fueron incluidos en nuestra revisión sistematizada. De los 9 artículos revisados 5 corresponden a series de casos con un nivel de evidencia IV, 3 corresponden a estudios comparativos retrospectivos entre técnicas de reducción abierta y fijación interna (ORIF) y ARIF con nivel de evidencia III y un estudio corresponde a un nivel de evidencia I. Un total de 217 pacientes fueron intervenidos mediante ARIF en nuestra revisión, el tiempo promedio de seguimiento fue de 24.9 meses (12-90 m), en cuanto al tipo de fractura las más frecuentes fueron las fracturas de platillo tibial Schatzker II y III, la lesión asociada más frecuente fue la lesión meniscal seguida de la rotura del ligamento cruzado anterior. En cuanto al porcentaje total de resultados obtenidos independientemente de cada score utilizado, el 98% aproximadamente obtuvo resultados buenos o excelentes. El porcentaje de complicaciones operadas con asistencia artroscópica resultó ser aproximadamente del 6.5%, siendo la complicación más frecuente la trombosis venosa profunda con 6 casos. Conclusiones: De nuestra revisión podemos concluir que la asistencia artroscópica es útil en el tratamiento de las fracturas de platillo tibial Schatzker I-IV, siendo una técnica que provee resultados funcionales satisfactorios, sin incrementar el número de complicaciones y permite tratar lesiones asociadas en el mismo acto.


Objective: The objective of this study is to explore the experience and the results of Schatzker1 I-IV tibial plateau fractures internal fixation technique (ARIF) with arthroscopic assistance Methodology: A systematic review was carried out in different search engines such as Pubmed and Lilacs. The same methodology was applied by two independent reviewers using MESH terms "Tibial Fracture", "Arthroscopic". Articles published in the last 5 years (2014 to September 2020) were included, showing clinical results of the procedures, in English or Spanish, in humans and over 18 years of age. Results: Following the inclusion criteria, 114 titles were identified, and finally 9 articles were included in our systematic review. Of the 9 articles reviewed, 5 were case series (level of evidence IV), 3 retrospective comparative studies between open reduction and internal fixation techniques (ORIF) and ARIF with level of evidence III and one study was level of evidence I. A total of 217 patients underwent ARIF surgery in our review, the average follow-up time was 24.9 months (12-90 m), in terms of the type of fracture, the most frequent were Schatzker II tibial plateau fractures and III, the most frequent associated injury was meniscal injury followed by anterior cruciate ligament tear. Regarding the total percentage of results obtained independently of each score used, approximately 98% obtained good or excellent results. The percentage of complications with arthroscopic assistance turned out to be approximately 6.5%, the most frequent complication being deep vein thrombosis with 6 cases. Conclusions: From our review we can conclude that arthroscopic assistance is useful in the treatment of Schatzker I-IV tibial plateau fractures, since it provides satisfactory functional results, without increasing the number of complications and allows treating associated injuries simultaneously.


Objetivo: o objetivo deste estudo é explorar e descrever os resultados e experiências no tratamento das fraturas do planalto tibial de Schatzker1 I-IV com auxílio artroscópico para obter redução como parte da técnica de fixação interna (ARIF). Metodologia: : Foi realizada uma busca sistemática em diferentes motores de busca, como Pubmed e Lilacs. Foi pesquisado com a mesma metodologia por 2 revisores independentes usando os termos do MESH "Tibial Fracture", "Arthroscopic". Foram incluídos artigos publicados nos últimos 5 anos (2014 a setembro de 2020), mostrando resultados clínicos dos procedimentos, em inglês ou espanhol, em humanos e maiores de 18 anos. Resultados: Seguindo os critérios de inclusão, 114 títulos foram identificados e, finalmente, 9 artigos foram incluídos em nossa revisão sistemática. Dos 9 artigos revisados, 5 correspondem a séries de casos com nível de evidência IV, 3 correspondem a estudos comparativos retrospectivos entre técnicas de redução aberta e fixação interna (ORIF) e ARIF com nível de evidência III e um estudo corresponde a nível de evidência . evidências I. Um total de 217 pacientes foram submetidos a ARIF em nossa revisão, o tempo médio de acompanhamento foi de 24,9 meses (12-90 m), em termos do tipo de fratura, as mais frequentes foram as fraturas do planalto tibial de Schatzker II e III , a lesão associada mais frequente foi a lesão meniscal seguida de ruptura do ligamento cruzado anterior. Em relação ao percentual total de resultados obtidos independentemente de cada escore utilizado, aproximadamente 98% obtiveram resultados bons ou excelentes. O percentual de complicações operadas com assistência artroscópica revelou-se em torno de 6,5%, sendo a complicação mais frequente a trombose venosa profunda com 6 casos. Conclusões: Da nossa revisão podemos concluir que a assistência artroscópica é útil no tratamento das fraturas do planalto tibial de Schatzker I-IV, sendo uma técnica que fornece resultados funcionais satisfatórios, sem aumentar o número de complicações e permite tratar lesões associadas no mesmo ato.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Arthroscopy/methods , Tibial Fractures/surgery , Arthroscopy/adverse effects , Tibial Fractures/classification
5.
Malaysian Journal of Health Sciences ; : 117-126, 2021.
Article in English | WPRIM | ID: wpr-964057

ABSTRACT

@#This is a retrospective study, the organ doses of the bladder and the rectum were compared between routine PLATO V14.2.3 (Nucletron B.V., Veenendaal, The Netherlands) and newer version software Oncentra MasterPlan (OMP) V4.3 (Nucletron B.V., Veenendaal, The Netherlands) treatment planning systems (TPS). The treatment data of 32 intracavitary brachytherapy patients at Hospital Universiti Sains Malaysia from January 2010 to June 2015 were used. These data sets were used for catheter reconstruction for both PLATO and OMP TPS followed by independent verification using Excel. There was no significant difference in mean doses to organs at risk (OARs) that calculated by both TPS (p>0.05). The mean percentage of doses calculated by PLATO TPS for bladder and rectum were 66.58 ± 27.42% and 46.27 ± 14.47%, respectively. While, the mean percentage of doses for bladder and rectum calculated by OMP TPS were 65.68 ± 24.24% and 46.46 ± 16.66%, respectively. The mean percentage difference in doses comparison between independent verification calculation and PLATO TPS was 1.96 ± 6.00% and then became 6.37 ± 5.17% when it was compared with OMP TPS. Overall, the dose calculation differences for both versions of TPS were within the range recommended by Nuclear Regulatory Commission (NRC). The dose calculations of the two treatment planning systems showed good agreement and both could be used in planning intracavitary brachytherapy for cervical cancer. Whereas, Excel based independent verification is suitable to be implemented as routine dose verification programme prior to treatment delivery.

