Study of magnitude of grand multiparty and its perinatal outcome in a tertiary hospital of rural area in Maharashtra

Background: Grand multiparous pregnancies have been considered to be at higher risk of developing antenatal and perinatal complica?ons like pre-eclampsia, gesta?onal diabetes mellitus, anemia, antepartum hemorrhages, preterm labor, mal-presenta?on, mal-posi?on and feto-pelvic dispropor?on This study was done to know the magnitude of grand mul?para a?ending the ter?ary care center with possible complica?ons related to high parity. Objec?ves:To study the prevalence possible fetomaternal complica?ons associated with grand mul?para at rural setup. Methodology:Descrip?ve cross-sec?onal study conducted in medical college of rural area for 12 months. Grand mul?para with 5 or more deliveries before current pregnancy coming for antenatal checkup and delivery were enrolled. Antenatal history was recorded ?ll delivery and feto-maternal outcomes were noted. Results:Out of 1500 deliveries conducted during study period, 110 (7.5%) cases were grand mul?para. Majority of them (79.5%) were Muslim and 80% were anaemic. 60% delivered with FTND, and 25.4% had emergency LSCS with one intrauterine death and a single breach delivery. Predominantly preeclampsia (23.6%) and malpresenta?on (14.5%) were diagnosed as antepartum complica?ons. Almost one fi?h of them had postpartum hemorrhage which was controlled with no mortality. 13 (11.8%) grand mul?para women had s?ll birth or early neonatal death, though fetal distress was observed in 37 cases. Conclusion: Grand mul?party is s?ll a high-risk pregnancy associated with adverse maternal and fetal outcomes in our facility with mul?ple interrelated but mostly preventable causes.

Curetaje como tratamiento de apoyo en la reducción de la enfermedad hipertensiva inducida por el embarazo / Curettage as supportive therapy in reducing hypertensive disease induced by pregnancy

Introducción: el estado hipertensivo del embarazo es uno de los problemas obstétricos no resueltos más importante. El embarazo puede inducir elevación tensional y daño renal específico. Se han realizado algunos estudios que describen los cambios de la presión arterial durante todo el embarazo. En países donde el control prenatal no es adecuado, la preeclampsia provoca entre 40 y 80 por ciento de las muertes maternas. Se estima un total de 50 000 muertes por año. Objetivo: evaluar cómo se presenta la evolución de la presión arterial en el puerperio inmediato en pacientes con enfermedad hipertensiva inducida por el embarazo, sometidas a procedimiento de curetaje. Métodos: es un estudio comparativo con un grupo de intervención y un grupo control en el Hospital Universitario Dr. Joaquín del Valle Sánchez, Torreón. Coahuila, México. La intervención consistió en la realización del procedimiento de curetaje transcesárea en las pacientes con enfermedad hipertensiva inducida por el embarazo. Las mediciones principales fueron: el análisis de expediente clínico, perfil bioquímico completo, cifras tensionales. Resultado: la mayoría de las pacientes que acuden al Servicio de Ginecología y Obstetricia son adolescentes entre 14 y 20 años. Hubo una mejora significativa en la presión arterial sistólica a las 8 y 16 h, y una disminución a las 24 h de la presión sistólica y diastólica en pacientes sometidas al procedimiento de curetaje. Conclusiones: el uso del procedimiento de curetaje transcesárea en pacientes con enfermedad hipertensiva inducida por el embarazo disminuye considerablemente la presión arterial. Se sugiere el uso de este procedimiento en pacientes sometidas a cesárea en el Hospital Universitario Dr. Joaquín del Valle Sánchez y otros centros de salud(AU)

Introduction: Hypertensive pregnancy status is one of the obstetrical most important unsolved problems. Pregnancy can induce specific tensional elevation and kidney damage. There have been some studies describing changes in blood pressure throughout pregnancy. In countries where prenatal care is not adequate, preeclampsia causes 40 and 80 percent of maternal deaths. 50 000 deaths per year are estimated. Objective: Evaluate how the evolution of blood pressure in the immediate postpartum period in patients undergoing curettage procedure is presented due to pregnancy-induced hypertensive disease. Methods: A comparative study with an intervention group and a control group was conductedat Dr. Sanchez Joaquin Valley University Hospital, in Torreon, Coahuila, Mexico. The intervention consisted of carrying out the process of trans-cesarean curettage in patients with pregnancy-induced hypertensive disease. The main readings were the analysis of medical records, complete biochemical profile, and pressure figures. Result: Most patients who come to the service of Gynecology and Obstetrics are teenagers 14-20 years. There was significant improvement in systolic blood pressure at 8 and 16 h, and decreased to 24 in systolic and diastolic blood pressure in patients undergoing the procedure of curettage. Conclusions: The use of curettage procedure after cesarean section in patients with hypertensive disease induced by pregnancy significantly lowers blood pressure. The use of this procedure is suggested in patients undergoing cesarean section at suggested Dr. Joaquín del Valle Sánchez University Hospital and other health centers(AU)

Respiratory insufficiency in a patient with preeclamsia and hypothyroidism developed after general anesthesia for emergency cesarean section: A case report / 대한마취과학회지

Anesthesia and surgery in a patients with undiagnosed or untreated hypothyroidism can carries the risk of potential complications such as prolonged unconsciousness, respiratory insufficiency, hypotension, hyponatremia, congestive heart failure, and even coma. A 33-year-old gravida was admitted at 36 weeks gestation with hypertension, proteinuria, generalized edema, and intrauterine fetal growth retardation. She had thyroidectomy for thyroid mass six years ago. Because of doubt of uterine abruption, emergency cesarean section was performed without result of thyroid function test. Preeclamsia and mild hypothyroidism show similar symptoms and it can make difficult to diagnose hypothyroidism. We experienced delayed recovery and respiratory insufficiency in a patient with preeclamsia and undetected hypothyroidism during emergence from general anesthesia. She was fully recovered after ventilatory care in intensive care unit.

