Prevalência dos indicadores de saúde pré-concepcional das mulheres brasileiras em idade reprodutiva / Prevalence of preconception health indicators among Brazilian women of reproductive age

Resumo O objetivo deste artigo é avaliar o desempenho de indicadores de saúde pré-concepcional das mulheres brasileiras em idade reprodutiva segundo as características sociodemográficas. Estudo epidemiológico e descritivo com dados de 21.645 e 25.228 mulheres que responderam à Pesquisa Nacional de Saúde de 2013 e 2019 e provenientes do DATASUS de 2010 a 2020. Estimou-se a prevalência de indicadores, segundo características sociodemográficas, e as diferenças estatísticas por meio do teste qui-quadrado de Pearson. Calculou-se a taxa de incidência dos indicadores de sífilis e HIV. Houve aumento da prevalência de indicadores que se referem ao acesso aos serviços de saúde (consultas médica, odontológica e realização de Papanicolau recente). Contudo, houve aumento da hipertensão, do consumo de álcool e da obesidade. Observou-se manutenção da prevalência do uso de contraceptivo e tratamento de fertilidade. Além disso, a taxa de incidência da sífilis aumentou sete vezes entre 2010-2020. Os resultados foram ainda piores entre mulheres de baixa escolaridade, pretas/pardas, com maior paridade e do Norte/Nordeste. Apesar do aumento no acesso aos serviços de saúde, houve piora do desempenho de indicadores de saúde pré-concepcional, e manutenção das iniquidades em saúde.

Abstract This article aims to evaluate the performance of preconception health indicators according to sociodemographic characteristics among Brazilian women of reproductive age. We conducted a descriptive epidemiological study using data from 21,645 and 25,228 women, respectively, who responded the 2013 and 2019 national health surveys, and data for the period 2010 to 2020 derived from the national health system's Department of Informatics (DATASUS). We calculated the prevalence of indicators according to sociodemographic characteristics and statistical significance of differences was measured using Pearson's chi-squared test. Syphilis and HIV incidence rates were also calculated. There was an increase in the prevalence of access to health service indicators (medical and dental consultations and recent Pap smear). However, there was an increase in the prevalence of hypertension, alcohol use, and obesity. The prevalence of use of contraceptive methods and fertility treatment remained stable. Syphilis incidence increased sevenfold between 2010 and 2020. Black/brown women with a low level of education, higher parity, and living in the North or Northeast performed worse for preconception health indicators. Despite the increase in access to health services, performance on preconception health indicators declined and health inequities continued.

Intervención educativa en estudiantes de Enfermería sobre epigenética y prevención preconcepcional de enfermedades crónicas

Introducción: la prevención de las enfermedades crónicas no trasmisibles de elevada prevalencia a nivel mundial, representa una prioridad en salud; en este sentido, la epigenética aporta una nueva perspectiva a la prevención de las mismas. Objetivo: evaluar la efectividad de una intervención educativa en estudiantes de la Licenciatura en Enfermería de la Universidad de Ciencias Médicas de Matanzas, a fin de incrementar el nivel de conocimientos en epigenética y prevención preconcepcional de enfermedades crónicas, realizada entre abril y julio de 2022. Materiales y métodos: se realizó un estudio de intervención que constó de tres etapas, en un universo de 54 estudiantes de primer y tercer años del curso regular diurno de la Licenciatura en Enfermería. Se empleó una encuesta para medir los conocimientos de los mismos en epigenética y prevención preconcepcional de enfermedades crónicas. Resultados: el nivel de conocimientos en epigenética y prevención preconcepcional de enfermedades crónicas previo a la intervención, fue calificado de malo. Conclusión: después de la implementación del programa educativo, se elevaron los conocimientos sobre epigenética y prevención preconcepcional de enfermedades crónicas en estudiantes de Licenciatura en Enfermería, demostrándose así su efectividad.

Introduction: the prevention of chronic non-preventable diseases of high-prevalence worldwide represents a health priority; in this sense, epigenetics brings a new perspective to their prevention. Objective: to assess the effectiveness of an educative intervention carried out between April and July 2022 in students of the Nursing degree from Matanzas University of Medical Sciences, with the aim of increasing their level of knowledge on epigenetics and preconception prevention of chronic diseases. Materials and methods: a three-stage intervention study was carried out, in a universe of 54 students of first and third years of the regular day-time course of the Nursing degree. A survey was used to measure their knowledge on epigenetics and preconception prevention of chronic diseases. Results: the level of knowledge on epigenetics and preconception prevention of chronic diseases prior to intervention was qualified as bad. Conclusion: after the implementation of the educative program, the knowledge on epigenetics and preconception prevention of chronic diseases increased in students of the Nursing degree, thus demonstrating its effectiveness.

Comparison of the detection rates of preconception health risks among Chinese couples of reproductive age in 2013 and 2019 / 中华健康管理学杂志

Objective:To assess the detection rates of preconception health risks among couples of reproductive age in China and analyze the differences between 2013 and 2019.Methods:In this cross-sectional study, the preconception health examination data of 9 153 916 couples of 20-49 years who participated in the National Free Preconception Health Examination Project in 2013 or 2019 were consecutively selected. The health risks involved eight aspects in women (genetic risk, reproductive risk, chronic disease risk, infectious risk, nutritional risk, behavioral risk, environmental risk and psychosocial risk) and seven aspects in men except for reproductive risks were assessed. The t test and χ2 test were used to compare the differences in demographic characteristics between the couples of reproductive age. The detection rates and 95% CI of each preconception health risk were calculated and the χ2 test was used to compare the differences in the detection rates of risk factors. Results:In 2019, the proportion of couples of reproductive age in China who were 35 years or older, had an education background of high school and above, workers, and held non-agricultural registered residence were all higher than those in 2013 (15.18% vs 6.22%, 52.12% vs 29.78%, 8.33% vs 7.17%, 12.39% vs 6.64%), while the proportion of farmers was significantly lower than that in 2013 (60.95% vs 76.87%) (all P<0.001). In 2013, the three health risks with the highest detection rate among Chinese women of reproductive age was nutritional risk (37.50%), infectious risk (16.95%) and psychosocial risk (11.62%), respectively; while in 2019, it was nutritional risk (38.07%), infectious risk (12.82%), and chronic disease risk (11.12%), respectively. The detection rate of nutritional risk in Chinese women of reproductive age in 2019 was significantly higher than that in 2013 (38.07% vs 37.50%), while the detection rates of infectious risk and psychosocial risk were both lower than those in 2013 (12.82% vs 16.95% and 7.37% vs 11.62%) (all P<0.001). In 2013, the top three risks detected in men of reproductive age was behavioral risk (44.87%), nutritional risk (36.81%) and psychosocial risk (13.43%), respectively; and in 2019, it was nutritional risk (45.47%), behavioral risk (38.76%) and psychosocial risk (9.18%), respectively. The detection rates of nutritional risk in men of reproductive age in 2019 was significantly higher than that in 2013 (45.47% vs 36.81%), while the detection rates of behavioral risk and psychosocial risk were both lower than those in 2013 (38.76% vs 44.87%, 9.18% vs 13.43%) (all P<0.001). Conclusions:The detection rate of nutritional risk in couples of reproductive age and genetic risk in men in 2019 in China are higher than those in 2013, and the exposure to the other preconception health risks is decreasing. The nutritional risk, infection risk, psychosocial risk and chronic disease risk are the main risk factors for women of reproductive age, while the nutritional risk, behavioral risk and psychosocial risk are the main risk factors for men.

