ABSTRACT
El nacimiento prematuro favorece la aparición de alteraciones visuales donde los defectos refractivos altos prevalecen, pues se afecta el proceso de emetropización. La revisión tuvo como objetivo describir la miopía del prematuro como resultado de una alteración en el desarrollo del segmento anterior. La hipermetropía se observa de mayor cuantía en estos pacientes, así como el astigmatismo significativo. Entre los factores de mayor peso se encuentran, además de la prematuridad, el bajo peso al nacer, la presencia de retinopatía del prematuro y su tratamiento con láser. Las evaluaciones oftalmológicas sistemáticas permiten detectar y corregir a tiempo estas alteraciones y favorecen una función visual óptima con menor riesgo de ambliopía. Los artículos que se consultaron son fundamentalmente de los últimos cinco años, en idiomas español e inglés, disponibles en textos completos y resúmenes en algunas bases de datos como PubMed, Ebsco, Google Académico y Scielo(AU)
Preterm birth may affect the emmetropization process, leading to the appearance of visual alterations characterized by a high prevalence of refractive defects. A case is described of myopia of prematurity resulting from an alteration in the development of the anterior segment. Hyperopia and astigmatism are significantly frequent in these patients. Other causative factors besides prematurity are low birth weight, the presence of retinopathy of prematurity and its treatment with laser therapy. Systematic ophthalmologic evaluation allows early detection and correction of these alterations, leading to optimal visual function and a lower risk for amblyopia. The articles consulted are mainly from the last five years, written in Spanish or English, and available as full texts and abstracts in databases like PubMed, EBSCO, Google Scholar and SciELO(AU)
Subject(s)
Humans , Infant, Newborn , Astigmatism , Retinopathy of Prematurity/etiology , Amblyopia , Myopia , Databases, Bibliographic , Premature BirthABSTRACT
OBJECTIVE:To investigate the effects and safety of erythropoietin on nerve function and brainstem auditory evoked potential in the preterm children with brain damage. METHODS:46 preterm children with brain damage were randomly di-vided into treatment group and control group,with 23 cases in each group. Control group received conventional symptomatic treat-ment as respiratory support,nutritional support,vitamin K supplement and ganglioside. Treatment group was additionally given rhE-PO for injection (CHO cell) 500 IU/kg hypodermically,3 times a week,on the basis of control group. Both group received 3-4 weeks of treatment continuously. MDI,PDI,the content of serum nerve injury factor(NSE,S-100β),latent period and peak inter-val of brainstem auditory evoked potential were compared between 2 groups before and after treatment,and the occurrence of ADR was observed in 2 groups. RESULTS:There was no statistical significance in MDI,PDI,the content of serum nerve injury mole-cule,latent period and peak interval of brainstem auditory evoked potential between 2 groups before treatment (P>0.05). After treatment,MDI and PDI of 2 groups increased significantly,while the content of serum nerve injury factor,latent period and peak interval of brainstem auditory evoked potential decreased significantly;the treatment group was better than the control group,with statistical significance (P<0.05). No obvious ADR was found in 2 groups. CONCLUSIONS:Erythropoietin can significantly im-prove intelligence development,protect the damaged nerve cells and auditory nerve pathways with good safety.
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AIM:To investigate the clinical value of wide angle digital imaging system ( RetCam Ⅱ) for the screening of retinopathy of premature infants ( ROP) . ●METHODS: A total of 200 cases ( 400 eyes ) in preterm children were selected Jan. 2012 to Dec. 2015 in line with obstetric screening criteria using RetCamⅡROP screening children for binocular indirect ophthalmoscopy results as the gold standard, RetCamⅡ for screening value of ROP in premature children. ●RESULTS:The screening of 200 cases ( 400 eyes ) in premature infants, binocular indirect ophthalmoscopy were detected 63 eyes with ROP (15. 8%), 337 normal eyes, 42 eyes with ROP phase l, 14 eyes with phase ll, 7 eyes with phase lll, no one with ROP phase lV and ROP phaseⅤ. A total of a 64 eyes with ROP were screened by RetCam ll, which the misdiagnosis in 5 eyes, diagnostic level decreased in 6 eyes. The consistency of RetCam ll detection results with binocular indirect ocular fundus examination results was 0. 814, P ● CONCLUSION: RetCam Ⅱ in preterm children ROP screening has high clinical value.