6.
Rev. psicanal ; 27(3): 605-625, Dezembro 2020.
Article in Portuguese | LILACS, INDEXPSI | ID: biblio-1252774

ABSTRACT

Objetivamos compreender o termo desejo do psicanalista enquanto direção ética da psicanálise. Para isso, o texto partirá de contribuições da conceituação do termo desejo em Freud como introdução ao termo desejo do psicanalista nomeado por Lacan, lugar esvaziado de intenções pessoais e de promessas de felicidade ao seu analisante. Ao longo do trabalho, serão revisitados alguns pontos essenciais da clássica obra literária O banquete de Platão de acordo com Lacan, destacando a relação de Sócrates e Alcibíades como possibilidade de contraponto da práxis psicanalítica. Em uma correlação com essa práxis, Sócrates foi colocado no lugar de objeto perdido, objeto agalmático para Alcibíades, ocupando um lugar de objeto na transferência do amor depositado por este último. Diante da sua sustentação e do desejo de não ceder ao discurso sedutor deste participante, Sócrates relança-o ao seu próprio desejo, tal como é recomendado a um psicanalista na condução de um tratamento. Finalmente, esse exemplo irá nos levar a uma reflexão quanto ao rigor ético da psicanálise como norteadora do desejo do psicanalista (AU)


We aim to understand the term psychoanalyst's desire as an ethical direction of psychoanalysis. For this, the text will start from contributions of the conceptualization of the term desire in Freud as an introduction to the term desire of the psychoanalyst named by Lacan, a place emptied of his personal intentions and promises of happiness to his analysand. Throughout the work, some essential points of the classic literary work Plato's The banquet will be revisited by Lacan, highlighting the relationship between Socrates and Alcibiades as a possibility for counterpointing psychoanalytic praxis. In a correlation with this praxis, Socrates may have been placed in the place of a lost object, an agalmatic object for Alcibiades, who occupied an object`s place in the transference and love deposited by the latter. Given the support and desire not to give in to this participant's seductive speech, Socrates relaunches it to his own desire as recommended by a psychoanalyst when conducting a treatment. Finally, this example will enlighten us for a reflection on the ethical rigor of psychoanalysis as guiding the psychoanalyst's desire (AU)


Nuestro objetivo es entender el término deseo del psicoanalista como una dirección ética del psicoanálisis. Para esto, el texto comenzará con contribuciones de la conceptualización del término deseo en Freud como una introducción al término deseo del psicoanalista nombrado por Lacan, un lugar vaciado de sus intenciones personales y promesas de felicidad para su analizante. Se explorarán algunos puntos esenciales de la obra literaria clásica El banquete de Platón por Lacan, destacando la relación entre Sócrates y Alcibíades como una posibilidad de contrapunto a la praxis psicoanalítica. En una correlación con esta praxis, Sócrates puede haber sido colocado en el lugar de objeto perdido, objeto agalmático para Alcibíades, quien ocupó un lugar de objeto en la transferencia y el amor depositado por este último. Delante su apoyo y deseo de no ceder ante el discurso seductor de este participante, Sócrates lo relanza a su propio deseo según lo recomendado por un psicoanalista cuando realiza el tratamiento. Finalmente, este ejemplo nos iluminará para reflexionar sobre el rigor ético del psicoanálisis como guía para el deseo del psicoanalista (AU)


Subject(s)
Volition , Aspirations, Psychological
7.
Coluna/Columna ; 19(3): 213-217, July-Sept. 2020. tab
Article in English | LILACS | ID: biblio-1133582

ABSTRACT

ABSTRACT Objective To evaluate whether vertebral endplate signal changes (VESCs) influence the prognosis of patients submitted to conservative or surgical treatment for low back pain and lumbosciatica. Methods Study with 241 patients who underwent conservative treatment, infiltration or surgery with 12 months of follow-up. They were evaluated for pain by the Visual Analog Scale for Pain (VAS), for function by the Roland Morris questionnaire and for quality of life by the EuroQoI5 (EQ-5D). Results The VESCs did not have a significant effect on the treatment responses for the VAS (F = 0.03; P = 0.97), Roland Morris (F = 0.51; P = 0.60) and EQ-5D (F = 2.67; P = 0.07) variables, nor was there any interaction between VESC and treatment for VAS (F = 2.15; P = 0.08), Roland Morris (F = 1.55; P = 0.19) and EQ-5D (F = 2.15; P = 0.08). There was a significant effect for all treatments, however, the effect of the surgical procedure was superior when compared to the others (P <0.001). The VESC frequency was 48.33% for type 0, 29.17% for type I and 22.50% for type II. Conclusions The presence of VESC and its different types is not associated with a worse prognosis, nor was a higher prevalence of VESC observed in the patients with low back pain and lumbosciatica. Level of Evidence II; Retrospective cohort study.


RESUMO Objetivo Avaliar se as alterações de sinal do platô vertebral (ASPV) influenciam o prognóstico de pacientes submetidos ao tratamento conservador ou cirúrgico em lombalgia e lombociatalgia. Métodos Estudo com 241 pacientes submetidos ao tratamento conservador, infiltração ou cirurgia, com acompanhamento de 12 meses. Foram avaliados pela Escala Visual Analógica (EVA) da Dor, quanto à função, pelo questionário Roland Morris e quanto à qualidade de vida, pelo questionário EuroQoI5 (EQ-5D). Resultados As ASPV não tiveram efeito significante nas respostas do tratamento para as variáveis EVA (F = 0,03; P = 0,97), Roland Morris (F = 0,51; P = 0,60) e EQ-5D (F = 2,67; P = 0,07), bem como não houve interação de ASPV e tratamento para EVA (F = 2,15; P = 0,08), Roland Morris (F = 1,55; P = 0,19) e EQ-5D (F = 2,15; P = 0,08). Houve efeito significante para todos os tratamentos; entretanto, o efeito do procedimento cirúrgico foi superior quando comparado aos demais (P < 0,001). A frequência de ASPV tipo 0 foi 48,33%, tipo I foi 29,17% e tipo II foi 22,50%. Conclusões A presença de ASPV e seus diferentes tipos não estão associados a prognóstico pior, bem como não se demonstrou maior prevalência de ASPV nos pacientes com lombalgia e lombociatalgia. Nível de Evidência II; Estudo de coorte retrospectivo.