Intervención educativa sobre riesgo preconcepcional en mujeres de un Área de salud en Guantánamo / Knowledge intervention on preconception risk in women from a health area in Guantánamo

Fundamento: La salud reproductiva está presente durante el ciclo vital de las mujeres y los hombres; en la que juega un papel decisivo la planificación familiar, el conocimiento y manejo del riesgo reproductivo. Objetivo: Evaluar la efectividad de una intervención educativa, en mujeres de edad fértil con riesgo preconcepcional, pertenecientes al consultorio "La Colonia", del Policlínico "Rafael Teope Fonseca", "El Salvador", Guantánamo, desde septiembre 2017 a abril 2019. Metodología: Se realizó un estudio cuasiexperimental, tipo intervención educativa sobre riesgo preconcepcional, con diseño antes y después. El universo fue de 65 mujeres en edad fértil. Se utilizó muestreo no probabilístico intencional. La muestra fue de 45 mujeres con riesgo preconcepcional. La investigación se realizó en 3 etapas: diagnóstica, intervención y evaluación. La información se recogió en una encuesta semiestructurada que se aplicó antes y después de la intervención. Las variables fueron: métodos para planificar el embarazo, edad óptima para el embarazo, antecedentes obstétricos desfavorables, importancia del consumo de ácido fólico antes del embarazo y conocimiento general sobre el tema. Se determinó el test de McNemar para el análisis estadístico e índice de kappa para determinar efectividad de la intervención. Resultados: Antes de la intervención se diagnosticó nivel de conocimiento inadecuado sobre los métodos para planificar el embarazo (42 %), edad óptima para el embarazo (40 %) y en los antecedentes obstétricos (36 %). Posterior a la intervención el nivel de conocimiento adecuado fue significativo (p<0.05) en todas las variables. El índice kappa arrojó acuerdo considerable. Conclusiones: La intervención educativa fue efectiva.

Background: Reproductive health is present during women and men's life cycle, so family planning, knowledge and management of reproductive risk play a significant role. Objective: To evaluate the effectiveness of a knowledge intervention in fertile age women with preconception risk, at "La Colonia" clinic, in "Rafael Teope Fonseca" Polyclinic, "El Salvador", Guantánamo, from September 2017 to April 2019. Methodology: A quasi-experimental study was conducted, of educational intervention type on preconception risk, with formerly and subsequently designs. The universe was 65 women of fertile age. Intentional non-probabilistic sampling was used. The sample was 45 women with preconception risk. The research was conducted in 3 stages: diagnosis, intervention and evaluation. The information was collected in a semi-structured survey applied before and after the intervention. The variables were: methods for planning pregnancy, optimal age for pregnancy, unfavorable obstetric history, importance of folic acid intake before pregnancy, and general knowledge on the subject. The McNemar test was determined for the statistical analysis and the Kappa index to determine the effectiveness of the intervention. Results: Before the intervention, an inadequate level of knowledge was diagnosed about the methods for planning pregnancy (42 %), the optimal age for pregnancy (40 %) and the obstetric history (36 %). After the intervention, the adequate level of knowledge was significant (p<0.05) in all the variables. The Kappa index showed considerable agreement. Conclusions: The educational intervention was effective.

A Cross-sectional Study on Prevalence and Determinants of Preconception Anemia in Women of Reproductive Age Group at Gandhinagar, Gujarat, India

Introduction : Nutritional anemia is a major public health issue that affects women of all ages, notably those of reproductive age (15-49 years). Anemia has an adverse effect on the outcome of pregnancy including miscarriage, intrauterine growth retardation, low birth weight, post-partum hemorrhages and stillbirth. Objectives: It is to estimate prevalence of anemia and to investigate socio-demographic and obstetric factors associated with the prevalence of anemia during preconception period. Method: We conducted a cross- sectional study among 306 reproductive age group (15-49 years) women who were residing in field practice area of Urban Health Training Center (UHTC) in sector-24, Gandhinagar, Gujarat, India who are planning to conceive within a year. Study participants were selected from the records of the female health worker according to our inclusion and exclusion criteria for the study. Results: Out of 306 participant women, 76% were found to be anemic, out of which, 31% had mild, 55% had moderate and 14% had severe level of anemia. Education level significantly associated (P < 0.05) with presence of anemia as women with lower level of education had higher presence of anemia – 81.97% in primary education group and 79.17% among illiterate women. BMI, parity and family type was also found to be significantly (P < 0.05) associated with the severity of anemia. Conclusion: Nearly three fourth Women who planned to conceive within a year had anemia. Out of women who had anemia, nearly three fourth had moderate to severe anemia. Education had significant association with presence of anemia and low BMI, Parity and type of family had significant association with severity of anemia.

