Clinical and patient reported outcomes of Vitamin E diffused highly cross-linked polyethylene liner versus moderately cross linked polyethylene liner in total hip arthroplasty: A meta-analysis

Introduction@#In the modern era of Medicine, total hip arthroplasty (THA) is found to last longer than ever before due to the fact that there has been improved bearing surfaces and materials available. Despite these modern approaches, failure caused by polyethylene wear, aseptic loosening, instability and mispositioning and even infection could affect THA survival. In the course of addressing anti-wear characteristics of the conventional polyethylene surface various approaches have been made. To date, there are very limited studies done in which polyethylene liner is better.@*General Objective@#To compare the effects of vitamin E diffused highly cross-linked polyethylene liner versus moderately cross-linked polyethylene liner in THA. @*Methodology@#Meta-analysis research design was used in this study. The primary investigators conducted a comprehensive literature search from Medline, Cochrane Library, PubMed, Elsevier, Google Scholar, Embase and ClinicalTrial.gov as electronic database. All randomized controlled trials comparing the effects of vitamin E diffused highly cross-linked polyethylene liner versus moderately cross-linked polyethylene liner in THA were included in the review. @*Conclusions@#The investigation disclosed no statistical significance between moderately cross-linked polyethylene liner and vitamin E diffused highly cross-linked polyethylene liner in terms of migration, head penetration and wear on mediolateral, longitudinal and anteroposterior axes after 2 and 5 years of undergoing THA. Moreover, the data pertaining to patient reported outcomes and clinical outcomes measure also indicated no statistical significance between moderately cross-linked polyethylene liner and vitamin E diffused highly cross-linked polyethylene liner. This indicates that vitamin E diffused highly cross-linked polyethylene liner is comparable with the conventional moderately cross-linked polyethylene liner. Vitamin E-infused highly cross-linked polyethylene ( VEPE) showed an almost similar stability with regard to the wear rates and the component showed similar stability with that of moderately cross-linked polyethylene liner.

A retrospective study on the application of cemented polyethylene liner technique in hip revision / 中国修复重建外科杂志

Objective: To evaluate the effectiveness of cemented polyethylene liner technique in hip revision. Methods: Based on inclusion criteria, the clinical data of 26 patients who were undergone hip revision between January 2011 and December 2013, were retrospectively reviewed. Among them, 14 cases were treated with isolated liner exchange (group A) and 12 cases were treated with cemented polyethylene liner technique (group B). There was no significant difference in gender, age, the time from primary total hip arthroplasty to revision, and the preoperative Harris score between 2 groups ( P>0.05). The post-operative Harris score and complications were compared between 2 groups, and X-ray findings of the hip joint were recorded to review the position of hip components. Results: All patients were followed up 4.4-6.4 years (mean, 5.4 years). Except for two femoral fractures during the revision (1 in each group), there was no other complication in 2 groups. The hip pain relieved and the lame gait corrected in 2 groups. The hip's function of 2 groups improved gradually after operation, with a better Harris score at 3 months and the best at the last follow-up, compared with preoperative scores ( P0.05). X-ray films showed no dislocation, aseptic loosening, and other interface related complication. Conclusion: For the cases without the chance to do change liner, cemented polyethylene liner technique has a good effectiveness. But restrict patient selection should be considered before hip revision.

Cementless Total Hip Arthroplasty Using Ceramic Femoral Head on Cross-Linked Ultra-High-Molecular Weight Polyethylene Liner in Patients Older than 65 Years: Minimum Five-Year Follow-Up Results / 대한정형외과학회잡지

