Pyoderma Gangrenosum of the Preauricular Area with Ulcerative Colitis: A Case Report and Review

Pyoderma gangrenosum (PG) is primarily, a sterile, inflammatory, neutrophilic dermatosis, characterized by recurrent cutaneous ulceration with mucopurulent or hemorrhagic exudate. The incidence of PG is uncertain, but it is estimated to be about 3-10 patients per million per year. It occurs most commonly on the lower legs, but has been reported at other sites of the body as well. The causes of PG are unknown, but about 50-70% of cases are associated with other diseases, mainly inflammatory bowel disease. We hereby report a case of PG in a 21-year-old male, with a history of ulcerative colitis (UC). After appropriate diagnostic methods including biopsy for pathologic confirmation, sigmoidoscopy and computed tomography, we excluded other diseases and the lesion was diagnosed as PG. We then carried out regular dressing of the wound, while UC was treated with steroid and immunosuppressant medication, with inputs from the department of gastroenterology during the hospital stay. There occurred recurrence of the skin lesion, 7 months after discharge, after which they improved. UC has been in the remission state as per the follow-up, since 2 years.

A Case of Verrucous Carcinoma Occurring on the Preauricular Region / 대한피부과학회지

Verrucous carcinoma is a relatively non-aggressive, slowly growing, low grade squamous cell carcinoma with little tendency to metastasize. It typically occurs on the oropharynx, genitalia and palmoplantar areas. Until now, there have been several case reports of this tumor occurring on the oral cavity, penile area, sole and lower leg in Korean literature. However, its occurrence on the preauricular area is extremely rare. Herein we report a case of verrucous carcinoma developed on the right preauricular region in a 67-year-old man.

An Ectopic Pleomorphic Adenoma in the Superficial Subcutaneous Layer of the Preauricular Area

Pleomorphic adenoma is a benign tumor originated from the mature salivary tissue. Ectopic pleomorphic adenoma is defined as an unusual presentation of pleomphic adenoma in other sites except the major salivary gland and the minor salivary gland. Ectopic pleomorphic adenoma was found in the soft tissue of the neck, in the skin of the external auditory canal, in the subcutaneous layer of the nose, and in the lymph node of the mediastinum. Ectopic pleomphic adenoma could appear due to the metastasis, the neoplastic degeneration of the ectopic salivary tissue, or the implantation after the surgery of a salivary gland tumor. We present a case of pleomorphic adenoma found in the superficial subcutaneous layer above the superficial musculoaponeurotic system(SMAS) of the preauricular area. The patient had no history of the surgery of the salivary tumor and no specific physical finding. We discussed the previous cases of ectopic salivary tissues and ectopic pleomorphic adenomas. No case of the ectopic salivary tissue nor ectopic pleomorphic adenoma in the superficial subcutaneous layer of the preauricular area has been reported. This case could be a rare presentation of the ectopic pleomorphic adenoma from the ectopic salivary tissue arising from the division of the parotid gland in early embryonic period.