Effects of pre-pregnancy body mass index, gestational weight gain and early feeding behavior on lactogenesis stage Ⅱ: a prospective study / 中华围产医学杂志

Objective:To investigate the influence of pre-pregnancy body mass index (BMI), gestational weight gain and early feeding behavior on delayed onset of lactogenesis stage Ⅱ(DOL Ⅱ).Methods:This was a prospective study involving puerperae from Women's Hospital of Nanjing Medical University from March 2020 to June 2020. Demographic data and delivery data were obtained using questionnaires and breastfeeding behavior and milk secretion were followed up every day after delivery. According to whether the lactation initiation was longer than 72 h or not, all subjects were divided into DOL Ⅱ group or non-DOL Ⅱ group. Differences in general condition and breastfeeding between the two groups were compared using independent sample t-test, Chi-square test, and Mann-Whitney U test. Multivariate logistic regression analysis was used to analyze the risk factors of DOL Ⅱ. Results:During the study period, a total of 390 cases were enrolled and 334 cases among them were analyzed due to lost of follow-up in 56 cases. The incidence of DOL Ⅱ was 19.2% (64/334). Univariate analysis showed that body mass index [lean:18.8% (12/64) vs 13.3% (36/270); fit:56.2% (36/64) vs 74.8% (202/270); overweight: 25.0% (16/64) vs 11.9% (32/270); χ2=9.78], mode of delivery [vaginal delivery: 37.5% (24/64) vs 52.6% (142/270); cesarean section: 62.5% (40/64) vs 47.4% (128/270); χ2=4.71], nipple type score in LATCH score [2.0 (1.0-2.0) vs 2.0 (2.0-2.0), U=－2.08], frequency of breastfeeding in 24 h [(6.3±3.0) vs (8.3±3.6) times per day, t=－3.94], adding formula within 24 h [71.9% (46/64) vs 56.3% (152/270), χ2=5.20] and the proportion of attending breastfeeding clinic during pregnancy [73.4% (47/64) vs 85.6% (231/270), χ2=5.44] were significantly different between the DOL Ⅱ and non-DOL Ⅱ groups (all P<0.05). Multivariate logistic regression analysis showed that pre-pregnancy overweight was an independent risk factor for DOL Ⅱ ( OR=2.240, 95% CI:1.020-4.918, P=0.044), either was pre-pregnancy overweight with appropriate gestational weight gain ( OR=5.595, 95% CI:1.492-20.985, P=0.011), while breastfeeding frequency within 24 h ( OR=0.867, 95% CI: 0.780-0.963, P=0.008) and attending breastfeeding clinic during pregnancy ( OR=0.377, 95% CI: 0.173-0.820, P=0.014) were independent protective factors for DOL Ⅱ. Conclusions:Women who were overweight before pregnancy are more likely to suffer from DOL Ⅱ. Extra guidance should be given to this population during early breastfeeding. Attending prenatal breastfeeding consultation and increasing the frequency of breastfeeding in the early postpartum period may prevent DOL.

Influencing factors of intention to utilize preconception health care services among women with future pregnancy plan / 上海预防医学

ObjectiveTo understand the influencing factors of women’s intention to utilize preconception health care services， so as to promote the utilization of preconception care among women with future pregnancy plan. MethodsThe study was conducted at 8 outpatient health clinics of medical institutions providing perinatal health care in Jiading District of Shanghai. Women who had fertility intention for another child were invited to complete an electronic questionnaire from November 2020 to February 2021. ResultsWomen with better pregnancy and birth care behaviors during the last periconception were more likely to utilize preconception care service before the next conception than those with previous poorer behaviors （OR=1.980， 95%CI= 1.061‒3.694， P=0.032）. Women with higher preconception care knowledge scores had better pregnancy and birth care behaviors during the last periconception than those with lower knowledge scores （OR=1.362， 95%C1= 1.004‒1.846， P=0.047）. ConclusionsIn order to improve the utilization of preconception care among the population with future pregnancy plan， it is necessary to further strengthen health education and social mobilization to promote the preconception eugenic knowledge， planned pregnancy and pregnancy and birth care behaviors.

Do Our Diabetic Patients Ready for Safe Pregnancy? Attitude Towards Preconception Care and Its Associated Factors Among Women With Diabetes Attending Government Health Clinics in Terengganu

@#Introduction: Women with uncontrolled diabetes may conceive but will result in poor pregnancy outcomes. This study aimed to assess the level of knowledge and attitude and determine factors associated with attitude towards preconception care. Method: A cross-sectional study was conducted in various government health clinics from all districts in Terengganu by using multistage random sampling. A self-administered questionnaire was applied to assess the level of knowledge and attitude towards preconception care. Multiple logistic regressions were applied to determine factors associated with attitude towards preconception care. Results: A total of 422 respondents were involved. The prevalence of respondents with unsatisfactory knowledge and attitude were 41.7% and 84.1%, respectively. Knowledge was not significantly associated with attitude. Respondents who used contraception had a better attitude (Adj. OR: 0.44, 95% CI:0.23,0.84). Low household income was associated (Adj. OR: 2.40, 95% CI:1.10,5.26) with an unsatisfactory attitude towards preconception care. Conclusion: Attitude towards preconception care amongst diabetic women who were attending primary care clinics was unsatisfactory. A structured and focused preconception educational programme care is necessary, especially amongst low-income women.

A sexualidade humana: maldição ou mal-entendido? / Human sexuality: curse or misunderstanding?

Resumo Este artigo propõe uma reflexão acerca do pavor que, no Brasil, tem assolado grande parcela da sociedade no que se refere às questões de sexualidade e de gênero, mais especificamente, a crença de que as crianças, consideradas desprovidas de sexualidade, podem ser influenciadas pelo discurso "pervertido" que os militantes e apoiadores do movimento LGBTQI+ estariam tentando propagar. Após uma breve descrição do cenário atual, formulações psicanalíticas são apresentadas, visando a desmitificar a equivocada ideia de "pureza" relacionada à infância e levantar hipóteses que explicariam essa rejeição absoluta a tudo o que foge à norma no campo da sexualidade.

Abstract This article proposes a reflection on the dread that, in Brazil, has plagued a large part of society with regard to issues of sexuality and gender, more specifically, the belief that children, considered to be devoid of sexuality, can be influenced by "perverted" discourse that activists and supporters of the LGBTQI+ movement would be trying to spread. After a brief description of the current scenario, psychoanalytical formulations are presented, aiming to demystify the mistaken idea of "purity" related to childhood and to raise hypotheses that would explain this absolute rejection of everything that is outside the norm in the field of sexuality.