PURPOSE: To evaluate the utility of ceramic-on-polyethylene articular bearing surface when cementless total hip arthroplasty is performed in patients older than 65 years through an analysis of the minimum five-year follow-up results using the ceramic femoral head and cross-linked polyethylene liner. MATERIALS AND METHODS: From March 2010 to September 2012, 51 patients (56 hips) who were older than 65 years were enrolled in this retrospective study. The mean age at surgery was 70.9±5.1 years old. A clinical assessment was analyzed using the Harris hip score. For the radiographic assessment, the cup inclination and anteversion, stem alignment, and wear amount were measured. The postoperative complications were also determined. RESULTS: The mean Harris hip score was improved from preoperative 48 points to postoperative 87 points (p < 0.05). The mean cup inclination was 40.9°±6.4° and the mean cup anteversion was 20.3°±8.1°. The mean cup anteversion of the elevated liner-used group (16 cases) was 14.3°±7.9° and the mean cup anteversion of the neutral liner used group (40 cases) was 22.4°±9.1° (p < 0.05). The mean stem alignment angle was 0° (range, varus 4°–valgus 4°). The mean linear wear amount was 0.458±0.041 mm and the average annual linear wear rate was 0.079±0.032 mm/yr. Six cases (10.7%) of intraoperative periprosthetic femoral fractures were encountered. CONCLUSION: Based on these results, the use of a ceramic-on-polyethylene articular bearing surface in elderly patients with cementless total hip arthroplasty is beneficial. On the other hand, careful effort is needed to prevent intraoperative periprosthetic femoral fractures.

Isolated Polyethylene Liner Exchange in a Revision Total Hip Arthroplasty

PURPOSE: To analyze the results of isolated exchange of polyethylene (PE) liners for treatment of wear and osteolysis around a well-fixed Harris-Galante (HG) cementless acetabular cup. MATERIALS AND METHODS: Thirty-three PE liner changes were performed without the removal of stably ingrown implants (33 hips of 32 patients). They were able to be followed for a mean period of 92 months. Clinically, the Harris hip score (HHS), pain evaluation, and complications were evaluated. Radiologically, the annual wear rate and the size of the osteolytic lesions were measured before the operation and the latest follow-up. The bone graft incorporation scale and the development of new osleolytic lesions were checked during the final follow-up. RESULTS: HHS improved to 89.3 at last follow-up. The size of the osteolysis was significantly reduced postoperatively. Bone graft incorporation scales were Grade I in 9 and Grade II in 14 cases. New osteolytic lesions have not developed at latest follow-up. As a complication, one case of dissociation of a liner and a periprosthetic fracture were noted. Annual wear rates during the same period were significantly reduced. There was no sign of alteration in stability of the PE liner. CONCLUSION: Exchange of a PE liner without removal of stable implants can be a good option for the treatment of wear and osteolysis around a stable cementless THA implant, even if the system has a weak locking mechanism, such as the HG cup. In these cases, under certain states with a higher risk of early failure in the locking mechanism, it would be better to select other revision procedures such as cup revision or cemented polyethylene liner fixation.

Short Term Results of Cementation of a Polyethylene Liner into a Well-Fixed Metal Shell

PURPOSE: To evaluate the radiological and clinical results of cementation of a polyethylene liner into a well-fixed metal shell in revision total hip arthroplasty. MATERIALS AND METHODS: From November 2001 to April 2006, 11 cases (10 patients) were included in this study. There were 5 males (6 cases) and 5 females with a mean age of 54.3 years. The mean follow-up period was 35.2 months. The acetabular shells were stable and their position was acceptable in all cases. Pre-existing screws were removed and screw holes were filled with allogenic bone. The inner surface of the metal shells and convex backside of the liners were roughened with a burr. The clinical results were evaluated using the Harris hip score (HHS) and the radiological results with evidence of a positional change in the acetabular cup and liner, and the progression of osteolysis around the cup. RESULTS: The mean HHS was 69.5 points preoperatively and 89.2 at the last follow up. There was no change in the cup and liner position or progression of the osteolytic lesion around the femoral or acetabular components. CONCLUSION: Cementation of a polyethylene liner into a well-fixed metal shell showed satisfactory results in revisional total hip arthroplasty with a short term follow-up period.