A Clinical Experience in 16 Pregnancies with Hemolysis, Elevated Liver Enzymes, and Low Platelets (HELLP Syndrome) / 대한산부인과학회잡지

OBJECTIVE: Our purpose was to describe the clinical progress and the maternal and fetal outcome in 16 pregnancies complicated by the HELLP(hemolysis, elevated liver enzymes, low platelet). Material: We reviewed the maternal and neonatal charts from 16 consecutive pregnancies complicated by the HELLP syndrome among 302 pregnancies complicated by preeclamsia and eclamsia managed at our hospital during the period of 4 years from June 1994 through June 1998. The HELLP syndrome was defined by previously published laboratory criteria. We assessed the time of onset, presenting symptom, laboratory finding, mode of delivery, fetal and maternal complication in each case. We also reviewed the clinical finding in detail in the case resulted in maternal death. RESULTS: In regards to the time of onset, 15 cases (93.7%) occurred at antepartum period and only 1 case (6.2%) occurred at postpartum period. Among the 15 cases occurred at antepartum period, 13 cases (81.25%) developed at 27 to 36 weeks gestation and 2 cases (12.5%) developed at near term. In regards to the presenting symptom, twelve patients (75%) complained of right upper quardrant or epigastric pain. Of 16 patients, 12 patients (75%) experienced headache and 10 patients (62.5%) complained of nausea, or vomiting and 5 patients (31.2%) had visual disturbance. The laboratory finding of all 16 cases were as follow; the mean level of platelet: 68700/mm3 (range: 48000 to 91700), the mean level of serum asparate aminotransferase: 335 IU/L (range: 62 to 135), the mean level of lactic dehydrogenase: 910 IU/L (range: 558 to 5794), and the mean level of total bilirubin: 2.6 mg/dl (range: 0.7 to 10.4). To review the mode of delivery, cesarean sections were done on 10 patients (62.5%) including 7(43.7%) emergency and 3(18.7%) elective operations. However, 6 patients (37.5%) delivered vaginally. Maternal complications were as follow; abruptio placenta in 1 case (6.2%), DIC in 2 cases (12.5%), pulmonary edema in 3 cases (18.7%), pleural effusion in 4 cases (25%), renal failure in 4 cases (25%), and 1 case of death. Fetal and neonatal outcome was assessed; 9 cases of intrauterine growth retardation (56.2%), meconium stained in 3 cases (18.7%), 2 stillbirth (12.5%), and 2 neonatal death (12.5%). CONCLUSION: HELLP syndrome is associated with serious maternal and fetal morbidity and mortality.

Bronchospasm After Intravenous Esomolol Injection with Rapid Sequence Induction for Preeclamptic Patient: Case report / 대한마취과학회지

Esmolol is rapid ultrashort-acting, cardioselective beta1-adrenergic blocker and that is used for attenuation of acute hypertension associated with rapid sequence induction of general anesthesia. A 35-year-old severe preeclamptic patient was scheduled for elective cesarean section. After preoxygenation, anesthesia induced with using penthotal sodium 250 mg, esmolol 25 mg, and succinylcholine 62.5 mg for endotrachial intubation. We detected to increase airway resistance during manual ventilation. Breathing sound was auscultated wheezing and ronchi. And then cyanosis was developed and oxygen saturation was decreased to below 75%. After 20 min, patient's color was returned to pink and patient's self-respiratory function was good. Bronchospasm occured because that beta-adrencergic blockade with esmolol, by leaving the parasympathetic and alpha-adrencrgic influence relatively unopposed. We report bronchospasm after esmolol 25 mg was injeected for attenuation of acute hypertensive response for cesarean section of preeclamptic patient with rapid sequence induction of general anesthesia.

Bronchospasm After Intravenous Esomolol Injection with Rapid Sequence Induction for Preeclamptic Patient: Case report / 대한마취과학회지

Esmolol is rapid ultrashort-acting, cardioselective beta1-adrenergic blocker and that is used for attenuation of acute hypertension associated with rapid sequence induction of general anesthesia. A 35-year-old severe preeclamptic patient was scheduled for elective cesarean section. After preoxygenation, anesthesia induced with using penthotal sodium 250 mg, esmolol 25 mg, and succinylcholine 62.5 mg for endotrachial intubation. We detected to increase airway resistance during manual ventilation. Breathing sound was auscultated wheezing and ronchi. And then cyanosis was developed and oxygen saturation was decreased to below 75%. After 20 min, patient's color was returned to pink and patient's self-respiratory function was good. Bronchospasm occured because that beta-adrencergic blockade with esmolol, by leaving the parasympathetic and alpha-adrencrgic influence relatively unopposed. We report bronchospasm after esmolol 25 mg was injeected for attenuation of acute hypertensive response for cesarean section of preeclamptic patient with rapid sequence induction of general anesthesia.