ABSTRACT
Objective To evaluate the clinical management and outcome in pregnancy complicated with preterm premature rupture of membranes (PPROM). Methods The clinical data of 98 patients with PPROM were retrospectively analyzed. 20 patients with PPROM at 28 ～ 33 +6 weeks were selected as the early group, while 78 patients with PPROM at 34 ～ 36 +6 weeks as the late group. Results The puerperal infection, postpartum hemorrhage and delivery methods had no statistical differences between early group and late group (all P＞0. 05). The neonatal Apgar Score in early group was less than that in late group ( all P ＜ 0. 05). The incidences of neonatal respiratory distress syndrome,infection and death in early group were higher than that in late group. There were significant differences between two groups (all P ＜ 0.05). Conclusion Pregnancy between 28 and 34 weeks gestation with PPROM should be managed expectantly to protect fetus to 34 weeks and over. Pregnancy should be terminated appropriately by use of suitable delivery method. The above methods could effectively decrease occurrence incidences of complications and mortality.