ABSTRACT
Background:Tuberculosis (TB) is a major public health problem. Pulmonary TB sequelae can affect a person's physical and functional capacity leading to decreased quality of life and societal participation. The study aims at evaluating exercise capacity, quality of life, and social participation in patients with post-pulmonary tuberculosis. Material And Methods:An analytical cross-sectional study was carried out in 100 post-tuberculosis patients by convenient sampling. Quality of life was assessed using WHOQOL BREF and social participation was evaluated with the Impact on Participation and Autonomy Questionnaire (IPAQ). Exercise capacity was measured using a six-minute walk test (6MWT). Result:The mean 6MWT distance in males was 333.76 ± 47.10 meters and in females was 335.04 ± 52.34 meters. The mean VO2 peak in males and females was 13.32 ± 2.37 ml/kg/min and 14.02 ± 2.84 ml/kg/min respectively. The quality of life and social participation in both males and females was good. There was a very weak positive correlation between 6MWT and WHOQOL BREF (spearman's rho=0.251) and a moderate negative correlation between WHOQOL BREF and IPAQ (spearman's rho= -0.663) There was no relationship between 6MWT and IPAQ score. Conclusion:The study concludes that the majority of the patients post pulmonary tuberculosis hasfair effort tolerance and good quality of life. It also concludes that there is no statistically significant difference in the quality of life and social participation between males and females.
ABSTRACT
Background: Fungal colonisation of airways in Post TB patients, can lead to a spectrum of diseases based on the immune response of the host. This study was aimed at studying the different entities of this spectrum. Methods: A cross sectional observational study was conducted over 100 patients of post TB patients to make an observation of the diseases of the spectrum of Aspergillus infections. Results: Of the 100 patients who were studied, IPA was found in 24 (48%), ABPA in 13(26%), CPA in 5(10%) patients out of the 50 diabetics. ABPA in 23 (46%) patients, Simple colonization, CPA in 11(22%) and 4 (8%) patients showed IPA out of the 50 non-diabetics. Conclusion: Chronic pulmonary Aspergillosis was the most common disease from Aspergillus among Post TB patients. Diabetes was associated to invasive forms of Aspergillosis, Invasive Pulmonary aspergillosis (IPA) and subacute invasive pulmonary aspergillosis (SAIA).
ABSTRACT
Background: More than fifty percent of the cured cases of pulmonary tuberculosis develop some form of chronic pulmonary dysfunction. It can present with varying degrees of lung damage, ranging from minimum functional abnormalities to severe forms of dysfunction that can be an important cause of death. Objective of the study to identify the various Post Tuberculosis Lung Diseases (PTBLDs) and to study impact of the patient and disease related factors on its occurrence.Methods: Cross-sectional, observational study was conducted in 134 adult, post tuberculosis patients, aged between 18-65 years, who have completed at least one year after the end of anti-tubercular treatment. All symptomatic post TB lung disease patients coming to the pulmonology out-patient clinic at the Apollo Institute of Medical sciences and Research were included in the study.Results: Majority were more than 50 years (35.3%) and males (59.4%). Majority were from urban areas (70.7%), low social class (72.2%), and unskilled workers (56.4%). Most common symptom was cough in 74.4% cases. Majority of the cases had symptoms from one week to one month i.e. 47.4%. Only eight cases were found out to be very prompt in reporting their symptoms. 39 cases had some or the other co-morbidity. Current chest X-ray status was normal in only three cases. Mean FEV1 was 1.38 which increased to 1.52; mean FVC was 1.23 which increased to 1.58; mean FEV1/FVC was 67.37 which increased to 72.76 after giving the bronchodilator. 78(58.6%) cases had obstructive and 27(20.3%) had restrictive lung disease. In 30 cases the disease was reversible. Majority of the cases were of pulmonary fibrosis followed by bronchiectasis.Conclusion: Further studies are needed to develop approaches for the prevention, care and treatment of patients with post TBLD.