Ciência da disseminação em DOHaD para a promoção da saúde nas futuras gerações / Dissemination Science in DOHaD for health promotion in future generations

Após o reconhecimento de princípios evolutivos e da epigenética associada à plasticidade do desenvolvimento, a ciência de DOHaD (Origens Desenvolvimentistas da Saúde e Doença) floresceu. Segundo DOHaD, a exposição a condições adversas no início da vida, como a subnutrição, leva a respostas adaptativas para aumentar as chances de sobrevivência imediata e posterior, as quais podem aumentar o risco de doenças crônicas não transmissíveis (DCNT) no curso da vida. Outros insultos como obesidade (materna e paterna) na preconcepção e gestação, diabetes gestacional, aleitamento e a alimentação inadequada na infância podem induzir respostas não adaptativas e aumentar o risco de doenças, independentemente do ambiente posterior. A exposição à desreguladores endócrinos, substâncias tóxicas e poluentes também podem ter efeitos de longo prazo. Esses efeitos são mediados por alterações epigenéticas, as quais se tornam mais sensíveis nesse período crítico de desenvolvimento de intensa reorganização. Diante da transição nutricional e coexistência das diferentes formas de desnutrição nos países de baixa e média renda (PBMR); do aumento global das DCNT, cujo impacto social e econômico é maior nesses países; da fraca contribuição de fatores genéticos fixos na etiologia dessas doenças; e da ineficácia das atuais intervenções, a implementação de DOHaD representa uma estratégia potencial para beneficiar as futuras gerações. Considerando que a disseminação de DOHaD não têm acompanhado seu florescimento científico, esse trabalho teve como objetivo o desenvolvimento de um ebook direcionado para nutricionistas e um artigo relativo aos impactos da pandemia de COVID-19 na perspectiva de DOHaD, a fim de aproximar a ciência destes profissionais e fomentar sua implementação. Trata-se de uma revisão narrativa de literatura a partir artigos científicos em inglês e português, publicados nas bases de dados SciELO, PubMed e BVS, sem limite de data. O trabalho evidenciou que o desafio da dupla carga de doenças e das diferentes formas de desnutrição nos PBMR, foi agravado pela pandemia, tornando imperativo medidas de intervenção por seu provável impacto no ciclo intergeracional de DCNT e desenvolvimento dos países. A aproximação dessa ciência do nutricionista, propicia uma formação mais ampla e integrativa, através de capacitação técnica e habilidades interpessoais, capazes de acionar as fragilidades biopsicossociais, e melhor intervir, equacionando resultados de curto e longo prazo, a fim de interromper o ciclo intergeracional de DCNT, assim como otimizar o capital humano, a capacidade de produção e renda da futura geração. Conclui-se que o material desenvolvido é de grande valia, dado que a disseminação desse conhecimento deve se estender aos nutricionistas de todas as áreas e ser multiplicado

After evolutionary and epigenetics principles associated with the plasticity of development were recognized, DOHaD (Developmental Origins of Health and Disease) science flourished. According to DOHaD, the exposure to adverse conditions at the beginning of life, like undernutrition, leads to adaptive responses to increased immediate and later odds of survival, which may increase the risk of noncommunicable diseases (NCD) during life. Other conditions such as obesity (maternal and paternal) in preconception and pregnancy, gestational diabetes, lactation, and inadequate nourishment during infancy can induce non-adaptive responses and increased risk of diseases, regardless of the upcoming environment. The exposure to endocrine disruptors, and toxic and pollutant substances can also have long-term effects. Those effects are mediated by epigenetic changes, which become more sensitive during this critical period of development under intense reorganization. Considering the nutritional transition and coexistence of the different forms of undernutrition in the low- and middle-income countries (LMIC); the global increase of NCDs, with a higher social and economic impact in those countries; the weak contribution of fixed genetic factors in the etiology of those diseases; and the inefficacy of current interventions, the implementation of DOHaD represents a potential strategy to benefit future generations. Considering that the dissemination of DOHaD have not followed its scientific progress, the goal of the present work was to develop an e-book targeting nutritionists and an article about the impacts of the COVID-19 pandemic in the perspective of DOHaD, intended to drive the science closer to those professionals and foster its implementation. It is a narrative review of the literature regarding scientific articles published in English and Portuguese on the data bases SciELO, PubMed and BVS, with no date limit. The work has highlighted that the challenge of the double burden of the diseases and the several forms of undernutrition in the LMIC, was aggravated by the pandemic, making intervention measures imperative due to its likely impact on the intergenerational cycle of NCD and the development of countries. By inching closer to nutritionists this science provides larger and more integrative education through technical training and interpersonal abilities that help activate biopsychosocial fragilities, and better intervention; providing short- and long-term results aiming to interrupt the NCD intergenerational cycle, as well as optimize the human capital, the work and income capacity of the future generation. It is concluded that the material developed is of great value, given that the dissemination of this knowledge should reach all nutritionists from all areas and be multiplied

A VIVÊNCIA DO PRECONCEITO APÓS A REVELAÇÃO DA SOROPOSITIVIDADE PARA O HIV / EXPERIENCE PREJUDICE AFTER THE DISCLOSURE OF SEROPOSITIVITY FOR HIV

Este estudo teve por objeto o processo de diagnóstico da soro positividade para o HIV e por objetivos: descrever processo de revelação do diagnóstico positivo para HIV e discutir a vivência do preconceito e suas consequências para vida cotidiana. Método: Entrevistas com 49 pessoas que vivem com HIV (PVHIV). Técnica de análise de conteúdo lexical, com auxílio do software Iramuteq 0.7 alpha 2. Resultados: As condições de vida de pessoas que vivem com HIV são permeadas pelo estigma, preconceito e discriminação. A revelação do diagnóstico para a sociedade não é uma tarefa fácil e nem sempre ocorre. Após impacto inicial do diagnóstico, a vida segue com mudanças cotidianas, os sentimentos de desespero e medo são aplacados com o tempo, entretanto o preconceito persiste. Conclusão: Os resultados mostram complexo cenário de se (con) viver com o vírus e /ou com a síndrome. A descoberta do diagnóstico, aceitação, decisão sobre revelação, reunir meios de enfrentamento do preconceito e prosseguir vivendo, exige que PVHIV tenham suporte e se reprogramem para enfrentar desafios diários.

This study had as its object the process of diagnosing serum positive for HIV and its objectives: to describe the process of disclosing the positive diagnosis for HIV and to discuss the experience of prejudice and its consequences for everyday life. Method: Interviews with 49 people living with HIV (PLHIV). Lexical content analysis technique, with the aid of the Iramuteq 0.7 alpha 2 software. Results: The living conditions of people living with HIV are permeated by stigma, prejudice and discrimination. Disclosing the diagnosis to society is not an easy task and does not always occur. After the initial impact of the diagnosis, life continues with daily changes, the feelings of despair and fear are appeased over time, however prejudice persists. Conclusion: The results show a complex scenario of (con) living with the virus and / or the syndrome. The discovery of diagnosis, acceptance, decision on disclosure, gathering means to face prejudice and continue living, requires that PLHIV have support and reprogram themselves to face daily challenges.