The analysis of Affecting Factors for the Dissociation of the Polyethylene Liner in Cementless Harris-Galante Acetabular Component

PURPOSE: This study was performed to evaluate the factors associated with dissociation of the polyethylene liner with using a Harris-Galante I or II acetabular component in a stably positioned acetabular cup. MATERIALS AND METHODS: Between January 1998 and February 2007, 32 cases underwent revision of the acetabular component due to osteolysis, wear of the polyethylene liner or locking mechanism failure around the acetabulum in spite of stable positioning. 5 cases were primarily operated on using the type I Harris-Galante Hip Prosthesis and 27 cases used the type II. We divided the 32 cases into the two groups: Group I (18 cases) was composed of cases with the existence of polyethylene liner (PE) dissociation and Group II (14 cases) had no dissociation. The analyzed factors were age, gender, body weight, the type and the size of the acetabular cup, the thickness of the polyethylene liner, the duration of the time interval from the primary surgery, the inclination and ante-version of the acetabular cup, the wear rate of the PE liner, the degree of the osteolysis around the acetabulum and the existence of failure of the locking mechanism in the acetabular component. Statistical analysis was performed using the Mann-Whitney test (SPSS 12.0). RESULTS: Statistical significance was noted only for the wear rate of the PE liner (Group I: 0.40+/-0.19 mm/year, Group II: 0.19+/-0.08 mm, p=0.002) and the existence of failure of the locking mechanism (Group I: 16 cases (88.9%), Group II: 6 cases (42.9%), p=0.006). CONCLUSION: According to this study, the dissociation of the PE liner was influenced by the wear rate of the PE liner and the existence of failure of the locking mechanism in the acetabular component. In order to prevent PE liner dissociation, improvement of the locking mechanism and the PE liner system are essential.

Total Knee Arthroplasty with Rotating Platform Low Contact Stress(R): Minimum 3-Year Follow-up Results / 대한정형외과학회잡지

PURPOSE: To retrospectively evaluate the clinical and radiology results of total knee arthroplasty using a rotating platform Low Contact Stress (LCS(R)) Complete(TM). MATERIALS AND METHODS: Of 63 patients (82 knees) who had undergone a total knee arthroplasty with a rotating platform LCS(R) Complete(TM) between Jan. 2001 and Dec. 2002, 61 patients (79 knees) were followed up for more than three years and evaluated retrospectively. The average follow-up period was 3.5 years and the diagnosis in all cases was degenerative osteoarthritis. The average age at the time of surgery was 67.4 years, and no patient underwent patella resurfacing. RESULTS: The average active range of motion increased from 118degrees (95degrees-134degrees) preoperatively to 123degrees (100degrees-140degrees) at the last follow up. The average flexion contracture improved from 15degrees (0degrees-30degrees) preoperatively to 2degrees (0degrees-10degrees) at the last follow up. The average HSS knee score also improved from preoperative 64 points to 90 points at the last follow up. The radiology evaluation revealed a radiolucency rate of 10% in the tibia anteroposterior view and 9% in the femur. The complications encountered were two cases of a polyethylene liner dislocation; one in whom an open reduction was performed, and the other in whom the liner had been exchanged. CONCLUSION: A follow-up of the rotating platform LCS(R) Complete(TM) of more than three years yielded overall satisfactory results in the range of motion and function. However, there should be some concern regarding the development of polyethylene liner dislocation.

Treatment of Pelvic Osteolysis with a stable Cementless Acetabular Cup with Exchange of Polyethlene Liner and Morselized Bone Graft

