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1.
Journal of the Korean Ophthalmological Society ; : 277-284, 1998.
Article in Korean | WPRIM | ID: wpr-149054

ABSTRACT

Viscoelastic substance which is one of the most important thing in anterior segment surgery sells many kinds as to its unique properties. The complications during its use are acute postoperative intraocular pressure elevation, corneal edema, severe ocular pain, blurred vision. The extent of elevation, peak time and normalized time of intraocular pressure can be varied by operative technique, amount of residual viscoelastics in anterior chamber, kinds of viscoelastics. To compare the safety of Healon GV and Provisc with Healon, we injected the same amount of those three viscoelastics into anterior chamber of 27 rabbits divided by three groups and examined the degree and change of intraocular pressure elevation, corneal edema, intraocular inflammation, maintenance of anterior chamber. Healon GV showed the persistent intraocular pressure elevation immediately after injection and normalized at 24 hours. Healon and Provisc showed elevated pressure at 7 and 5 hour but normalized within 12 hour. Corneal thickness increased significantly at 1 to 7 hour in Healon and Healon GV group and continued to 24 hour in Healon GV group and there was no significant pressure change in Provisc group compared with preinjection status. There were no significant differences in intraocular inflammation, amintenance of anterior chamber between three viscoelastics. Healon GV shoed more frequent, higher intraocular pressure elevation as compared to the other two viscoelastics, but pressure was normalized within 24 hour. From the above results, it is concluded that Healon GV can be used well with caution and Provisc can be used widespreadly due to its minor complication, too.


Subject(s)
Rabbits , Anterior Chamber , Corneal Edema , Hyaluronic Acid , Inflammation , Intraocular Pressure
2.
Journal of the Korean Ophthalmological Society ; : 2952-2958, 1998.
Article in Korean | WPRIM | ID: wpr-213328

ABSTRACT

Viscoelastics which are used in intraocular surgery sell many kinds as to its unique properties. We intended to valuate the clinical usefulness of three viscoelastics, Healon, Healon GV and Provisc. We performed phacoemulsificatioin and posterior chamber intraocular lens implantation in 26, 28, 29 eyes with each viscoelastics and measured the corneal thickness at preoperatively, postoperative 1 day, 1 week, 1 month, 2 months, 5 months and endothelial cell count at preoperatively, postoperative 2 months. We also analysed the anterior chamber maintenance and easiness of injection and removal during operation, In Healon used group, Preoperative corneal thickness was 549.7+/-24.3micrometer, in Healon GV group, 550.1+/-28.7micrometer, in Provisc group, 543.1+/-39.0micrometer and which were changed into 552.1+/-39.0micrometer, 533.1+/-21.1micrometer, 522.2+/-32.0micrometer at postoperative 5 months respectively, but there was no statistically significant difference between preoperative and postoperative status in all three groups. There was a tendency of slight reduction of endothelial cell count at postoperative 2 month in three groups, but it wasn`t statistically significant, too. Healon GV and Provisc were better in anterior chamber maintenance but injection into anterior chamber and removal by irrigation and aspiration were more easy in Healon used group. So, we suggest all three viscoelastics has hood endothelial protective effect and can be used freely as to their unique properties and the operative situation.


Subject(s)
Anterior Chamber , Endothelial Cells , Hyaluronic Acid , Lens Implantation, Intraocular
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