ABSTRACT
La calcifilaxis se caracteriza por una intensa deposición de calcio en pequeños vasos sanguíneos, piel y otros órganos, descripta principalmente en pacientes con insuficiencia renal crónica, trasplante renal o disfunción paratiroidea. Hasta la fecha, solo hay siete casos descriptos en la literatura de calcifilaxis que imita arteritis de células gigantes (ACG). En esta revisión presentamos el octavo caso documentado patológicamente.
Calciphylaxis is characterized by intense deposition of calcium in small blood vessels, skin, and other organs, described mainly in patients with chronic renal insufficiency, renal transplant of parathyroid dysfunction. To date, there are only seven cases described in literature of calciphylaxis mimicking giant cell arteritis (GCA). In this review, we present the eighth case pathologically documented.
Subject(s)
Humans , Male , Middle Aged , Temporal Arteries/pathology , Giant Cell Arteritis/diagnosis , Calciphylaxis/diagnosis , Calciphylaxis/pathology , Diagnosis, DifferentialABSTRACT
RESUMEN El síndrome de dedo azul (SDA) se caracteriza por la coloración violácea o azul de uno o más dedos, puede serla primera manifestación de múltiples enfermedades, tanto las que presentan alteraciones directamente en los dedos o ser la expresión de enfermedades sistémicas; los mecanismos fisiopatológicos más comunes son trombosis, embolia, vasoconstricción grave o afección del lecho vascular que puede ser inflamatoria o no inflamatoria. Describimos 5 casos de SDA, donde resaltamos la importancia del diagnóstico temprano y enfatizamos en el concepto de evaluación y abordaje como una urgencia médica, sin importar la causa, ya que su manejo y tratamiento inicial, más el intento de lograr un tratamiento dirigido a una etiología podría disminuir complicaciones irreversibles como la necrosis o amputación.
ABSTRACT Blue finger syndrome (BFS), usually noted by the violet or blue coloration of one or more fingers, may be the first manifestation of several diseases. These may present with alterations directly on the fingers or be the expression of systemic diseases. The most common pathophysiological causes are thrombosis, embolism, severe vasoconstriction, or vasculature involvement that may be inflammatory or non-inflammatory. A description is presented of 5 cases of BFS, where the emphasis is placed on the importance of early diagnosis. The concept of evaluation and approach as a medical emergency is also stressed, because depending on this, it could reduce irreversible complications, such as necrosis and/or amputation.
Subject(s)
Humans , Male , Female , Middle Aged , Aged , Blue Toe Syndrome , Embolism , Vasoconstriction , Early Diagnosis , NecrosisABSTRACT
The human body is unable to synthesize vitamin C and a diet deficient in vitamin C leads to scurvy. Scurvy has become a rare clinical entity in most developed country. However it may still be encountered in selected situation, such as old people live along, young children, food faddists, and alcoholics. Scurvy may mimic other medical conditions such as vasculitis, systemic bleeding disorders, and deep vein thrombosis. For this reason, scorbutic patient are often misdiagnosed or evaluated for other disorder, thus delaying the correct diagnosis. We describe a 63-year-old man who had petechiae and ecchymoses of lower extremity, follicular hyperkeratosis, gingival hemorrhage and corkscrew hairs after consuming a restricted diet for 3 year. The diagnosis was confirmed by low concentration of vitamin C in serum, and treatment with vitamin C leads to a rapid reversal of scorbutc changs. We emphasize the importance of taking into consideration scurvy in the diagnosis of patient presenting with a skin rash resembling vasculitis or systemic bleeding disorder in high risk group.
Subject(s)
Child , Humans , Middle Aged , Alcoholics , Ascorbic Acid , Developed Countries , Diagnosis , Diet , Ecchymosis , Exanthema , Gingival Hemorrhage , Hair , Hemorrhage , Human Body , Lower Extremity , Purpura , Scurvy , Systemic Vasculitis , Vasculitis , Venous ThrombosisABSTRACT
Left atrial myxoma is well-known mimicker of systemic vasculitis. In general, however, these patients showed some symptoms and signs of cardiovascular disease. We experienced a patient with left atrial myxoma who first presented as vasculitis without any symptoms and signs suggesting cardiovascular disorders. A 45 year-old lady showed tender skin nodules, livedo reticuiaris-like skin lesions, severe constitutional symptoms, multiple cerebral infarctions, and elevated ESR and globulin. Skin biopsy findings were thought to be consistent with polyarteritis nodosa. Echocardiography was performed as a routine test for evaluating suspected vasculitis patients and it revealed left atrial myxoma. However, we were not able to detect any auscultation abnormality, even after echocardiography, After echocardiography, we found the tumor emboli in skin biopy specimen with deeper section. This case demonstrated the importance of suspecting the possibility of left atrial myxoma when performing diagnostic work-up for vasculitis.