Caracterización de la población femenina con riesgo preconcepcional del municipio Arroyo Naranjo / Characterization of the Female Population with Preconception Risk of Arroyo Naranjo Municipality

Introducción: El riesgo reproductivo preconcepcional es la probabilidad que tiene una mujer no gestante de sufrir daño, ella o su producto, si se involucra en el proceso reproductivo. Objetivo: Caracterizar a la población femenina de 15 a 49 años de edad que presentan riesgo preconcepcional del municipio Arroyo Naranjo. Método: Se realizó un estudio descriptivo de corte transversal. El universo se constituyó de 603 mujeres en edad fértil pertenecientes al Consultorio No. 2 del Policlínico Párraga, municipio Arroyo Naranjo en el período 2015 -2016. La muestra fue de 160 mujeres que presentaban riesgo preconcepcional seleccionadas por la técnica de muestra no probabilística por criterio intencional (muestreo intencional). Se aplicó un cuestionario para recopilar los datos, con previo consentimiento informado, se revisaron las historias clínicas individuales, familiares y las tarjetas de riesgo preconcepcional. Se estudiaron las variables: edad, estado nutricional, hábitos tóxicos, uso de anticonceptivos, paridad, periodo intergénesico, las enfermedades crónicas asociadas.Los datos fueron procesados estadísticamente y, realizado el resumen, se expresaron en valores de frecuencia y porcentaje. Resultados: Los factores de riesgo preconcepcional que más influyeron fueron: la edad entre 15 y 19 años, el asma, la malnutrición por exceso, el periodo intergenésico mayor de 2 años, las multíparas y el hábito de fumar. El método anticonceptivo más utilizado fue el dispositivo intrauterino, Conclusiones: Se evidenció que con una adecuada dispensarización y seguimiento se puede garantizar que se arribe a la reproducción en condiciones óptimas(AU)

Introduction: Preconception reproductive risk is the probability that a non-pregnant woman has of suffering harm, on herself or her offspring, if she is involved in the reproductive process. Objective: To characterize the female population aged 15-49 years who present preconception risk. Method: A descriptive and cross-sectional study was carried out. The universe consisted of 603 women of childbearing age from the family medical office 2 of Párraga Polyclinic, Arroyo Naranjo Municipality (Havana, Cuba), in the period 2015-2016. The sample consisted of 160 women who presented preconception risk and selected using the nonprobabilistic sampling technique by intentional criteria (intentional sampling). A questionnaire was applied to collect data, with prior informed consent. Individual and family medical records and preconception risk cards were reviewed. The variables studied were age, nutritional status, toxic habits, use of contraceptives, parity, intergenic period, and associated chronic diseases. The data were statistically processed and, after the summary, they were expressed in frequency and percentage values. Results: The preconception risk factors that most influenced were age between 15 and 19 years, asthma, malnutrition in excess. The most used contraceptive method was the intrauterine device. Conclusions: It was evidenced that with adequate dispenzarization and follow-up, it can be guaranteed that reproduction be reached in optimal conditions(AU)

Caracterización del riesgo reproductivo preconcepcional en las mujeres en edad fértil / Characterization of the reproductive pre-conception risk in the women in fertile age

RESUMEN Fundamento: un adecuado control y manejo del riesgo preconcepcional permite determinar el estado de salud de cada mujer, lo que hace posible asumir un embarazo con mejores resultados para el binomio mediante el control de los factores de riesgo. Objetivo: caracterizar el comportamiento del riesgo reproductivo preconcepcional. Métodos: se realizó un estudio observacional, descriptivo y transversal en los consultorios del médico y la enfermera de la familia del Policlínico Pedro Borrás Astorga del municipio Pinar del Río, durante el año 2019. El universo fue de 4 772 mujeres en edad fértil. Se utilizó la estadística descriptiva y los resultados se reflejaron en tablas. Resultados: se identificaron 848 mujeres con riesgo reproductivo preconcepcional, un gran número de mujeres presentan enfermedades crónicas no transmisibles y algunas tienen más de una enfermedad. Predominó la malnutrición por defecto y por exceso, la hipertensión arterial y el asma bronquial y como antecedentes obstétricos, los abortos provocados, el período intergenésico corto y la hipertensión inducida por el embarazo, las anemias y los hijos pretérminos anteriores o bajo peso al nacer. Un alto porciento se encuentra controlado con algunas dificultades con las adolescentes. Conclusiones: el riesgo reproductivo preconcepcional es una problemática aún sin resolver ya que hubo un número de las mujeres que no estaban controladas. El seguimiento adecuado de las parejas con riesgo preconcepcional y su responsabilidad en la planificación de un embarazo contribuye al mejoramiento de la calidad de vida de madres e hijos.

ABSTRACT Background: an appropriate control and handling of the pre-conception risk allows determining the state of each woman's health, making possible to assume a pregnancy with better results for the binomial by means of the control of the risk factors. Objective: to characterize the behavior of the reproductive pre-conception risk. Methods: an observational, descriptive and traverse study was the carried out in the family doctor's and nurse offices of the Pedro Borrás Astorga Policlinic in Pinar del Río in 2019. The universe was constituted by 4772 women in fertile age. The descriptive statistic was used and the results were reflected in charts. Results: 848 women were identified with reproductive pre-conception risk, a great number of women present non-transmissible chronic illnesses and some have more than one illness. The malnutrition prevailed as much for defect as for excess, the arterial hypertension and the bronchial asthma and as obstetric antecedents, the induced miscarriages, the short birth intervals and the hypertension induced by the pregnancy, the anemia's and the previous preterm children and/or low-birth-weight babies. A high percent is controlled with some difficulties with the adolescents. Conclusions: the reproductive pre-conception risk is still a problem without solving since there was a number of the woman that they were not controlled. The appropriate control of the couples with pre-conception risk and its responsibility in the planning of a pregnancy contributes the improvement of the quality of mothers' and children's life.