Purpose: We evaluated, retrospectively, twenty hips that had undergone revision surgeries because of massive pelvic osteolysis in order to determine the retention rate of acetabular metal shells and polyethylene liner exchanges.. Materials and Methods: We performed liner exchanges for massive osteolysis around stable HG acetabular cups with severe polyethylene wear in twenty-three hips, between June 1996 and May 2003. Clinical and radiological follow-up was available for 20 hips for more than 2 years. In 18 hips, we performed curettage of the granulomatous tissue and tightly packed morselized cancellous allografts into the screw holes or the peripheral rims for the acetabular osteolytic lesions. The mean follow-up period was 3.8 years (range, 2.4 to 9.3 years) and the mean of time from the primary total hip arthroplasties to the component exchanges, was 8.2 years (range, 5.6 to 12.4 years). Results: During the follow-up period, all of the hips were functioning well, and none required any subsequent repeat surgeries. Dislocations occurred three times after the repeat operations in one hip, which was treated successfully with an abduction brace. None of the hips demonstrated a progression of the pre-existing osteolytic lesions or the development of any new osteolytic lesions. At the final follow-up, none of the acetabular components demonstrated any evidence of loosening. Conclusion: Our results demonstrated that isolated liner exchanges and debridement of the granulomatous tissue, with or without bone grafting, can be an effective alternative solution to revision of the cup for massive osteolysis around well-fixed, cementless, acetabular cups in selected patients. Retention of the pre-existing cementless acetabular cup provides less intra-operative and post-operative morbidity. However, in order to determine the longevity of the retained cementless acetabular cups, further long-term studies are necessary.

Hemiarthroplasty performed with Ultrahigh Molecular Weight Polyethylene Liner Composite in a 10 Years Old Child having Osteosarcoma of the Proximal Tibia: A Case Report / 대한정형외과학회잡지

The proximal tibia is the second most common site for primary malignant bone tumors. With the progression of chemotherapy and surgical technique, limb salvage is being accepted as a generalized procedure, even in growing child. But for those children, especially around 10 years, who still have a considerable growth potential, it is difficult to selecting the appropriate prosthesis, except for cases with arthrodesis, and arthroplasty is an unreasonable procedure in many cases. We tried to maintain the mobile joint along with minimal complications, and we designed the hemiarthroplastic technique using the ultrahigh molecular weight polyethylene (UHMWPE) liner, intramedullary nail, bone cement and low heat treated autograft composite. This article present the results of 52 months follow up on this surgical procedure.

Failure Mode of Polyethylene Liner in Total Hip Arthroplasty with Harris-Galante II Acetabular Cup / 대한정형외과학회잡지

PURPOSE: To assess the mode of a polyethylene liner failure in total hip replacement using a Harris-Galante II acetabular component. MATERIALS AND METHODS: A retrospective review was performed and 128 consecutive primary total hip arthroplasties were analyzed in 111 patients who had a second-generation Harris-Galante cup. All patients were followed up for a minimum of five years, with a mean follow up of 7.4 years (range, 5 to 12.9 years). A total of 26 cups (20.2%) were revised at the time of the latest follow up. The medical records, radiographs, surgical notes, and retrieved components were analyzed in order to determine the precise causes of the revision. RESULTS: Twenty-two cases (17.3%) were found to have experienced problems with the polyethylene liner. Three types of liner failure were identified; metallosis associated with polyethylene liner wear (14 cases), excessive wear without metallosis necessitating a revision (6 cases), and polyethylene liner dissociation without gross evidence of wear (2 cases). CONCLUSION: This study find that polyethylene liner failure is the main cause of the revision of this component. Early surgical intervention needs to be performed before fatal metal damage occurs in order to avoid metallosis, and severe bone stock damage in cases of excessive polyethylene wear.

Polyethylene Liner Wear in Harris-Galante Acetabular Cup: Two Dimensional versus Three Dimensional Method / 대한정형외과학회잡지

PURPOSE: The purpose of this study was to compare the two-dimensional with three-dimensional radiographic measurements of polyethylene liner wear in the Harris-Galante II acetabular cup. MATERIALS AND METHODS: We measured the polyethylene liner wear amount and the wear rate of 64 hips with Harris-Galante II acetabular cup by two methods: Livermore's method and modified Devane's method. We evaluated the relationships between the two methods. RESULTS: The average total amount of wear and the average wear rate are 0.86+/-1.01 mm and 0.18+/-0.20 mm/year using the two-dimensional method and 0.99+/-1.01 mm and 0.21+/-0.2 mm/year using three-dimensional method respectively. The amount of wear and the wear rate by the three-dimensional method was larger than those by the two dimensional method. CONCLUSION: The amount of polyethylene liner wear can be measured by the two-dimensional method because it is highly correlated with the amount that is measured by the three-dimensional method, since there was no differences between the two methods.

