Two Cases of Pruritic Urticarial Papules and Plaques of Pregnancy in the Postpartum / 대한피부과학회지

Pruritic urticarial papules and plaques of pregnancy (PUPPP), also known as a polymorphic eruption of pregnancy, is the most common dermatosis of pregnancy. Typically, PUPPP starts with erythema and urticarial papular eruption in the abdominal striae and may extend to the buttocks and thighs. It usually evolves in the third trimester and resolves rapidly in the postpartum. It is not usually recurrent in subsequent pregnancies. We report herein two patients with postpartum PUPPP.

Pruritic Urticarial Papules and Plaques of Pregnancy: Clinical Experience with 22 Patients / 대한피부과학회지

BACKGROUND: Pruritic urticarial papules and plaques of pregnancy is a common benign dermatosis of pregnancy. It occurs mainly in primigravidas in the third trimester, it resolves spontaneously or with delivery, and it is usually responsive to topical treatment. The morphological spectrum of pruritic urticarial papules and plaques of pregnancy includes (1) urticarial papules and plaque (type I), (2) non-urticarial erythematous patches that are discrete or confluent and they are surrounded by tiny papules or vesicles, or clusters or sheets of 1-mm to 2-mm erythematous papules (type II) and (3) a combination of these features (type III). OBJECTIVE: This study evaluated our clinical experience with 22 Korean patients with pruritic urticarial papules and plaques of pregnancy. METHODS: From June 1997 to August 2008, 22 patients with pruritic urticarial papules and plaques of pregnancy were evaluated. The clinical manifestations, the lesion distribution and the obstetric and pediatric findings were retrospectively investigated with using the patients' medical records and clinical photographs. RESULTS: There were 9, 11 and 2 patients with types I to III, respectively. Many patients (n=14) were primigravida and the mean time of onset was a gestational age of 29.8 weeks. There were no pediatric problems such as intra-uterine growth retardation, or a small or large size for the gestational age.Most of the patients (n=20) were treated with topical corticosteroid or antihistamine; there was one case of recurrent pruritic urticarial papules and plaques of pregnancy. CONCLUSION: Pruritic urticarial papules and plaques of pregnancy usually occur in primigravidas, but this can also occur in multigravida patients. The number of patients with pruritic urticarial papules and plaques of pregnancy and who had obstetric obesity, a multiple pregnancy or pregnancy-induced hypertension was fewer than we expected. Pruritic urticarial papules and plaques of pregnancy can be divided into three categories, although this is rather redundant because the disease prognosis and treatments are not different according to the type.

A Case of Pruritic Urticarial Papules and Plaques of Pregnancy (PUPPP) Syndrome Supposedly Caused by the Paternity in Late Pregnancy / 대한주산의학회잡지

Pruritic Urticarial Papules and Plaques of Pregnancy (PUPPP) is a common dermatosis of pregnancy which usually occurs in the third trimester and generally in that of primigravida. Clinical feature is characterized by tiny erythematous papules which soon coalesce to form large, erythematous plaques. It generally occurs in abdomen, buttocks, thighs and upper inner arms. Since 1979 when Lawley et al. first described and reported PUPPP, there has been a lot of reports on PUPPP but the etiology is still not known. Many etiologic factors were reported but paternity as an etiologic factor was rarely reported. We had a very rare case which showed paternity could be one of the possible etiologic factors and we would like to share our case though this report.

Three cases of pruritic urticarial papules and plaques of pregnancy / 대한피부과학회지

We roport herein three cases of pruritic urticarial papules and plaques of pregnancy in two primigravidas and one multigravida in erythematous papules and urticarial plaques on both thighs, buttock and upper extremites. In the second case, lesions initially developed on both thighs and then preaded on abdomen, back and exter ities. Abdomen, thighs and extremites were involved in the third case. Histopathologic findings revealed acanthosis orfocal spongiosis in epidermis and lymphocytic perivascular infiltration with or without eosinophilsn dermis. They were treated with systemiror topical steroids and, mtihistamines. Itching was relieved within a few days after therapy and skin lesions resolved spontaneously after delivery.

A Case of Pruritic Urticarial Papules and Plaquesof Pregnancy / 대한피부과학회지

We report herein a case of PUPPP in a 26-year-old-primigravida with urticarial papules and plaques on the abdomen and thigh which developed at 39th week of the pregnancy. Histopathologic findings revealed focal spongiosis in the epidermis and lymphocytic perivascular infiltration in the dermis. The skin lesion resolved spontaneously after delivery and the new-born had no specific abnormalities.