Influencia del riesgo preconcepcional en la salud materna / Influence of preconceptional risk on maternal health

RESUMEN El riesgo preconcepcional está condicionado por una serie de factores, enfermedades o circunstancias únicas o asociadas que pueden repercutir desfavorablemente en el binomio madre / hijo durante la gestación, parto o puerperio. La prevención de la enfermedad y la muerte durante el proceso de reproducción, es uno de los pilares fundamentales para el desarrollo de la salud reproductiva. La morbilidad materna constituye uno de los aspectos más importantes para reflexionar. El objetivo de esta investigación es valorar la influencia del riesgo preconcepcional en la salud materna. Es indispensable, no solo en la atención de las gestantes, sino también para aquellas mujeres que desean ser madres en algún momento de su vida. Se ha adoptado un nuevo enfoque hacia el riesgo preconcepcional con acciones que contribuyan a mejorar la salud sexual y reproductiva en esta etapa en la vida de hombres y mujeres.

ABSTRACT Preconception risk is conditioned by a series of factors, diseases or unique or associated circumstances that can have an unfavorable impact on the mother - child binomial during pregnancy, delivery or puerperium. The prevention of disease and death during the reproductive process is one of the fundamental pillars for the development of reproductive health. Maternal morbidity is one of the most important aspects to reflect on. The objective of this research is to assess the influence of preconception risk on maternal health. It is essential, not only in the care of pregnant women, but also for those women who want to be mothers at some point in their life. A new approach has been adopted towards preconception risk with actions that contribute to improve sexual and reproductive health at this stage in the lives of men and women.

Preconception Care to Improve Pregnancy Outcomes: The Science

INTRODUCTION: In the last decades, improvements in the care of pregnancy and child development have been observed worldwide. However, pregnancy problems remain high in most countries. There was a concentration of care in the prenatal period as the primary approach for improving pregnancy results. Currently, attention to the care of pregnant women, women who have recently given birth, and newborns are focused on the care of preconception to improve the results of pregnancy and improve the outcomes of child growth and developmentOBJECTIVE: Describe the evidence for preconception care (PCC) and information to the health care provider, as well as describe instruments to present health care providers with PCC, its definition, its components, recommended interventions, and the scientific basis for recommendationsMETHODS: There was a search for published and unpublished literature related to scientific evidence for the effectiveness of PCC in improving pregnancy results. The search was carried out based on Pubmed and using data scraping techniques, in the material available on the internet and disseminated by international organizations, such as the World Health Organization and reports by government agenciesRESULTS: It is reported that the literature on the scientific basis for PCC is fragmented, and most publications discuss evidence of one or a few interventions, with the majority of reports considering PCC for specific populations, such as women with chronic health problems and couples with infertility. However, these publications do not offer a realistic view of the proposed PCC interventions, with the scientific evidence that supports them. The general aspects of the existing literature and the recommended preconceived care interventions are described, together with the quality of the scientific evidence and the strength of the recommendations behind each of these interventionsCONCLUSION: Many clinical interventions have been identified that could be offered to women before conception to help avoid adverse outcomes. Most of these interventions have scientific evidence to support their role in improving pregnancy outcomes. Therefore, it is recommended that clinical care providers incorporate evidence-based prejudice services in their daily care of women of reproductive age, in an effort to improve women's health before and during pregnancy, as well as improve pregnancy outcomes for women and their children

INTRODUÇÃO: As Nas últimas décadas, foram observadas melhorias no cuidado à gravidez e no desenvolvimento infantil em todo o mundo. No entanto, os problemas de gravidez continuam altos na maioria dos países. Houve uma concentração de cuidados no período pré-natal como a principal abordagem para melhorar os resultados da gravidez. Atualmente, a atenção aos cuidados de mulheres grávidas, mulheres que deram à luz recentemente e recém-nascidos está focada no cuidado de preconcepção para melhorar os resultados da gravidez e os resultados do crescimento e desenvolvimento infantilOBJETIVO: Descrever as evidências para os cuidado preconcepção (PCC) e informações para o profissional da saúde, bem como descrever instrumentos para apresentar aos profissionais de saúde o PCC, sua definição, seus componentes, intervenções recomendadas e a base científica para recomendaçõesMÉTODO: Houve uma pesquisa de literatura publicada relacionada a evidências científicas para a eficácia do PCC na melhoria dos resultados da gravidez. A pesquisa foi realizada com base no Pubmed e utilizando técnicas de raspagem de dados, no material disponível na internet e divulgado por organizações internacionais, como a Organização Mundial da Saúde e relatórios de órgãos governamentaisRESULTADOS: Relata-se que a literatura sobre a base científica do PCC é fragmentada e a maioria das publicações discute evidências de uma ou poucas intervenções, com a maioria dos relatórios considerando o PCC para populações específicas, como mulheres com problemas crônicos de saúde e casais com infertilidade. No entanto, essas publicações não oferecem uma visão realista das intervenções propostas do PCC, com as evidências científicas que as apoiam. Os aspectos gerais da literatura existente e as intervenções preconcebidas recomendadas são descritas, juntamente com a qualidade das evidências científicas e a força das recomendações por trás de cada uma dessas intervençõesCONCLUSÃO: Muitas intervenções clínicas foram identificadas que poderiam ser oferecidas às mulheres antes da concepção para ajudar a evitar resultados adversos. A maioria dessas intervenções possui evidências científicas para apoiar seu papel na melhoria dos resultados da gravidez. Portanto, recomenda-se que os prestadores de cuidados clínicos incorporem serviços de preconcepção baseados em evidências em seus cuidados diários a mulheres em idade reprodutiva, em um esforço para melhorar a saúde das mulheres antes e depois da gravidez. durante a gravidez, bem como melhorar os resultados da gravidez para mulheres e filhos

Preconception care: developing and implementing regional and national programs

INTRODUCTION: During the past few decades, health workers have come to agree that there is a very important place for preconception care (PCC) in improving maternal and infant pregnancy outcomes. The United States Centers for Disease Control and Prevention (CDC) and the World Health Organization issued recommendations encouraging countries to develop and implement preconception care programs. The reports include an in-depth discussion of the rationale and scientific evidence behind PCC as well as definitions, goals, components and recommended interventions to be included in PCC. These reports also offer very broad guidelines but do not offer details on how to develop and implement preconception care programsOBJECTIVE: The CDC and WHO reports identify the need for multi-sectoral engagement in developing and implementing preconception care programs and propose some activities and strategies to be considered in developing PCC programs. However, the recommendations fall short of specifying real steps that countries and regions should take in implementing PCC programs. In this publication we propose action steps for developing and implementing regional or national preconception care programsMETHODS: We reviewed the published and unpublished literature (using PubMed and the Internet) to identify reports that describe processes for developing and implementing PCC programs. We used information from the literature along with experiences we gained through our work and interaction with States and developing countries to prepare a detailed description of the steps involved in developing and implementing a PCC programRESULTS: We found very little in terms of "tools" for program managers and providers to use when developing and implementing PCC programs. We prepared a guide, including a summary of steps and a proposed timeline, for program directors to use for developing and implementing PCC programsCONCLUSION: Developing and implementing a sustainable PCC program should address issues related to educating the public, providers and policy makers about the benefits of PCC. It also includes establishing an infrastructure within the departments of health and ensuring resources to build, guide, monitor and evaluate the PCC program. Finally, implementation of a successful program depends heavily on the proper training of public health and clinical care providers in the delivery of the services included in the program