RESUMEN Objetivo Evaluar si las alteraciones de señal de la meseta vertebral (ASMV) influyen en el pronóstico de los pacientes sometidos a tratamiento conservador o quirúrgico en lumbalgia y lumbociatalgia. Métodos Estudio con 241 pacientes sometidos al tratamiento conservador, infiltración o cirugía, con acompañamiento de 12 meses. Se evaluaron a través de la Escala Visual Analógica del Dolor (EVA), cuanto a la función, por el cuestionario Roland Morris y cuanto a la calidad de vida por el cuestionario EuroQoI5 (EQ-5D). Resultados Las ASMV no tuvieron efecto significativo en las respuestas del tratamiento para las variables EVA (F = 0,03; P = 0,97), Roland Morris (F = 0,51; P = 0,60) y EQ-5D (F = 2,67; P = 0,07), así como no hubo interacción de ASMV y tratamiento para EVA (F = 2,15; P = 0,08), Roland Morris (F = 1,55; P = 0,19) y EQ-5D (F = 2,15; P = 0,08). Hubo efecto significativo para todos los procedimientos, entretanto, el efecto del procedimiento quirúrgico fue superior cuando comparado a los demás (P <0,001). La frecuencia de ASMV para el tipo 0 fue 48,33%, tipo I 29,17% y tipo II 22,50%. Conclusiones La presencia de ASMV y sus diferentes tipos no están asociados a pronóstico peor, bien como no se demostró mayor prevalencia de ASMV en los pacientes con lumbalgia y lumbociatalgia. Nivel de Evidencia II; Estudio de cohorte retrospectivo.


Subject(s)
Humans , Low Back Pain , Sciatica , General Surgery , Conservative Treatment
8.
Rev. colomb. psiquiatr ; 49(2): 121-126, abr.-jun. 2020. tab
Article in English | LILACS, COLNAL | ID: biblio-1115653

ABSTRACT

ABSTRACT In 2018 the academy will celebrate the 200th anniversary of the publication of the seminal work of Arthur Schopenhauer (1788-1860): The World as Will and Representation (Idea). Schopenhauer is known as the "philosopher of pessimism" and as the "psychologist of the will". His thinking is formally absent in the psychiatric education curricula, which could be enriched by the philosopher's work. Regarding psychiatry's theoretical foundations, Schopenhauer: a) anticipated several issues of species' origin and evolution, which are used in the contemporary understanding of disease development; b) anticipated some attributes of the psychodynamic and cognitive unconscious when referring to the irrational features of the will; c) foresaw the current concept of the embodied mind, which emphasizes the role of the body's structure and dynamics in cognition instead of that of a transcendental reason; d) proposed a simplified and heuristic model of mind, comprising the senses, understanding and reason; at a pragmatic level, particularly concerning psychotherapy, the philosopher e) stated that all human actions spring from three fundamental sources: egoism, malice and compassion; he also speculated about the role of unconscious repression in the genesis of mental illnesses; and finally, f) emphasized the ubiquity of suffering and the insatiability of desire, which unavoidably leads to egocentrism. In this regard he highly valued contemplation of art and nature as a way of dissociating knowledge from desire, and thus allowing the development of compassion and asceticism. This was considered by the philosopher to be "denial of the will", and a path for individual salvation and well-being. In contemporary psychiatry, this metaphysical proposal may be reformulated in terms of promoting cooperation and healthy austerity as a non-specific component of most psychotherapies and educational models. Schopenhauer's thinking may enrich psychiatric training and personal well-being.


RESUMEN En 2018 la academia celebra el bicentenario de la publicación de la obra capital de Arthur Schopenhauer (1788-1860) El mundo como voluntad y representación (idea). Schopenhauer es conocido como el «filósofo pesimista¼ y el «psicólogo de la voluntad¼. Su obra está formalmente ausente en el currículo de la formación en Psiquiatría, que puede enriquecerse con las siguientes contribuciones del filósofo. Con relación a los fundamentos teóricos de la Psiquiatría, Schopenhauer: a) anticipó diversos aspectos del origen y la evolución de las especies que hoy se utilizan para la comprensión del desarrollo de la enfermedad; b) anticipó algunos atributos del inconsciente dinámico y cognitivo cuando se refirió a los aspectos no racionales de la voluntad; c) predijo el concepto contemporáneo de la mente corporizada, cuando enfatizó con relación a la cognición el papel de la estructura y la dinámica corporales, en lugar de una razón trascendental; d) propuso un modelo simplificado y heurístico de la mente, que comprende los sentidos, el entendimiento y la razón; en un sentido pragmático, referido particularmente a la psicoterapia, el filósofo: e) afirmó que todas las acciones humanas se originan de 3 fuentes fundamentales: egoísmo, maldad y compasión; también especuló acerca del papel de la represión inconsciente en la génesis de las enfermedades mentales, y para terminar, f) enfatizó la ubicuidad del sufrimiento y la insaciabilidad del deseo, lo que inevitablemente lleva al egocentrismo. En este sentido, valoró la contemplación artística y de la naturaleza como una vía para disociar el conocimiento del deseo y así permitir el desarrollo de la compasión y el ascetismo. El filósofo lo consideraba la "negación de la voluntad" y un camino para la salvación y el bienestar individual. En la Psiquiatría contemporánea, esta propuesta metafísica puede reformularse como la promoción de la cooperación y de una austeridad sana, como un componente inespecífico de la mayoría de las psicoterapias y los modelos educativos. El pensamiento de Schopenhauer puede enriquecer la instrucción en Psiquiatría y el bienestar personal.


