A STUDY OF PATIENTS PRESENTING WITH BLUNT ABDOMINAL INJURY WITH SPLENIC TRAUMA AND THEIR OUTCOME.

INTRODUCTION - Spleen injuries are among the most frequent trauma-related injuries. At present, they are classified according to the anatomy of the injury. The optimal treatment strategy, however, should keep into consideration the hemodynamic status, the anatomic derangement, and the associated injuries. The management of splenic trauma patients aims to restore the homeostasis and the normal physiopathology with a multidisciplinary team. Thus, the study to determine the presentation of a patient and further its investigation management and outcome is necessary. OBJECTIVE: To study all the cases (investigation and outcome) of blunt abdominal trauma with splenic laceration with its incidence , mode of presentation, grade, management and factors responsible for morbidity and mortality. MATERIALAND METHODS:Astudy was conducted in our tertiary care hospital on 22 patients presented with blunt abdominal trauma with splenic injury in emergency department during July 2019 to June 2021. RESULTS: In our retrospective study , all the patients underwent primary radiological and pathological investigation with 36% having associated limb injuries (fractures);4.5% with ckd , 9% with thoracic injury, 40% amongst 20-40 age group , 86% being male, 59.5% resulted from RTA, 31.5 % resulted from fall from height,0% with assault, 4.5% along with head injury, 9% with associated rib fracture,0% patient with free gas under diaphragm ; 9% with grade 1, 22% with grade 2, 31.5% grade 3 , 13.5% grade 4, 22%grade 5 splenic injuries. 91% patients underwent splenectomy and were given vaccination 15 days post operatively against capsulated organisms.9% patients were managed conservatively. Patients were followed up for 6 months postoperatively with 4.5% mortality rate. CONCLUSION: Splenic injury is most common solid organ injury in blunt abdominal trauma in 20- 40 years age group majority male and results maximally by RTA; associated with limb fractures commonly with liver as associated solid organ injured. Aggressive resuscitation and emergency laparotomy (splenectomy) yields excellent outcome

A prospective study of injury pattern and outcome of blunt trauma abdomen patients in a tertiary care hospital in eastern part of India

Background: Abdominal trauma continues to account for a large number of trauma-related injuries and deaths. The evaluation and treatment of abdominal injuries are critical components in the management of severely injured trauma patients. The study was done to study pattern and outcome of BTA patients in a tertiary care hospital in eastern part of India as few studies exist in this part of the country.Methods: Prospective descriptive study conducted in in SRN Hospital, Prayagraj over a period of one year with all cases of blunt injury abdomen included with respect to inclusion criteria.Results: In our study mean age was 23.2±17.6 years. 92% were male and 8% were female RTA are responsible for most number of cases (78%). Conservative management done in 34 (68.0%) and Operative Intervention done in 16 (32.0%) cases. In our study, X-ray erect had 75% accuracy total subsets of 336 organ scans were performed on ultrasound specific injury was seen in total 50 cases and total 210 CT scans performed was able to pick up 59 injuries (p=0.0002). CECT forms the core investigation of choice in dealing with blunt injury abdomen cases. In our present study, paralytic ileus (prolonged) (31%) and pelvic intraabdominal abscess (31%) as postoperative complications.Conclusions: CECT abdomen is the investigation of the choice with RTA being the most common mode of BTA. So effort should be made to implement traffic rules. Hemodynamic instability with radiological findings useful in deciding operative versus conservative management of blunt trauma patients.

Outcomes of Surgical Management of Floating Knee Injuries

Introduction: Floating knee, referred to as ipsilateralfractures of the femur and tibia, is usually associated withseveral complications and mortality. This study was designedto present our experience with treatment of this injury.Demographic parameters like age, sex, mechanism of injury,associated injuries, method and results of treatment, andcomplications of floating knee are discussedMaterial and Methods: This Prospective study wasperformed between January 2014-July 2016. All patientswith floating knee injuries who were admitted to the PMCHfulfilling the inclusion and exclusion criteria were included.The information about the 20 cases of floating knee injurieswere gathered, particularly the demographic parameters, modeof injury, bones involved, condition of skin, other associatedinjuries and their neurovascular status. The patients werefollowed for a minimum of one year duration and functionaloutcome was assessed.Result: Most of the patients were between 21-30years of age(45%). The floating knee injuries were more common in males(85%). FraserType I fracture was observed in 70% of cases.Roadtraffic accidents(RTA) was the most common cause ofsuch injuries. 18 out of 20(90%) cases were having associatedinjuries while only 10%were cases of isolated floating knee.The most common early and late complications were infectionand knee stiffness respectively. The final outcome as perKarlstrom criteria was excellent and good in 11 out of 14 casesof Fraser type I fracture and in 3 out of 6 cases of Fraser type IIfracture, and this was statistically significant (P=0.05).Conclusion: This study revealed that the complication rateassociated with floating knee injuries remain high and theprognosis mostly depends on type of injury and associatedinjuries. This study also advocates early aggressive approachfor management of these injuries.