INTRODUÇÃO: Nas últimas décadas, os profissionais de saúde chegaram a um acordo sobre a importância dos cuidados preconcepção na melhoria dos resultados da gravidez materna e infantil. Os Centros dos Estados Unidos para Controle e Prevenção de Doenças (CDC) e a Organização Mundial da Saúde emitiram recomendações incentivando os países a desenvolver e implementar programas de assistência preconcepção. Os relatórios incluem uma discussão aprofundada da lógica e das evidências científicas por trás do PCC, bem como definições, objetivos, componentes e intervenções recomendadas a serem incluídas no PCC. Esses relatórios também oferecem diretrizes muito amplas, mas não oferecem detalhes sobre como desenvolver e implementar programas de assistência preconcepçãoOBJETIVO: Os relatórios do CDC e da OMS identificam a necessidade de envolvimento multissetorial no desenvolvimento e implementação de programas de assistência pré-conceitual e propõem algumas atividades e estratégias a serem consideradas no desenvolvimento de programas do PCC. No entanto, as recomendações não especificam as medidas reais que os países e regiões devem adotar na implementação de programas de assistência preconcepção. Neste artigo, propomos etapas de ação para o desenvolvimento e implementação de programas regionais ou nacionais de assistência pré-conceitualMÉTODO: Foi revisada a literatura publicada usando o PubMed para identificar relatórios que descrevem processos para o desenvolvimento e implementação de programas de assistência preconcepção. As informações da literatura foram utilizadas, juntamente com as experiências adquiridas por meio de nosso trabalho e interação com os Estados e os países em desenvolvimento, para preparar uma descrição detalhada das etapas envolvidas no desenvolvimento e na implementação de um programa de assistência preconcepçãoRESULTADOS: Pouco foi encontrado em termos de "ferramentas" para os gerentes e provedores de programas usarem ao desenvolver e implementar programas de assistência preconcepção. Este artigo foi preparado como um guia, incluindo um resumo das etapas e um cronograma proposto, para os diretores de programas usarem no desenvolvimento e na implementação de programas de assistência preconcepçãoCONCLUSÃO: O desenvolvimento e implementação de um programa sustentável do PCC deve abordar questões relacionadas à educação do público, fornecedores e formuladores de políticas sobre os benefícios do PCC. Também inclui o estabelecimento de uma infraestrutura nos departamentos de saúde e a garantia de recursos para construir, orientar, monitorar e avaliar o programa PCC. Finalmente, a implementação de um programa bem-sucedido depende muito do treinamento adequado dos prestadores de serviços de saúde pública e atendimento clínico na prestação dos serviços incluídos no programa

Preconception care to improve pregnancy outcomes: clinical practice guidelines

INTRODUCTION: There is scientific evidence that the health of women before pregnancy contributes to the maternal and infant outcomes of pregnancy. There is also scientific evidence that the health of women of reproductive age may be improved through the provision of Preconception Care (PCC). Preconception care includes interventions to assess, identify, address, and modify a woman's health conditions and risks to ensure that these health conditions and risks do not negatively affect the outcome of her pregnancy. Many of the medical conditions, environmental exposures, personal behaviors, and psychosocial risks associated with negative pregnancy outcomes have been identified and there are recommendations for including these conditions in PCC servicesOBJECTIVE: Our purpose is to present a tool for clinical care providers involved in delivering PCC services. We try to answer the following questions: what do providers actually do when a woman of reproductive age arrives at their offices? What questions to ask? What examinations to conduct? What laboratory tests to perform? And, what education and counselling to offer?METHODS: We reviewed published and un-published literature related to the scientific evidence for the effectiveness of PCC in improving pregnancy outcomes. We searched PubMed for published articles, and we searched the internet for unpublished reports prepared by international organizations such as the World Health Organization and reports from governmental agencies. We summarized the information and presented a comprehensive overview of actions that providers should take to address various risk behaviors, exposures and health conditionsRESULTS: Several scientists, countries, and international organizations have proposed answers to the above questions. However, there has been no consistency and there is not a single publication that includes a comprehensive compilation of the proposed actions. We summarized the recommended actions that clinical care providers should take in addressing various health conditions, risk behaviors, and exposuresCONCLUSION: It is recommended that all providers screen all women for their intentions to become pregnant and to provide them with appropriate services. Women should be referred to specialized care when risk behaviors and medical conditions that go beyond the skills and abilities of the primary care provider are identified

INTRODUÇÃO: Existem evidências científicas de que a saúde das mulheres antes da gravidez contribui para os resultados maternos e infantis da gravidez. Há também evidências científicas de que a saúde das mulheres em idade reprodutiva pode ser melhorada através da prestação de cuidados preconcepção. Os cuidados preconcepção incluem intervenções para avaliar, identificar, abordar e modificar as condições e riscos de saúde de uma mulher para garantir que essas condições e riscos não afetem negativamente o resultado de sua gravidez. Muitas condições médicas, exposições ambientais, comportamentos pessoais e riscos psicossociais associados a resultados negativos da gravidez foram identificados e existem recomendações para a inclusão dessas condições nos serviços de assistência preconcepçãoOBJETIVO: O objetivo deste estudo é servir como uma ferramenta para os prestadores de cuidados clínicos envolvidos na prestação de serviços de cuidados preconcepção. Tentamos responder às seguintes perguntas: o que os profissionais realmente fazem quando uma mulher em idade reprodutiva chega a seus escritórios? Que perguntas fazer? Quais exames realizar? Quais exames laboratoriais devem ser realizados? E que educação e aconselhamento oferecer?MÉTODO: Revisamos a literatura publicada e não publicada relacionada à evidência científica para a eficácia dos cuidados preconcepção na melhoria dos resultados da gravidez. Pesquisamos no PubMed por artigos publicados e pesquisamos na Internet relatórios não publicados preparados por organizações internacionais como a Organização Mundial da Saúde e relatórios de agências governamentais. Resumimos as informações e apresentamos uma visão abrangente das ações que os fornecedores devem adotar para abordar vários comportamentos de risco, exposições e condições de saúdeRESULTADOS: Vários cientistas, países e organizações internacionais propuseram respostas para as perguntas acima. No entanto, não houve consistência e não há uma única publicação que inclua uma compilação abrangente das ações propostas. Resumimos as ações recomendadas que os prestadores de cuidados clínicos devem adotar para lidar com várias condições de saúde, comportamentos de risco e exposiçõesCONCLUSÃO: Recomenda-se que todos os profissionais examinem todas as mulheres quanto à sua intenção de engravidar e forneçam-lhes os serviços adequados. As mulheres devem ser encaminhadas para atendimento especializado quando forem identificados comportamentos de risco e condições médicas que vão além das habilidades do prestador de cuidados primários

