ABSTRACT
With reference to Xin Diao Sun Zhen Ren Qian Jin Fang,the Xindiao's edition of Bei Ji Qian Jin Yao Fang(Invaluable Prescriptions for Emergencies)which was the popular edition before official block printing of the Northern Song Dynasty),we analyzed the collation for proof-reading method in Song's edition of Bei Ji Qian Jin Yao Fang(Invaluable Prescriptions for Emergencies)printed by Bureau of Correcting Medical Books in Northern Song Dynasty.The results showed that there are many omissions and erroneous annotations in the collation records of the Song's edition,indicating that the judgment of the scholarly value of textual difference and the criteria of selecting and omitting the annotations of textual difference in the Song's edition require further studies.Some of the collation records in the Song's edition were consistent with those of the Xindiao's edition,suggesting that the Xindiao's edition was referenced during the collation by the officials of the Song Dynasty.In compiling Bei Ji Qian Jin Yao Fang,the original edition and the collated edition were not defined by the officials of the Song Dynasty,multiple hand copies in Tang Dynasty were collected for reference,and multiple medical records in Tang Dynasty and before Tang Dynasty were referenced.For the proofreading work of the Bureau for Revising Medical Books was in charge by scholars and Confucian ministers,we proposed that the complexity during compiling the book and the uncertainty of the text should be paid more attention.It is necessary to further clarify the basic issues such as the origin,basic structure,references and citation methods of the Song's edition,so as to provide reference for understanding the characteristics of the edition correctly and making effective use of the literature.
ABSTRACT
In reference to the photocopy and
Subject(s)
Acupuncture , Acupuncture Therapy , China , MoxibustionABSTRACT
Tributo in memoriam a Don Oscar Pino Galarza (1926-2014), secretario y asistente administrativo de la Revista de Neuro-Psiquiatría por espacio de más de sesenta años, colaborador cercano de los Profesores Honorio Delgado, primero, y Javier Mariátegui, después. Luego de breves anotaciones biográficas, obtenidas mediante una entrevista con la esposa e hijos de Don Oscar, se describen rasgos fundamentales de su personalidad y su trabajo. En la Revista, su labor fue multidimensional al haber estado envuelto en tareas secretariales, administrativas, logísticas y editoriales que desempeñó con singular eficiencia, devoción, lealtad y modestia. Estas cualidades y su nobleza espiritual fueron evidentes en momentos decisivos de la trayectoria académica y editorial de los dos primeros Directores de nuestra publicación. Se reconocen así la vida y la obra de un auténtico orfebre, de alguien que reflejó lo mejor y más alto de una genuina calidad humana, más allá de orígenes sociales, documentos burocráticos o formalidades institucionales.
A tribute to Don Oscar Pino Galarza (1926-2014), secretary and administrative assistant of the Revista de Neuro-Psiquiatría for over 60 years, closely working with Professors Honorio Delgado, first, and Javier Mariátegui, later. After brief biographic notes obtained from an interview with Don Oscars wife and children, fundamental features of his personality and his work are described. At the Revista, his activity was multidimensional as he was involved in secretarial, administrative, logistic and editorial tasks which he conducted with unique efficiency, devotion, loyalty and modesty. These qualities and his spiritual nobility were evident during decisive moments in the academic and editorial careers of the first two Directors of our journal. Thus, due recognition is given to life and the work of a genuine goldsmith, one who reflected the best and the highest of a true human quality, beyond social origins, bureaucratic documents or institutional formalities.
Subject(s)
Humans , Male , Biographies as Topic , Periodicals as TopicABSTRACT
To analyze the active sites of various prokaryotic and eukaryotic DNA polymerases and propose a plausible mechanism of action for the polymerases with the Escherichia coli DNA polymerase I as a model system. Study Design: Bioinformatics, Biochemical and X-ray crystallographic data were analyzed. Place and Duration of Study: Department of Molecular Microbiology, School of Biotechnology, Madurai Kamaraj University, Madurai – 625 021, India. From 2007 to 2012. Methodology: The advanced version of T-COFFEE was used to analyze both prokaryotic and eukaryotic DNA polymerase sequences. Along with this bioinformatics data, X-ray crystallographic and biochemical data were used to confirm the possible amino acids in the active sites of different types of polymerases from various sources. Results: Multiple sequence analyses of various polymerases from different sources show only a few highly conserved motifs among these enzymes except eukaryotic epsilon polymerases where a large number of highly conserved sequences are found. Possible catalytic/active site regions in all these polymerases show a highly conserved catalytic amino acid K/R and the YG/A pair. A distance conservation is also observed between the active sites. Furthermore, two highly conserved Ds and DXD motifs are also observed. Conclusion: The highly conserved amino acid K/R acts as the proton abstractor in catalysis and the YG/A pair acts as a “steric gate” in selection of only dNTPS for polymerization reactions. The two highly conserved Ds act as the “charge shielder” of dNTPs and orient the alpha phosphate of incoming dNTPs to the 3’-OH end of the growing primer.