Risk factors for infection after subtotal gastrectomy in patients with gastric cancer / 中国感染控制杂志

Objective To explore risk factors for infection after subtotal gastrectomy in patients with gastric cancer, and provide reference for prevention of infection.Methods Clinical data of gastric cancer patients who were admitted to a hospital from July 2010 to June 2014 for subtotal gastrectomy were analyzed retrospectively, related factors for post-operative infection were explored.Results A total of 210 gastric cancer patients who underwent subtotal gastrectomy were enrolled, 36 patients had healthcare-associated infection (HAI) after operation, incidence of HAI was 17.14％, the main HAI were abdominal infection (n=10) and surgical site infection (n=9).Univariate analysis showed that incidence of post-operative infection was higher in gastric cancer patients who were older than 55 years, malnutrition, laparotomy, tumor-nodes-metastasis (TNM) stageⅢ-Ⅳ, and bedridden time＞4 days after operation (all P＜0.05).Logistic regression analysis showed that patients' age＞55, malnutrition, and laparotomy were independent risk factors for infection after subtotal gastrectomy (all P＜0.05).Conclusion Old age, poor nutritional status, and laparotomy are risk factors for infection after subtotal gastrectomy in patients with gastric cancer, effective prevention and control measures should be formulated according to these factors before and after operation.

Vancomycin-Loaded Bone Cement Bullet for Treatment of Chronic Septic Arthritis Post ACL Reconstruction Surgery

Abstract@#The consequence of post-operative infection can be devastating despite its rare incidence. Common organisms causing post-operative infection are normal flora of the skin: Staphylococcus aureus and Staphylococcus epidermidis. Early diagnosis followed by arthroscopic debridement and antibiotic therapy with graft retention remains the main aim of treatment. However, there are certain cases where the infection persists despite early intervention. Vancomycin-loaded bone cement bullet inserted into bone tunnel can provide a high local concentration of vancomycin with bactericidal effect and low systemic complications to treat deep-seated infection.

Comparative evaluation of short-term versus long-term post-operative antibiotic prophylaxis after mandibular fractures.

Background: No consensus is present among the clinicians regarding the use of post-operative antibiotics after the open reduction and internal fixation. This study evaluates the efficacy of short-term (48 hrs) versus long-term (5 days) post-operative antibiotics in preventing infection rates after the open reduction and internal fixation in mandible fractures. Methods: A total of 80 patients of dentate mandibular fractures were divided randomly in 2 groups; Group 1 received post-operative intravenous antibiotics (amoxicillin+clavulanate 1.2 g+ metronidazole 0.5 g/100 cc) TDS for 48 hrs postoperatively Group 2 received same course for 5 post-operative days and patient were monitored for the signs of infection according to the centers for disease control and prevention criteria, rise in white blood cells counts and C-reactive protein (CRP) levels. Side effects were recorded in both groups. Results: Out of 39 patients in Group 1 two patients showed rise in CRP levels and single patient developed abscess, whereas in Group 2 wound dehiscence was noted in 2 patients and both had prolonged rise in CRP levels at the 5th day. Conclusions: No significant difference in post-operative infection rates was seen between two groups which suggests short-term post-operative antibiotic treatment is equally efficacious as long-term treatment.

A Case of Post-Operative Intra-Abdominal Infection Caused by Corynebacterium Striatum / 대한내과학회지

Corynebacterium striatum is an aerobic, Gram-positive bacillus that is part of the resident flora of skin and mucosal membranes. C. striatum is usually considered a non-pathogenic contaminant, although infective endocarditis and respiratory infection, and less frequently arthritis and meningitis, due to C. striatum have been reported. C. striatum has been particularly associated with catheter-related infections and infections following conditions that resulted in disruption of the skin barrier in both immunocompromised and immunocompetent hosts. We describe a case of post-operative intra-abdominal infection caused by the rare pathogen, C. striatum.

A Case of Post-Operative Intra-Abdominal Infection Caused by Corynebacterium Striatum / 대한내과학회지

Corynebacterium striatum is an aerobic, Gram-positive bacillus that is part of the resident flora of skin and mucosal membranes. C. striatum is usually considered a non-pathogenic contaminant, although infective endocarditis and respiratory infection, and less frequently arthritis and meningitis, due to C. striatum have been reported. C. striatum has been particularly associated with catheter-related infections and infections following conditions that resulted in disruption of the skin barrier in both immunocompromised and immunocompetent hosts. We describe a case of post-operative intra-abdominal infection caused by the rare pathogen, C. striatum.

The influence of mandibular third molar on mandibular angle fracture

0.05). In the extracted or non extracted of mandibular third molar, the post operative infection showed no statistical significant difference(P>0.05). With the results mentioned above, mandibular third molar was significantly more susceptible to mandibular angle fracture. In the reduction of mandibular angle fracture, it was recommended that mandibular third molar should be extracted especially in case of pericoronitis, periodontitis and other infections.

Post-operative Infections and Microbiology in Patients who Underwent Damage Control Laparotomy with Abdominal Packing / 中华医院感染学杂志

OBJECTIVE To determine the prevalence of post-operative infections in patients who underwent damage control laparotomy(DCL) with abdominal packing and to identify the risk factors,mortality and predominant pathogens.METHODS A retrospective study of postoperative infections and microbiology in patients who underwent abdominal packing as an adjunct of DCL to control coagulopathic hemorrhage over a 5 year period(Feb 2002-Feb 2007) were performed.RESULTS A total of 26 patients were studied.Pneumonia/lower respivatory tract infection was the prominant type of infection(57.7%),followed by bacteremia(50.0%),urinary tract infection(15.4%) and wound infection(15.4%).Of the 244 organisms isolated from various sites,the most frequently isolated bacteria were Pseudomonas aeruginosa(27.0%),Staphylococcus species(15.6%),Acinetobacter baumannii(13.9%),and Klebsiella species(11.1%).No statistical correlation was found between positive packs and postoperative infection(P=0.10) or death(P=1.00).Multivariate regression analysis revealed that pre-existing abdominal infection(OR=22.4,P=0.02) and increased number of surgical procedures(OR=3.69,P=0.05) were the independent risk factors for post-operative infections.CONCLUSIONS Patients who undergo DCL with packing have a high incidence of postoperative infections.Pathogens and distribution are same as acquired infections.Pre-existing abdominal infection and increased number of surgical procedures are the independent risk factors for postoperative infections in these patients.