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Background: Assessment of disease severity of ulcerative colitis (UC) is crucial for the decision of drug treatment strategy, the appraisal of response to drugs, and the prognosis evaluation. Aims: To establish and validate a discriminant model for the quantification of disease severity of UC. Methods: The clinical data of 169 active UC cases admitted at the Beijing Haidian Hospital were analyzed retrospectively. Based on Truelove-Witts criteria, seven widely accepted indices including temperature, pulse, defecation frequency, hematochezia, hemoglobin (Hb), erythrocyte sedimentation rate (ESR) and albumin (Alb) were selected and a stepwise discriminant analysis was performed to establish a discriminant model using Fisher's linear discriminant function, and then the discriminant model was validated from different aspects. Results: The discriminant model: F1 (mild)=-51.109+0.587X1+0.295X2+0.379X3+0.071X4; F2 (moderate)=-49.905+0.624X1+0.512X2+0.333X3+0.095X4; F3 (severe)=-57.294+0.709X1+0.599X2+0.296X3+0.141X4 [ X1, pulse (beats /min); X2, defecation frequency (times/d); X3, Hb (g/L); X4, ESR (mm/h)]. The result of the newly established discriminant model was moderately correlated with the Truelove-Witts criteria (r
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ObjectiveTo discuss the quantitative criteria of grading nursing of three common psychiatric diseases in psychiatric department. MethodsUsing SI、N-BPRS,BRMS and HAMD scales to evaluate180 patients with schizophrenia,mania and depression upon admission and after admission.The quantitative evaluation of grading nursing of these three diseases was compared. ResultsFor the three common mental diseases N- BPRS scale scores were as follows.Superfine nursing:schizophrenia (80.66+11.22)points; mania (80.05± 15.44)points; depression (76.88±9.82)points.Primary care:schizophrenia (67.47± 10.18)points; mania ( 62.91 ± 10.19 )points; depression ( 56.63±9.52 )points; Secondary nursing:schizophrenia ( 44.04 ±8.67 )points;mania( 39.57±9.47 )points ;depression( 37.73±7.75 )points.The three- level nursing:schizophrenia( 27.97±2.19 )points;mania(27.89±2.28)points;depression(27.45±1.31 )points. ConclusionsUsing evaluating scores of NBPRS scale to determine the quantitative criteria of grading nursing of three common psychiatric diseases is a feasible choice,after training,nurses of high qualification can grasp skillfully the operation process.
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PURPOSE: Film dosimetry as a part of patient specific intensity modulated radiation therapy quality assurance (IMRT QA) was performed to develop a new optimization method of film isocenter offset and to then suggest new quantitative criteria for film dosimetry. MATERIALS AND METHODS: Film dosimetry was performed on 14 IMRT patients with head and neck cancers. An optimization method for obtaining the local minimum was developed to adjust for the error in the film isocenter offset, which is the largest part of the systemic errors. RESULTS: The adjust value of the film isocenter offset under optimization was 1 mm in 12 patients, while only two patients showed 2 mm translation. The means of absolute average dose difference before and after optimization were 2.36 and 1.56%, respectively, and the mean ratios over a 5% tolerance were 9.67 and 2.88%. After optimization, the differences in the dose decreased dramatically. A low dose range cutoff (L-Cutoff) has been suggested for clinical application. New quantitative criteria of a ratio of over a 5%, but less than 10% tolerance, and for an absolute average dose difference less than 3% have been suggested for the verification of film dosimetry. CONCLUSION: The new optimization method was effective in adjusting for the film dosimetry error, and the newly quantitative criteria suggested in this research are believed to be sufficiently accurate and clinically useful.
Subject(s)
Humans , Film Dosimetry , Head , NeckABSTRACT
PURPOSE: Film dosimetry as a part of patient specific intensity modulated radiation therapy quality assurance (IMRT QA) was performed to develop a new optimization method of film isocenter offset and to then suggest new quantitative criteria for film dosimetry. MATERIALS AND METHODS: Film dosimetry was performed on 14 IMRT patients with head and neck cancers. An optimization method for obtaining the local minimum was developed to adjust for the error in the film isocenter offset, which is the largest part of the systemic errors. RESULTS: The adjust value of the film isocenter offset under optimization was 1 mm in 12 patients, while only two patients showed 2 mm translation. The means of absolute average dose difference before and after optimization were 2.36 and 1.56%, respectively, and the mean ratios over a 5% tolerance were 9.67 and 2.88%. After optimization, the differences in the dose decreased dramatically. A low dose range cutoff (L-Cutoff) has been suggested for clinical application. New quantitative criteria of a ratio of over a 5%, but less than 10% tolerance, and for an absolute average dose difference less than 3% have been suggested for the verification of film dosimetry. CONCLUSION: The new optimization method was effective in adjusting for the film dosimetry error, and the newly quantitative criteria suggested in this research are believed to be sufficiently accurate and clinically useful.