ABSTRACT
PURPOSE: The aim of this study was to characterize the changes in the incidence and clinical characteristics of nonoliguric hyperkalemia (NOHK), together with plasma potassium levels, according to the fluid therapy strategies for extremely low birth weight infants (ELBWIs) during the first few days of life. METHODS: This retrospective study enrolled ELBWIs. We analyzed the occurrence of NOHK, plasma potassium levels, other biochemical data, and fluid balances according to historically controlled strategies such as conventional limited-volume supply and low-dose calcium supplementation (P1), increased-volume supply and high-dose calcium supplementation (P2), and early aggressive nutrition (EAN) and high-dose calcium supplementation (P3). RESULTS: The incidence of NOHK and the plasma potassium levels in P2 (127 ELBWIs) were not different from those in P1 (39 ELBWIs). However, arrhythmia and fatality significantly decreased in P2 compared to those in P1. In P3 (68 ELBWIs), the incidence of NOHK after 24 h and the plasma potassium levels after 36 h of life were significantly reduced compared to those in P1 and P2. Neither arrhythmia nor fatality developed in P3. CONCLUSION: EAN combined with high-dose calcium supplementation could be a potential strategy for the prevention of NOHK along with consequent arrhythmia and fatality in ELBWIs.
Subject(s)
Humans , Infant , Infant, Newborn , Amino Acids , Arrhythmias, Cardiac , Calcium , Fluid Therapy , Hyperkalemia , Incidence , Infant, Low Birth Weight , Nitrogen , Plasma , Potassium , Retrospective StudiesABSTRACT
The sera of ninety-one normal Filipino students from 17 to 24 years old were analyzed for sodium and those of eighty-five for potassium by flame photometry employing the internal standard method. The actual ranges, the ranges of 95% of the cases, their averages and standard deviations are presented. The frequency distribution of the cases is given for both serum sodium and serum potassium valuesThe precautions in the preparation of glassware used in the sampling and analysis of sera, those to be observed when obtaining the samples and the internal standard method of flame photometry for the determination of serum sodium and potassium are described. (Summary)