The Changes of Leukocyte Rheology, Expression of Leukocyte CD18 and the Concentration of Serum Soluble Intercellular Adhesion Molecule-1 in Patients with Psoriasis / 中华皮肤科杂志

Objective To explore the correlation between the leukocyte rheology, cell adhesion molecule(CAM) expression and psoriasis. Methods Enzyme linked immunosorbent assay(ELISA), erythrocyte deformability apparatus and in vitro thrombus and platelet adhesion dual purpose apparatus were used to determine the changes of leukocyte CD18 expression, levels of serum soluble intercelular adhesion molecule 1(sICAM 1), and the changes of leukocyte filtration index(LFI) and leukocyte adhesion rate(LAR). Results The leukocyte CD18 expression, sICAM 1 level, LFI and LAR were significantly increased in patients with psoriasis than those in controls(P