Comportamiento clínico epidemiológico de gestantes adolescentes con hipertensión arterial / Clinical epidemiological behavior of adolescent pregnant women with arterial hypertension

RESUMEN Fundamento: los trastornos hipertensivos son considerados como la principal causa de morbimortalidad materna y fetal a nivel mundial y en Ecuador. Objetivo: describir el comportamiento clínico epidemiológico de los trastornos hipertensivos de la gestación en adolescentes. Métodos: se realizó un estudio descriptivo que incluyó las 59 de gestantes adolescentes que presentaron preeclampsia o eclampsias atendidas en el contexto de la investigación durante el periodo comprendido entre mayo y diciembre de 2017. Se aplicó un cuestionario de investigación para obtener la información relacionada con las variables de investigación definidas. Resultados: promedio de edad de 16,32 años, predominio de gestantes con color de la piel no blanco y nulíparas. Elevado número de comorbilidades asociadas con predominio del sobrepeso e hipertensión arterial; predominio de pacientes que no habían recibido tratamiento preventivo con calcio y aspirina. La cefalea y el edema en miembros inferiores fueron las complicaciones maternas más frecuentes. El sufrimiento fetal, el crecimiento intrauterino retardado y la prematuridad fueron las complicaciones fetales con mayor frecuencia de presentación. Conclusiones: el patrón clínico y epidemiológico de las adolescentes con preeclampsia y eclampsia coincide con lo reportado en la literatura universal. Se evidencian falencias en el programa de control de riesgo preconcepcional y en la calidad del seguimiento de las gestantes que motiva un aumento de la incidencia de eclampsia y preeclampsia.

ABSTRACT Background: hypertensive disorders are considered as the main cause of maternal and fetal morbidity and mortality worldwide and in Ecuador. Objective: to describe the epidemiological clinical behavior of hypertensive disorders of pregnancy in adolescents. Methods: a descriptive study was carried out which included the 59 of pregnant teenagers who presented preeclampsia and/or eclampsia attended in the context of the research during the period from May to December 2017. A research questionnaire was applied to obtain information related to the variables of defined research. Results: average age of 16.32 years, predominance of pregnant women with non-white skin color and nulliparous. High number of comorbidities associated with a predominance of overweight and arterial hypertension; predominance of patients who had not received preventive treatment with calcium and aspirin. Headache and edema in the lower limbs were the most frequent maternal complications. Fetal distress, delayed intrauterine growth and prematurity were the fetal complications with the highest frequency of presentation. Conclusions: the clinical and epidemiological pattern of adolescents with preeclampsia and eclampsia coincides with that reported in the universal literature. Failures are evident in the preconception risk control program and in the quality of the follow-up of pregnant women that motivates an increase in the incidence of eclampsia and preeclampsia.

Advances in clinical management of pregnant women with preexisting diabetes / 中华围产医学杂志

Pregnant women with preexisting diabetes have increased adverse maternal and neonatal outcomes.Preconception planning is necessary for avoiding unintended pregnancies and mitigating risk of congenital defects.The recommended glycosylated hemoglobin goals are ＜6.5％ before conception and ＜6.0％ during pregnancy.Screening and management for diabetic complications are critical,strict blood pressure control goal need to be achieved,especially for those complicated by nephropathy.Continuous glucose monitoring during pregnancy might help improve blood glucose control for women with type 1 diabetes.Insulin is still the first-line therapy for pregnant women with preexisting diabetes.Optimization of glycemic control,appropriate medication regimens and close attention to comorbidities can help minimize the matemal and neonatal adverse outcomes and ensure the quality of clinical management for women with preexisting diabetes before,during,and after pregnancy.

Women's preconception health patterns in traditional Chinese medicine as a predictor of fertility outcomes / 中西医结合学报

OBJECTIVE@#To examine the association between traditional Chinese medicine (TCM), preconception health patterns and fertility outcomes.@*METHODS@#A community-based prospective cohort study was conducted in China. A total of 3012 newly married women who were willing to conceive within 2 years were enrolled in the study and took National Free Prepregnancy Checkups (NFPC). A reliably structured self-rating scale was used to measure the TCM preconception health patterns of the enrolled women. A 3-year follow-up was conducted to obtain the fertility outcomes, including pregnancy rate, time to pregnancy, spontaneous miscarriage and newborn status. Statistical analyses were conducted using Chi-square or Fisher's exact tests, logistic regression models, general linear models and the Cox proportional hazard model.@*RESULTS@#The fertility outcomes showed no statistic correlations to the terms of NFPC in this population. Approximately a half of the women (46.66%) had unhealthy patterns. Women with qi & blood-deficiency (odds ratio [OR] = 35.19, 95% confidence interval [CI] = 1.55-801.15) or qi-stagnation (OR = 4.55, 95% CI = 0.90-23.06) pattern took a longer time to get pregnant, and those with qi-stagnation (OR = 2.05, 95% CI = 1.1-3.82) or yang-deficiency (OR = 1.91, 95% CI = 1.12-3.25) pattern had a higher risk of spontaneous miscarriage.@*CONCLUSION@#Three unhealthy TCM patterns during the preconception period might be risk factors for low fecundity or poor pregnancy outcomes. The TCM preconception pattern identification may provide a convenient and effective way to screen for potential pregnancy risks beyond the NFPC. Further, appropriate interventions based on the TCM preconception health patterns are needed to improve quality in women's fecundability and birth outcomes.