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ObjectiveTo investigate the early screening; treatment and care methods of the retinopathy (ROP) of preterm children. Methods210 premature children born in our hospital were selected to conduct eye screening,treatment and care from January to December 2009.The nursing key points were summarized. ResultsAmong 210 preterm children,15 cases occurred ROP,the rate was 7.1％.Lesions appeared to be the threshold for laser treatment in 8 patients(16 eyes),accounting for 3.8％.The ROP morbidity rate was higher in birth weight ≤ 1000 g group than that in birth weight ＞ 1000 g group,higher in gestational age ≤32-week group than that in gestational age＞ 32 weeks,higher in the inhalation oxygen concentration ≤ 96％ group than in inhalation oxygen concentration ＞ 96％ group.Significant difference existed in ROP and non-ROP preterm children. ConclusionsThe incidence of retinopathy of premature children was closely related with low gestational age,low birth weight and prolonged and high-concentration oxygen inhalation,timely screening and early intervention care should be given to them.
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O objetivo deste estudo foi analisar o valor preditivo da Avaliação Neurológica Amiel-Tison no desenvolvimento cognitivo de crianças nascidas pré-termo. Foi estudada uma amostra de 23 crianças pré-termo, com idade cronológica entre 10 e 36 meses, que haviam sido submetidas à avaliação neurológica durante internação na UTINeo. A avaliação cognitiva foi realizada através do Screening Test das Escalas Bayley-III. Pouco mais de 78 por cento das crianças obtiveram resultados normais no exame neurológico e na avaliação cognitiva. Mas houve dois casos de falsos positivos e dois de falsos negativos. Segundo a análise estatística realizada através do teste Qui-quadrado (p=0,05), o instrumento Amiel-Tison não teve valor preditivo significativo para o desenvolvimento cognitivo (p=0,083). Apesar das limitações, este estudo vem no sentido de ressaltar a importância de pesquisas que indiquem um método sistemático de avaliação neurológica e neuropsicológica para esta população de risco, para que ocorram investimentos em ações preventivas e interventivas adequadas.
The purpose of this study was to analyze the predictive value of Amiel-Tison Neurological Assessment in the cognitive development of preterm children. The sample consisted of 23 children born preterm, between 10 and 36 months of chronological age, who had undergone neurological assessment during hospitalization in the NICU. The cognitive assessment was performed by the Screening Test of Bayley-III. Approximately 78 percent of children had normal results on neurological examination and cognitive assessment. But there were two cases of false positives and two cases of false negatives. According to statistical analysis using Chi-square (p=0.05), the instrument Amiel-Tison had no significant predictive value for cognitive development (p=0.083). Despite the limitations, this study contributed to emphasize the relevance of more research that indicate a systematic method of neurological and neuropsychological assessment of this population, that can be invested in preventive and interventional measures.
Subject(s)
Child Development , Infant, Premature , Diagnostic Techniques, NeurologicalABSTRACT
ObjectiveTo investigate the delayed umbilical cord clamping in preterm children of anemia in premature children.Methods60 preterm children were randomly divided into study group and control group 30 patients in each group.The control group was taken regular off umbilical,the observation group delay 90s(after birth at least 2min) off umbilical.ResultsThe Hb, HCT, and SI in the postnatal 1,2,4,8 weeks were significantly lower than the observation group, the difference was statistically significant (all P ＜ 0.05), and the control group after birth in preterm children Ret in the first week was significantly higher than 2,4 in the observation group, the difference was statistically significant(all P ＜ 0.05) ; The observation group at 6 months the incidence of anemia(13.3％) and transfusion rate(6.7％) were significantly lower than the control group(43.3％ ,33.3％) ,the difference was statistically significant(all P ＜0.01).ConclusionDelyed umbilical cord clamping in preterm children could increase the redblood cells and iron reserves in preterm children, reduce the incidence of anemia caused by blood transfusion, was worthy of clinical application.
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This study was performed to evaluate the utilization and outcomes of palivizumab in high risk children born prematurely with chronic lung disease (CLD). A retrospective review of 128 patients was conducted from September 2004 to March 2009 at the Ajou University Hospital. All patients were diagnosed with CLD, were born at < or =35 weeks of gestation, were <2 yr old at the onset of respiratory syncytial virus (RSV) season, and had received medical therapy within six months prior to the RSV season. Fifty-three patients did not receive palivizumab prophylaxis and 75 patients received at least one dose of palivizumab. There were no statistically significant differences between the patients with and without palivizumab prophylaxis with regard to demographic characteristics and risk factors for RSV infection. There were no systemic adverse responses. Compliance with the course of prophylaxis was 92.2%. Hospitalization associated with RSV occurred in 12 cases (22.6%) in the group without prophylaxis and in three cases (4.0%) with prophylaxis. Palivizumab prophylaxis significantly reduced the frequency of RSV-related hospitalization in preterm children with CLD. This is the first retrospective review of palivizumab prophylaxis in Korea. Palivizumab is effective and well tolerated in high risk prematurely born children.