Subject(s)
Humans , Psychiatry , Work , Knowledge , Psychotherapy , Repression, Psychology , Stress, Psychological , Thinking , Models, Educational , Ethics , Anniversaries and Special Events
9.
Rev. Pesqui. Fisioter ; 10(2): 182-187, Maio 2020. tab, ilus
Article in English, Portuguese | LILACS | ID: biblio-1223559

ABSTRACT

Determinar prevalência de fraturas de platô tibial em pacientes internos em um Hospital Público do Piauí. MATERIAIS E MÉTODOS: Foram analisados 50 prontuários com Fraturas de Platô Tibial de Janeiro de 2017 a Janeiro de 2018. O instrumento de análise foi um questionário composto por informações relevantes, como: sexo, idade, raça, mecanismo de lesão, tipos de fratura e lado, para a coleta dos dados. Para análise dos dados utilizou-se a estatística descritiva com cálculos de médias, desvio padrão e frequências absoluta e relativa. RESULTADOS: A maior incidência das fraturas foi no sexo masculino (72%). A média de idade dos pacientes foi de 38 ± 13,86 anos, vítimas principalmente de acidentes automobilísticos (66%), sendo o lado mais acometido o direito (70%) com a incidência maior de fratura oblíqua (48%). CONCLUSÃO: há maior prevalência de fraturas do platô tibial no sexo masculino, faixa etária de 19-29 anos, vítima de acidente automobilísticos, com fraturas oblíquas.


To determine the prevalence of tibial plateau fractures in internal patients at a Public Hospital of Piauí. MATERIALS AND METHODS: Fifty medical records with Tibial Plateau Fractures from January 2017 to January 2018 were analyzed. The analysis instrument was a questionnaire composed of relevant information, such as: sex, age, race, injury mechanism, types of fracture and affected side, for data collection. For data analysis we used descriptive statistics with calculations of means, standard deviation and absolute and relative frequencies. RESULTS: The highest incidence of fractures was in males (72%). The mean age of the patients was 38 ± 13.86 years, mainly victims of automobile accidents (66%), with the right side most affected (70%) with the highest incidence of oblique fracture (48%). CONCLUSION: there is a higher prevalence of fractures of the tibial plateau in males, aged 19-29 years, victim of automobile accidents, with oblique fractures.


Subject(s)
Fractures, Bone , Tibial Fractures , Hospitals, Public
10.
Rev. Col. Bras. Cir ; 47: e20202546, 2020. graf
Article in English | LILACS | ID: biblio-1136613

ABSTRACT

ABSTRACT The aim of this study was to evaluate the biomechanical role of both a non-locking two-hole small fragment dynamic compression plate with 3.5-mm screws and a 4.5-mm cortical screw with a washer applied to a Schatzker type-I tibial plateau fracture. Sixteen right synthetic tibiae were used to create an anterolateral shear tibial plateau fracture (Schatzker type-I fracture). Eight models were fixed with a small fragment non-locked straight dynamic compression plate with one 3.5-mm bicortical screw (plate-screw construction) and eight models were fixed with a 4.5-mm cortical screw and a washer (screw-washer construction), both inserted at 1.0 mm distal to the apex of the fracture. Specimens were tested up to the onset of yielding at a constant strain rate of 5.0-mm/min. Stiffness ranged from 311.83 N/mm to 199.54 N/mm, with a mean + SD of 260.32 + 33.8 N/mm in the plate-screw construction, and from 290.34 N/mm to 99.16 N/mm, with a mean + SD of 220.46 + 63.12 N/mm in screw-washer construction. There was no significant difference (p=0.172). Use of a two-hole small-fragment non-locked plate with one 3.5-mm cortical screw or a 4.5-mm cortical screw with a washer applied at 1.0 mm distal to the apex of the fracture as buttressing present similar stiffness in terms of preventing axial displacement in synthetic tibiae models tested up to the onset of yielding.


RESUMO O objetivo do estudo foi avaliar o comportamento biomecânico de dois tipos de fixação: placa de compressão dinâmica de pequenos fragmentos, não bloqueada com parafuso de 3,5mm e parafuso cortical de 4,5mm com arruela, ambos posicionados no vértice de fratura do platô tibial do tipo I de Schatzker. Dezesseis tíbias sintéticas foram utilizadas para criar uma fratura por cisalhamento na face ântero-lateral do platô tibial (tipo I de Schatzker). Oito modelos foram fixados com placa de compressão dinâmica de pequenos fragmentos não bloqueada com parafuso de 3,5mm, inserido 1,0mm distal ao vértice da fratura (construção placa-parafuso), e oito modelos foram fixados com parafuso cortical de 4,5mm com arruela, inserido 1,0mm distal ao vértice da fratura (construção parafuso-arruela). Os modelos foram testados em compressão axial até o início da falha mecânica na interface construção-osso, com taxa de deformação constante de 5,0mm/min. A rigidez variou de 311,83 N/mm a 199,54 N/mm, com média + DP de 260,32 + 33,8 N/mm nos modelos da construção placa-parafuso, e de 290,34 N/mm a 99,16 N/mm, com média + DP de 220,46 + 63,12 N/mm nos modelos da construção parafuso-arruela. Não houve diferença estatisticamente significativa (p=0,172). A utilização de placa de compressão dinâmica de pequenos fragmentos não bloqueada com parafuso de 3,5mm ou de parafuso cortical de 4,5mm com arruela, posicionados no vértice da fratura do platô tibial do tipo I de Schatzker, apresenta rigidez similar na prevenção do desvio axial da fratura.


Subject(s)
Humans , Tibial Fractures/surgery , Fracture Fixation, Internal/methods , Bone Plates , Bone Screws , Models, Anatomic
11.
Chinese Journal of Burns ; (6): 752-756, 2019.
Article in Chinese | WPRIM | ID: wpr-796816

ABSTRACT

Objective@#To explore the effects of application of Plato analysis combined with plan-do-check-action (PDCA) cycle in scientific research management of nurses with primary position title.@*Methods@#Twenty-six nurses with primary position title were recruited in this self pre- and post-control study. From January 2012 to December 2013, they were guided by normal scientific research management. In January 2014, the factors which hinder these nurses from writing papers were investigated by the questionnaire titled " the impediments that hinder nurses with primary position title from writing papers" . Based on " twenty-eighty percent laws" of Plato analysis method, the main influencing factors which hinder nurses with primary position title from writing papers were " had no idea" and " did not know how to write although with ideas" . From January 2014 to December 2015, based on the results of the survey and combined with PDCA cycle method, interventions were planned, carried out, analyzed by stage, and then improved continuously. Impediments which hinder writing papers of 26 nurses in January 2014 and December 2015, specific scientific research achievement, total scientific research achievement, and average scientific research achievement of these 26 nurses before intervention (from January 2012 to December 2013) and after intervention (from January 2014 to December 2015) were analyzed. Data were processed with McNemar exact probability test, Wilcoxon signed rank sum test.@*Results@#(1) The cumulative percentages of main impediments " had no idea" and " did not know how to write although with ideas" were decreased from 76.93% in January 2014 to 23.07% in December 2015. The number of nurses who " had no idea" was significantly reduced from 14 in January 2014 to 4 in December 2015 (P<0.01). The total number of nurses who had impediments which hinder writing papers was significantly reduced from 26 in January 2014 to 10 in December 2015 (P<0.01). (2) The total scientific research achievement and average scientific research achievement of the 26 nurses were significantly increased from 5 before intervention to 32 after intervention and 0.19 before intervention to 1.23 after intervention, respectively (Z=-4.838, -3.703, P<0.01). Among which, numbers of specific scientific research achievement of papers published in Journals of Statistic Source, papers published in other journals, science and technology awards, fund projects, national utility model patents, and patents for invention after intervention were all increased than those before intervention (P<0.05 or P<0.01).@*Conclusions@#Plato analysis can accurately analyze the main impediments that hinder nurses with primary position title from writing papers. Plato analysis combined with PDCA cycle can improve the overall ability of scientific research of nurses with primary position title and affect the achievements in nursing scientific research, which is worthy of promotion.