Comparison Between Standard and elevated-rim Acetabular Liner in Total Hip Arthroplasty / 대한정형외과학회잡지

PURPOSE: Elevated-rim acetabular liner enhances stability in total hip arthroplasty and has been widely accepted. But it has potential adverse effects. So, we assessed the effects of the elevated-rim acetabular liner clinically and radiologically. MATERIALS AND METHODS: We reviewed the results of 74 total hip arthroplasties of 64 patients that had been performed from January 1993 to March 1995. Thirty-six cases of the 74 cases used elevated rim acetabular liner and 38 cases did standard liner. Dislocation rate, Harris hips score, osteolysis and revision rate were compared between two groups. RESULTS: There were no significant differences in mean anteversion, abduction angles of the cup and femoral offsets between two groups. Four of the 38 cases with the standard liner had a dislocation, compared with one of 36 cases with the elevated-rim liner (P=0.358) . Femoral osteolysis was observed 7 cases (18.4%) in the standard liner group and 14 cases (38.8%) in the elevated-rim liner group. Acetabular osteolysis was observed 17 cases (44.7%) in the standard group and 21 cases (58.3%) in the elevated-rim group. Nine cases (23.6%) had been revised in the standard group and 6 cases (16.6%) in the elevated group. CONCLUSION: Excessive wear and breakage of the polyethylene by impingement was developed in the elevated-rim polyethylene liner.

A Study for The Conformity Between Polyethylene Liner and Metal Backing Cup in THR / 대한정형외과연구학회지

Wear of polyethylene liner and osteolysis appear to be topical problems after long-term follow-up in total hip arthroplasty(THA). Age and activity of patients, manufacturing procedure of polyethylene liner, thickness of the liner, position of acetabular cup, and material of artificial femoral head have of effects on the degree of wear. In addition, conformity, congruency and micromotion between liner and metal cup are likely to be related to the wear. The purpose of this study is 1) to determine the stress caused by contact between metal and polyethylene components, 2) to evaluate the effects of conformity, congruency, and fixation between metal and polyethylene components, on contact stress in acetabular cups and 3) to identify the design parameters of the commercial acetabular cup within the constraints imposed by the overall functional requirements of total joint replacement. The specimens applied to six different commercial cups made in five companies. The methods was performed on dynamic test and static test to rely on load conditions, estimated the gap between the components through LM. The results showed H-G II cup had the most excellent congruency because of the narrowest interval between two components.

Dissociation of Polyethylene liner in Metal backed Cup without Hip Dislocation History: A Case Report / 대한정형외과학회잡지

In 1971, Harris introduced a metal backed acetabular cup to allow replacement of worn polyethylene cups and it has been popularly used now. In metal backed acetabular cup, dissociation between metal shell and polyethylene liner usually occurs with hip dislocation. We report a case of dissociation of polyethylene liner in metal bacded cup not associated with hip dislocation.

Disassembly of Polyethylene Liner in Cementless Metal-Backed Cup: A case report / 대한정형외과학회잡지

In 1971, for purpose of reduction of peak stress occuring in cement and trabecular bone of the acetabulum, Harris reported a series of metal-backed acetabular components with removable polyethylene liners that could be replaced if excessive wear occured. Modular designs of hip prostheses have become popular recently, but they introduce the risk of disassembly of the components postoperatively. And introduce of loosening and infection of femoral or acetabular components by debris of polyethylene liner. We report a case of mechanical disassembly of polyethylene liner in cementless metal backed cup, and review previously reported articles.

A Failure of the Locking System of the Acetabular Assembly in a Total Hip Replacement

In this study, the author presents the case of one patient who had a Harris-Galante total hip replacement for pigmented villonodular synovitis of the left hip joint, the locking system failed and separation of the polyethylene liner from the acetabular metal shell occurred while the closed reduction of the posterior dislocation of the femoral prosthesis was performed. This study indicates that the design of the acetabular assembly should be modified. The gap between the rims of metal shell and polyethylene liner should be reduced or eliminated.