ABSTRACT
PURPOSE: To identify the clinical manifestations and risk factors for poor visual outcome, as well as antibiotic susceptibility of isolates in bacterial keratitis. METHODS: A total of 128 eyes in 128 patients with bacterial keratitis, who were diagnosed by smears and cultures from January 2000 to December 2007 were reviewed retrospectively. Sex, age, previous ocular disease, trauma history, pre-treatment duration, previous ocular surgery, clinical manifestation, causative bacteria, pre- and post-treatment visual acuity, and treatment results were evaluated. An initial univariate and multivariate logistic regression analysis was performed to identify and select the main prognostic factors. The antibiotic susceptibility was evaluated in 2 consecutive 4-year periods. RESULTS: The mean age of the 128 patients was 59.0+/-18.2 years; 67 (52.3%) patients were male. The most common risk factor was ocular trauma (40.6%). The most prevalent isolate was coagulase-negative Staphylococcus (43.7%). Large size (p 0.05). Among the fluoroquinolone antibiotics, susceptibility of ciprofloxacin was 75.7%. CONCLUSIONS: In patients with bacterial keratitis, a large ulcer size and the presence of previous ocular disease were risk factors for poor visual outcome. Gentamicin, cefazolin, and ciprofloxacin should be avoided as primary monotherapy for bacterial keratitis.
Subject(s)
Humans , Male , Anti-Bacterial Agents , Bacteria , Cefazolin , Ciprofloxacin , Eye , Gentamicins , Keratitis , Logistic Models , Retrospective Studies , Risk Factors , Staphylococcus , Ulcer , Visual AcuityABSTRACT
Fifty-two eyes with vitreous hemorrhages caused by branch retinal vein occulusion underwent pars plana vitrectomy. The vIsion was improved postoperatively in 50 of 52 eyes(96.2%) and no change or worsened in 2 eyes. Regarding postoperative visual acuity 73% showed 0.1 or better, and 0.5 or better in 25%. The lens opacity, the most common surgical complication occured in 14 of 43 phakic eyes, and the incidence of later lens opacification increased as the follow-up lengthened. Other surgical complications were retinal tear in 2 eyes, recurrent vitreous hemorrhage in 3 eyes and secondary glaucoma in 2 eyes. Thirty-two eyes revealed postoperative visual acuity less than 0.3, in which 20 eyes showed maculopathy as the cause of poor visual outcome, and surgical complications in 16 eyes. The level of vision depends lagely upon the macular function.