12.
Genomics, Proteomics & Bioinformatics ; (4): 319-331, 2019.
Article in English | WPRIM | ID: wpr-772930

ABSTRACT

Proteins usually associate with other molecules physically to execute their functions. Identifying these interactions is important for the functional analysis of proteins. Previously, we reported the parallel analysis of translated ORFs (PLATO) to couple ribosome display of full-length ORFs with affinity enrichment of mRNA/protein/ribosome complexes for the "bait" molecules, followed by the deep sequencing analysis of mRNA. However, the sample processing, from extraction of precipitated mRNA to generation of DNA libraries, includes numerous steps, which is tedious and may cause the loss of materials. Barcoded PLATO (PLATO-BC), an improved platform was further developed to test its application for protein interaction discovery. In this report, we tested the antisera-antigen interaction using serum samples from patients with inclusion body myositis (IBM). Tripartite motif containing 21 (TRIM21) was identified as a potentially new IBM autoantigen. We also expanded the application of PLATO-BC to identify protein interactions for JQ1, single ubiquitin peptide, and NS5 protein of Zika virus. From PLATO-BC analyses, we identified new protein interactions for these "bait" molecules. We demonstrate that Ewing sarcoma breakpoint region 1 (EWSR1) binds to JQ1 and their interactions may interrupt the EWSR1 association with acetylated histone H4. RIO kinase 3 (RIOK3), a newly identified ubiquitin-binding protein, is preferentially associated with K63-ubiquitin chain. We also find that Zika NS5 protein interacts with two previously unreported host proteins, par-3 family cell polarity regulator (PARD3) and chromosome 19 open reading frame 53 (C19orf53), whose attenuated expression benefits the replication of Zika virus. These results further demonstrate that PLATO-BC is capable of identifying novel protein interactions for various types of "bait" molecules.

13.
Ágora (Rio J. Online) ; 21(3): 397-405, set.-dez. 2018.
Article in Portuguese | LILACS, INDEXPSI | ID: biblio-963598

ABSTRACT

Resumo: Buscamos desenvolver a questão acerca da filiação platônica da psicanálise freudiana e lacaniana. Desta maneira, nossa primeira tarefa é questionar a imagem de Platão como filósofo dogmático, preocupado com a transcendência da Ideia e desprezando a singularidade sensível. Pelo contrário, veremos como é através de uma contradição imanente à filosofia platônica que podemos compreender como a psicanálise pode ser filiada ao projeto platônico, mas apenas se admitirmos que a verdade do discurso de Platão aparece em suas falhas inerentes. Procuraremos delinear o espaço da verdade na psicanálise como sendo causado pelo encontro com o que Lacan chamou de real, buscando compreender as relações do real com o platonismo.


Abstract: We seek to develop, in this paper, the question of the Platonic alliance of Freudian and Lacanian psychoanalysis. Thus, our first task is to question the image of Plato as a dogmatic philosopher, concerned about the transcendence of the Ideia and ignoring sensitive singularity. On the contrary, we'll look that is through an immanent contradiction in the Platonic philosophy that we can understand how psychoanalysis can be affiliated with the Platonic project, but only if we admit that the truth of Plato's discourse appears in its inherent flaws. We will seek to delineate the space of truth in psychoanalysis as being caused by the encounter with what Lacan called the real, trying to understand the relationship between the concept of real and platonic philosophy.


Subject(s)
Humans , Psychoanalytic Interpretation , Truth Disclosure
14.
Pesqui. vet. bras ; 38(6): 1190-1195, jun. 2018. tab, graf
Article in English | LILACS, VETINDEX | ID: biblio-955454

ABSTRACT

The influence of the proximal tibial angles in the cranial cruciate ligament (CCL) rupture in dogs is still controversial, and little is known regarding this topic in cats. The aim of this study was to evaluate and compare the angles of the proximal portion of the tibia in dogs and cats with and without CCL rupture. Retrospective and prospective radiographs of the stifle joints were obtained and divided into four groups. Group 1 was composed of 70 stifle joint images of dogs without orthopedic disorders (healthy dogs), group 2 had 70 stifle joint images of dogs with CCL rupture, group 3 had 50 stifle joint images of cats without orthopedic disorders (healthy cats) and group 4 had 25 stifle joint images of cats with CCL rupture. Radiographs were taken with the stifle joint in the mediolateral projection, positioned at the angle of hind limb support. Between the two groups of dogs evaluated, the dogs with CCL rupture had statistically greater tibial plateau angle (TPA) compared with healthy dogs. No difference was shown in relation to the TPA between healthy cats and cats with CCL rupture. In relation to the patellar ligament angle by tibial plateau method the values for the healthy dogs were significantly higher than those for the CCL ruptured dogs. Similarly, healthy cats had significantly higher mean values than cats with CCL rupture. In the patellar ligament angle by common tangent method there was no significantly difference between the two groups of dogs. Between the two groups of cats, animals with CCL rupture had statistically higher mean values than healthy cats. In general, the groups of dogs showed higher mean values than the groups of cats. For the patellar ligament insertion angle (PLIA) healthy dogs showed a significantly higher mean than dogs with CCL rupture. There was no significant difference between the groups of cats. In conclusion, the TPA and the PLIA possibly influence the etiology of CCL rupture in dogs but not in cats. The low patellar ligament angle measured by common tangent method may favorably influence the reduced incidence of CCL rupture in cats.(AU)


