ABSTRACT
El síndrome de Gardner-Diamond o púrpura psicógena es una vasculopatía de presunto origen autoinmune que se caracteriza por una reacción cutánea localizada, asociada a situaciones de estrés emocional. Se presenta el caso de una paciente con lesiones equimóticas, dolorosas y de aparición intermitente, relacionadas con diversos eventos estresores, que habían sido manejadas como manifestación de lupus
Gardner-Diamond syndrome or psychogenic purpura is an vasculopathy characterized by a localized cutaneous reaction, associated with episodes of emotional stress or mental illness as trigger factors. A case of a female patient with multiple, intermittent, nodular, ecchymotic and painful lesions related to various stressing events that was treated as lupus is reported below
Subject(s)
Humans , Lupus Erythematosus, Cutaneous , Diagnosis, DifferentialABSTRACT
Autoerythrocyte sensitization syndrome (AES) was first described by Gardner and Diamond in 1955, when four women with painful bruising were depicted. Patients with AES typically present with the development of recurrent, spontaneous, painful ecchymosis, frequently preceded by a prodrome of pain or itching of the skin. The patients are sensitive to their own red blood cells injected intradermally, and underlying coagulopathies are thought to be absent. We introduce a 70-year-old woman presenting with recurrent episodes of painful bruising on the trunk and extremities.
Subject(s)
Aged , Female , Humans , Diamond , Ecchymosis , Erythrocytes , Extremities , Neurodermatitis , Pruritus , SkinABSTRACT
Se presenta el caso de una mujer de 44 años, blanca, ingresada en el Servicio de Medicina Interna del Hospital Clinicoquirúrgico Docente "Miguel Enríquez" por síndrome febril agudo y hematuria. En el examen físico realizado se notó la salida de lágrimas con sangre muy fluida, por el ángulo externo del ojo izquierdo. La inyección intradérmica en la cara dorsal del muslo derecho de 0,1 mL de sangre autóloga, indujo una reacción equimótica dolorosa en el sitio de la inyección. La inyección de 0,1 mL de solución salina al 0,9 % como control en el muslo contralateral, resultó negativa. Sobre la base del examen clínico y estas pruebas, se concluyó como un Síndrome de Gardner-Diamond. Esta entidad debe ser considerada en el diagnóstico diferencial de un síndrome purpúrico de etiología no bien precisada, fundamentalmente en pacientes con problemas psiquiátricos.
This is the case of a white woman aged 44, admitted in the Internal Medicine Service of "Miguel Enríquez" Clinical Surgical Hospital due to acute febrile syndrome and hematuria. At physical examination performed we noted a very high level of watering with presence of blood by left angle of left eye. The intradermal injection of 0,1 ml of autologous blood in dorsal part of right thigh, induced a painful ecchymotic reaction in injection site. The injection of 0.1 ml of 0,9% saline solution as control in contralateral thigh was negative. On the base of clinical examination and these tests, we conclude that it was a Gardner-Diamond syndrome. This entity must to be considered in differential diagnosis of a purpuric syndrome of a non-well established etiology, mainly in patients presenting with psychiatric disorders.
ABSTRACT
Autoerythrocyte sensitization syndrome (Gardner-Diamond syndrome), also known as painful bruising syndrome or psychogenic purpura, is characterized by sudden and spontaneous painful bruising and swelling on both extremities, and is a psychologically induced painful bruising condition. The exact etiology of the syndrome is an enigma, even today. It occurs primarily in young to middle-aged women who usually have psychogenic disorders. A diagnosis of this syndrome is made on the basis of the clinical history, dermatological examination complemented by a positive autoerythrocyte sensitization test, psychiatric evaluation and the absence of any organic cause. We present a 20-year-old man with characteristic features of this syndrome, who had a positive autoerythrocyte sensitization test. To our knowledge, this is the first case in an adult male reported in the Korean literature.
Subject(s)
Adult , Female , Humans , Male , Young Adult , Complement System Proteins , Diagnosis , Extremities , PurpuraABSTRACT
No abstract available.