ABSTRACT
OBJECTIVES: This study aimed to investigate the prospective associations of premenstrual dysphoric disorder (PMDD) with quality of life, socio-occupational function and disability. METHODS: 170 nurses were recruited from two general hospitals. Interviews were made at baseline and at four follow-up points (two mid follicular phases and two late luteal phases of the two consecutive menstrual cycles). The baseline evaluation consisted of sociodemographic characteristics and menstrual history. PMDD was diagnosed by DSM-IV criteria after observation of the two menstrual cycles. The follow-up evaluations were consisted of the World Health Organization Quality of Life-Brief form, the Social and Occupational Functioning Assessment Scale, and the World Health Organization Disability Assessment Scale-II. RESULTS: PMDD was detected 15 (8.8%) of 170 participants. The PMDD group showed significantly worse quality of life and socio-occupational functioning than the none-PMDD group particularly at the late luteal phases. No significant differences were found in sociodemographic characteristics and menstrual history between those with and without PMDD. CONCLUSION: PMDD was prospectively associated with worse quality of life and socio-occupational functioning in this study group.
Subject(s)
Female , Diagnostic and Statistical Manual of Mental Disorders , Follow-Up Studies , Hospitals, General , Menstrual Cycle , Prospective Studies , Quality of Life , World Health OrganizationABSTRACT
Many reproductive women, at least 20-50%, suffered from premenstrual syndrome and 2-8% of them have premenstrual dysphoric disorder(PMDD). Prospective daily records during 2 menstrual cycles are required to differentiate PMDD from other various similar conditions such as concurrent psychiatric or medical diseases or their premenstrual magnification and also to determine the efficacy of treatment. The etiology of PMDD is largely unknown. Recently as several randomized placebo-controlled trial in women with PMDD have reported the efficacy of serotonin reuptake inhibitors(SSRIs), SSRIs have been preferred to other treatment regimens though response rates to SSRIs were variable with high placebo response rate and though their long-term and preventive effect were not yet determined.
Subject(s)
Female , Humans , Menstrual Cycle , Premenstrual Syndrome , Prospective Studies , SerotoninABSTRACT
0.05).Conclusions: (1) The more severe of learning stress, the higher level of PMDD. (2) There was no difference in anxiety and depression between the students who suffered from PMDD and the who didn't. (3) The students who suffered from PMDD had more psychosomatic symptoms.