A influência dos ângulos da parte proximal da tíbia sobre a ruptura do ligamento cruzado cranial (LCC) em cães é ainda controversa, e pouco é descrito sobre este tópico em gatos. O objetivo deste estudo foi avaliar e comparar os ângulos da tíbia proximal em cães e gatos, ambas as espécies com e sem ruptura do LCC. Foram obtidos exames radiográficos retrospectivos e prospectivos das articulações do joelho e divididos em quatro grupos: no grupo 1 foram incluídas 70 imagens radiográficas da articulação do joelho de cães sem distúrbios ortopédicos (cães saudáveis), no grupo 2 foram 70 imagens radiográficas articulação do joelho de cães com ruptura do LCC, no grupo 3 foram 50 imagens radiográficas da articulação do joelho de gatos sem distúrbios ortopédicos (gatos saudáveis), e no grupo 4 foram 25 imagens radiográficas articulação do joelho de gatos com ruptura do LCC. As imagens radiográficas da articulação do joelho foram obtidas na projeção mediolateral, mantendo-se a articulação posicionada na angulação de apoio do membro pélvico. Em relação ao ângulo do platô tibial (APT), os cães com ruptura do LCC tiveram estatisticamente maiores valores médios do APT quando comparados aos cães saudáveis. Não foi observada diferença significativa em relação ao APT entre os gatos saudáveis e os gatos com ruptura do LCC. Em relação ao ângulo do ligamento patelar mensurado pelo método do platô tibial, os valores médios observados para os cães saudáveis foram significativamente mais elevados do que os valores encontrados para os cães com ruptura do LCC. De forma semelhante, os gatos saudáveis também apresentaram valores médios mais elevados do que os gatos com ruptura do LCC. Para o ângulo do ligamento patelar mensurado pelo método da tangente comum, não foram observadas diferenças significativas entre os dois grupos de cães. No entanto, entre os dois grupos de gatos, os animais com ruptura do LCC apresentaram valores médios significativamente mais elevados do que os gatos saudáveis. Em geral, os grupos de cães demonstraram valores médios mais elevados quando comparados aos grupos de gatos. Em relação ao ângulo de inserção do ligamento patelar (AILP), os cães saudáveis apresentaram valores médios significativamente mais elevados do que os cães com ruptura do LCC. No entanto, não foi observada diferença significativa entre os dois grupos de gatos. Em conclusão, o APT e o AILP possivelmente exercem influência na etiologia da ruptura do LCC em cães, mas não influenciam nos gatos. Em gatos, os reduzidos ângulos do ligamento patelar observados pelo método da tangente comum podem influenciar favoravelmente na baixa incidência da ruptura do LCC nessa espécie.(AU)


Subject(s)
Animals , Cats , Dogs , Tibia , Radiography/veterinary , Cats , Patellar Ligament , Dogs
15.
Med. leg. Costa Rica ; 34(1): 92-103, ene.-mar. 2017. tab, ilus
Article in Spanish | LILACS | ID: biblio-841430

ABSTRACT

ResumenLas fracturas de plato tibial representan el 1,2% de las fracturas, se observan predominantemente en dos grupos: en pacientes jóvenes que sufren lesiones de alta energía y en adultos mayores con osteopenia debido a traumas de baja energía. 1,2En el paciente joven es más frecuente la lesión de tejidos blandos debido a la resistencia ósea, mientras en el paciente anciano suele asociarse mayor frecuencia de depresión de la superficie articular.2Las causas asociadas son la compresión axial asociada a varo o valgo, precipitaciones, accidentes de tránsito y actividades deportivas. Las fracturas del plato tibial lateral son más frecuentes que las mediales, debido al valgo fisiológico.1,2 .Se dividen en VI tipos. Los tipos de fracturas V y VI involucran los dos platos tibiales, medial y lateral, por lo que en este tipo de fracturas se observan peores resultados postquirúrgicos. Las consecuencias se deben al tiempo requerido para la recuperación y las secuelas residuales.El presente estudio pretende documentar cuáles son los tratamientos de elección en el Hospital San Juan de Dios y sentar un precedente epidemiológico con datos costarricenses que sirva de base para futuras investigaciones y/o protocolos de tratamiento.Los resultados quirúrgicos se miden de acuerdo a la satisfacción de los pacientes con el proceso quirúrgico y la funcionalidad postquirúrgica, esto debido a que dichas medidas han demostrado poseer mayor utilidad para monitorizar las intervenciones terapéuticas.6,7


AbstractTibialplateau fractures represent 1,2% of all fractures, they are predominant in two groups: young patients who suffer of high-energy trauma and in elderly with osteopenia due to low energy trauma. In young patients, soft tissue trauma is more frequent due to bone resistance, in the elderly it is associated with articular surface depression. Fractures causes are associated with valgus or varus axial compression, precipitation, car accidents and sports. Lateral tibialplateau fractures are more frequent than medial fractures due to physiological valgus.These fractures are divided in VI types, V and VI include both tibialplateau, medial and lateral, having worst post surgical results due to recovery time and residual sequels.This study will evaluate treatment election in Hospital San Juan de Dios and present epidemiological background with costarrican data that will be useful for future investigations and/or treatment protocols.Surgical results are assessed with patient satisfaction with the surgical process and post surgical functionality, because these variables have proven best effect in therapeutical intervention evaluation.


Subject(s)
Humans , Male , Female , Tibial Fractures , Tibial Fractures/classification , Costa Rica , Fractures, Bone , Fracture Fixation, Internal
16.
Arq. bras. med. vet. zootec ; 68(6): 1586-1594, nov.-dez. 2016. tab, ilus
Article in English | LILACS, VETINDEX | ID: biblio-827944

ABSTRACT

There are few studies about the treatment options for cranial cruciate ligament rupture in growing dogs, especially with epiphysiodesis techniques. The aim of this study was to evaluate the electrocautery technique for proximal tibial epiphysiodesis in Labrador retriever puppies. The novel electrocautery technique was compared with the screw technique regarding the efficacy for tibial plateau leveling in growing dogs. Six healthy Labrador retriever puppies were divided into two groups. The screw technique was used in one group and the electrocautery technique was used in the other group. Both proximal tibial epiphysiodesis techniques for tibial plateau leveling were effective in achieving reduced tibial plateau angle and did not cause significant joint changes. The screw technique was more invasive and caused slightly greater morbidity than the electrocautery technique. The electrocautery technique seems to be a good alternative for proximal tibial epiphysiodesis in young dogs.(AU)


São descritos poucos estudos sobre as opções de tratamento para a ruptura do ligamento cruzado cranial em cães na fase de crescimento, especialmente em relação às técnicas de epifisiodese. O objetivo deste estudo foi avaliar a técnica de eletrocauterização para epifisiodese proximal da tíbia em cães filhotes da raça Labrador Retriever. A nova técnica de eletrocauterização foi comparada com a do parafuso em relação à eficácia para nivelamento do platô tibial em cães na fase de crescimento. Seis filhotes saudáveis da raça Labrador foram selecionados e divididos aleatoriamente em dois grupos. A técnica do parafuso foi usada em um grupo, enquanto no outro foi usada a da eletrocauterização. Ambas as técnicas de epifisiodese proximal da tíbia para nivelamento do platô tibial foram eficazes na redução do ângulo do platô tibial e não causaram alterações articulares importantes. A técnica do parafuso foi considerada mais invasiva e causou morbidade um pouco mais acentuada do que a da eletrocauterização. Assim, a técnica da eletrocauterização parece ser uma boa alternativa para a epifisiodese proximal da tíbia em cães jovens.(AU)


Subject(s)
Animals , Dogs , Electrocoagulation/methods , Epiphyses, Slipped/surgery , Knee Joint/surgery , Tibia/injuries , Electrocoagulation/veterinary
17.
Chinese Journal of Practical Nursing ; (36): 2302-2306, 2016.
Article in Chinese | WPRIM | ID: wpr-501922

ABSTRACT

Objective To apply Plato analysis method to clinical cases which were reported from clinical nursing, finding out the key link of the risks which were related to the cases:the key age, the key period, the key spectrum of disease and the key projects, etc. To carry out the feedforward control of the quality of care, and ensure the quality and safety of nursing. Methods A database were set up including clinical special cases, high-risk cases, security hidden danger cases and emergency cases. Thetwo eightprinciple of Plato analysis method was used to find out the main factors, the principal contradiction, the key hazard and the key problems of the cases, etc. The aim was to provide guidelines of risk analysis, risk prevention and risk aversion for nurses, and improve their consciousness of security hidden danger, and reduce security hidden danger cases. Results The results of 207 cases collected from 2014 to 2015 showed that the main risks involved the age groups were 41-80 years old and 21-30 years old. The major risks involved the spectrum of disease were the nervous system, cardiovascular disease, surgical anesthesia related problems, kidney disease, cancer and respiratory system. The major risks involved the time were the midnight, morning and afternoon. The major risks involved the locations were sickroom, emergency room, auxiliary inspection departments and outpatient. The major risks involved items were disease mutation, psychological problems, medication safety and instrument safety, among the disease mutation, timely discovered, rescued 13 patients with heart and breathing pause, stop 13 patients who attempted suicide. Since the Plato analysis method was applied to identify the security risks of the clinical cases, the number of falling, all kinds of pipe shed, skin problems and suicides were decreased from 6, 6, 7, 5 in 2014 to 2, 2, 2, 1 in 2015, declining trend year by year. Conclusions Applying the Plato analysis method to identify the security risks of the clinical cases which can find out the main problems of cases and improve nursing quality and management efficiency.

18.
Arq. bras. med. vet. zootec ; 67(5): 1254-1262, tab, graf
Article in English | LILACS | ID: lil-764440

ABSTRACT

The influence of the proximal tibia conformation in the rupture of the cranial cruciate ligament (CCL) in dogs is still controversial, especially in Labrador Retrievers. The aim of this study was to compare the angles of the proximal tibia between Labrador Retrievers and other large breeds of dogs, both groups with and without CCL rupture. Radiographic images of 64 stifle joints were obtained and divided into four groups of 16 images. Group 1 consisted of Labrador dogs without orthopedic disorders, group 2 consisted of Labrador dogs with CCL rupture, group 3 consisted of dogs of various large breeds without orthopedic disorders, and group 4 consisted of dogs of various large breeds with CCL rupture. The radiographs were performed in mediolateral projection with the stifle joint positioned at an approximate angle of 135°. The tibial plateau angle showed an overall average of 22.17°±4.20°, and there was no statistically significant difference between the groups. The patellar ligament angle in relation to the tibial plateau had a mean of 103°±4.20°, and there was a significant difference between groups 1 and 4. The patellar ligament angle in relation to the common tangent at the tibiofemoral contact point showed an average of 99.06°±6.08°, and there was no difference between the groups. The patellar ligament insertion angle had an overall average of 51.45°±5.06°, and there was a significant difference between the two groups of normal dogs and two groups of ruptured dogs. In conclusion, the tibial plateau angle, the patellar ligament angles and the patellar ligament insertion angle do not seem to be predisposing factors for rupture of the CCL in Labrador Retriever dogs. In general, there seems to be no relationship between the angles of the proximal tibia and the CCL rupture in dogs.


A influência da conformação da porção proximal da tíbia na ruptura do ligamento cruzado cranial (LCC) em cães ainda é controversa, principalmente na raça Labrador Retriever. O objetivo deste estudo foi comparar os ângulos da tíbia proximal entre cães da raça Labrador Retriever e cães de outras raças grandes com e sem ruptura do LCC. Foram selecionadas 64 imagens radiográficas da articulação do joelho de cães, que foram divididas em quatro grupos com 16 imagens cada. O grupo 1 foi formado por cães da raça Labrador sem alterações ortopédicas, o grupo 2 por cães da raça Labrador com ruptura do LCC, o grupo 3 por cães de várias raças grandes sem alterações ortopédicas, e o grupo 4 por cães de diversas raças grandes com ruptura do LCC. Foram realizadas radiografias na projeção mediolateral com a articulação do joelho posicionada em angulação média de 135°. O ângulo do platô tibial apresentou média geral de 22,17°±4,20°, não sendo encontrada diferença estatisticamente significativa entre os grupos. O ângulo do ligamento patelar em relação ao platô tibial apresentou média geral de 103,00°±4,20°, havendo diferença significativa entre os grupos 1 e 4. O ângulo do ligamento patelar em relação à tangente comum no ponto de contato tibiofemoral apresentou média geral de 99.06°±6.08°, não havendo diferença estatística entre os grupos. O ângulo de inserção do ligamento patelar teve média geral de 51.45°±5.06°, com diferença significativa entre os grupos dos cães normais e dos cães com ruptura. Conclui-se que o ângulo do platô tibial, os ângulos do ligamento patelar e o ângulo de inserção do ligamento patelar não parecem ser fatores predisponentes para a ruptura do LCC em cães da raça Labrador Retriever. Em geral, não há relação entre os ângulos da tíbia proximal e a ruptura do LCC em cães.


Subject(s)
Animals , Dogs , Anterior Cruciate Ligament , Knee Joint , Patellar Ligament , Posterior Cruciate Ligament , Tibia , Case-Control Studies
19.
Ciênc. rural ; 44(7): 1204-1209, 07/2014. tab, graf
Article in English | LILACS | ID: lil-718178

ABSTRACT

The aim of this research was to evaluate the influence of the number and position of nutrient levels used in dose-response trials in the estimation of the optimal-level (OL) and the goodness of fit on the models: quadratic polynomial (QP), exponential (EXP), linear response plateau (LRP) and quadratic response plateau (QRP). It was used data from dose-response trials realized in FCAV-Unesp Jaboticabal considering the homogeneity of variances and normal distribution. The fit of the models were evaluated considered the following statistics: adjusted coefficient of determination (R²adj), coefficient of variation (CV) and the sum of the squares of deviations (SSD).It was verified in QP and EXP models that small changes on the placement and distribution of the levels caused great changes in the estimation of the OL. The LRP model was deeply influenced by the absence or presence of the level between the response and stabilization phases (change in the straight to plateau). The QRP needed more levels on the response phase and the last level on stabilization phase to estimate correctly the plateau. It was concluded that the OL and the adjust of the models are dependent on the positioning and the number of the levels and the specific characteristics of each model, but levels defined near to the true requirement and not so spaced are better to estimate the OL.


O objetivo deste trabalho foi avaliar a influência do número e posição de níveis nutricionais utilizados em ensaios dose-resposta na estimativa do nível-ótimo (OL) e ajuste dos modelos polinomial quadrático (QP), exponencial (EXP), linear response plateau (LRP) e quadratic respose plateau (QRP). Utilizaram-se dados provenientes de ensaios dose-resposta realizados na FCAV-Unesp Jaboticabal, atendendo as pressuposições de homocedasticidade e normalidade. O ajuste dos modelos foi avaliado considerando as seguintes estatísticas: coeficiente de determinação ajustado (R²adj), coeficiente de variação (CV) e soma dos quadrados dos desvios (SSD).Verificou-se que, nos modelos QP e EXP, pequenas mudanças na localização e distribuição dos níveis ocasionam grandes alterações na estimativa do OL. O modelo LRP foi influenciado pela ausência ou presença do nível intermediário às fases de resposta e estabilização (mudança da reta crescente para platô). O modelo QRP precisou de um número maior de níveis na fase de resposta e o último nível da fase de estabilização para estimar corretamente o platô. Pôde-se concluir que a determinação do OL e o ajuste dos modelos dependem da posição e quantidade de níveis, além das características específicas de cada modelo, mas níveis definidos próximos do verdadeiro requerimento e não muito espaçados são melhores para estimar corretamente o OL.

20.
Rev. colomb. biotecnol ; 15(1): 28-41, ene.-jun. 2013. ilus, tab
Article in Spanish | LILACS | ID: lil-696142

ABSTRACT

El desgaste de los insertos de Polietileno de Ultra-Alto Peso Molecular (UHMWPE pos sus siglas en inglés) continúa afectando la longevidad de las prótesis totales de rodilla (PTR) junto con el aflojamiento aséptico, y ambos constituyen las dos principales causas de falla de las prótesis. Considerando esto, es necesario encontrar soluciones adecuadas para evitar el desgaste excesivo y hasta la ruptura de los insertos de polietileno. En este trabajo se realizó el estudio mediante simulación numérica de una PTR Scorpio II® Stryker®, la cual se retiró por desgaste del inserto de UHMWPE en el Hospital 1° de Octubre del ISSSTE en México. Se utilizaron las hipótesis de Bartel et al. (1995) y Chillag et al. (1991) para la validación del método numérico utilizado, las cuales establecen que el desgaste del polietileno puede reducirse utilizando insertos tibiales de mayor espesor, lo cual disminuye las presiones de contacto. Los análisis se realizaron mediante MEF variando el espesor del inserto de 6, 8, 10, 12 y 14 mm, suponiendo cargas axiales de tipo cuasi-estático en la articulación a cero grados de flexión, para 1.33 veces el peso de un individuo de 75 kg (736 N) empleando el ciclo normalizado de marcha. Los resultados obtenidos muestran similitud con los reportados por Bei et al. (2004) y Deen et al. (2006). Después de validar el método, se desarrolló el modelo de MEF de la PTR y se determinaron las curvas de esfuerzo y de áreas de contacto del inserto de UHMWPE, con lo que se obtuvo información importante para modificar el diseño y obtener una prótesis de geometría conforme en los planos coronal y sagital del inserto femoral y el inserto de polietileno, de acuerdo con el fenotipo mexicano.


Wear of UHMWPE inserts continues affecting the longevity of total knee replacements (TKR) together with septic loosening, and both constitute two main causes of prosthesis failure. It is necessary to find appropriate solutions to avoid excessive wear and failure of polyethylene inserts. In this work a study was carried out by means of numeric simulation of a Scorpio II® Stryker® TKR, which was retired due to wear of UHMWPE in the Hospital 1° de Octubre of ISSSTE in Mexico city. Hypotheses of Bartel et al. (1995) and Chillag et al. (1991) were used, which settle down that wear of polyethylene can decrease using thicker tibial inserts, which can be reduced contact pressures. Analyses of this work was carried out by means of FEM varying insert thickness of 6, 8, 10, 12 and 14 mm, considered quasi-static axial loads actuating on the articulation with zero degrees of flexion and loads equivalent to 1.33 times of bodyweight of a subject of 75 kg (736 N) was considered. Normalized gait cycle was employed and results obtained are similar to those reported by Bei et al. (2004) and Deen et al. (2006). After validating the method, a model of study case of TKR in FEM was developed and the curves of stress and contact areas of UHMWPE were determined, with which important information was obtained to modify the design, as well as to obtain a prosthesis of optimal conformity in both coronal and sagital planes of the femoral and UHMWPE inserts, in agreement with characteristics of the Mexican phenotype.


Subject(s)
Humans , Knee , Numerical Analysis, Computer-Assisted , Prostheses and Implants , Polyethylene , Pressure
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