Operative Management of Calcaneal Fractures using Mippo Technique

Introduction: Calcaneal fractures continues to be a topic ofcontroversy in terms of the optimal management modality.Current study aimed to access the sinus tarsi approach forthe fixation of calcaneal fractures in terms of radiological andfunctional results.Material and Methods: Study was conducted on 30 patientsof both genders aged between 20 and 60 years with both jointdepression and tongue type fractures, Sanders type 2 and type3 fractures.Results: In our study, as per AOFAS Scale at 3 months, 19(63.33%) calcaneum cases fell into the excellent group, 9 (30%)into good and 2(6.66%) into poor result group. The Mean ±SDAOFAS scale was 78.43±7.17 (range 55-85). At 6 months, theresult as per AOFAS scale showed further improvement with 28(93.33%) calcaneum cases falling into the excellent group and 2(6.66%) falling into the good result group. None of them fell inpoor group at 6 months follow up. The Mean ±SD AOFAS scalewas 90.03±5.24 (range 74-95).Conclusion: Fixation with plate using MIPPO techniquethrough sinus tarsi approach is an effective and safe methodwith good clinical and radiological results, for the treatmentof calcaneal fractures; to achieve anatomical restoration undervision, stable fixation and early mobilization with minimal softtissue complications.

Pattern and management of penetrating and nonpenetrating thoracic injuries

Background: Chest trauma constitutes a major public health problem which  includes the injuries to chest wall, pleura, tracheobronchial tree, lungs, diaphragm, oesophagus, heart and great vessels. It consist of more than ten percent of all traumas and twenty five percent of death due to trauma occurs because of chest injury. Chest trauma is increasing in frequency in urban hospitals. Penetrating and nonpenetrating thoracic injuries the most serious injuries leading to significant morbidity and mortality.Methods: This study was prospective observational study of 220 patients of thoracic trauma both penetrating and non-penetrating. These patients admitted in general surgical units from August 2017 to May 2018  of Pandit Bhagwat Dayal  Sharma,  PGIMS  Rohtak Haryana India. The study was pertaining to both penetrating  and non-penetrating chest trauma.Results: Out of 220 chest injury patients who were studied during the said period, Males were 203 and females 17 by a ratio of 12:1 and age ranged from lowest 18 years to 85 years of age. Majority of the patients (90.45%) sustained blunt injuries. RTA was the common mechanism of blunt injury affecting (50.45%) of patients. Multiple Rib fractures was the commonest type of chest injury (21.36%) followed by head injury (17.27%). Head injury was the commonest associated injury seen in our patients. Conclusions: Chest trauma resulting from road traffic accident remains a major mechanism of chest injury. The  measures to decrease the trauma are, educating people about traffic rules and regulations and strictly implementing them is necessary to reduce incidence of chest injuries.

The Study on Pattern of External Injuries During Road Traffic Accidents of Helmeted and Non Helmeted Victims at Tertiary Care Centre

Background: Motor Vehicle crashes are a remarkable reasonfor casualty all over throughout the world. By 2020, enginevehicle damage is predictable to wind up noticeably the thirddriving supporter of the international weight of illness on theglobe.Methods: The study was conducted for the period of one yearand One hundred subjects were studied at Department ofForensic Medicine &Toxicology S.N. Medical College Jodhpur.Subsequent information was collected from the study: Type ofInjuries (Grievous or Non grievous), Alcohol intake present orabsent, Number of Abrasions/ Bruises/Lacerations andGlasgow Coma Scale. Data was collected and tabulated.Statistical analysis was done. For quantitative data ‘t’ test wasused and for qualitative chi-square test was used. The ‘p’ value<0.05 is considered as statistically significant.Results: Out of total 100 patients, 55 helmeted and 35 nonhelmeted individuals, 22 and 23 persons sustained grievousinjuries respectively. In case of helmeted individuals, thepresence and absence of alcohol intake was observed in 26and 29 cases respectively. Out of 55 helmeted persons 54persons sustained abrasions, 39 had bruises and 17individuals had lacerations. The Glasgow Coma Scale (GCS)score between 3-7 and 8-15 of helmeted individuals were 20%and 80% of the individuals respectively.Conclusions: Serious injury has been found more in nonhelmeted individuals in comparison to helmeted individuals.Alcohol intake has been found more in helmeted individuals incomparison to non-helmeted individuals. The most commoninjury in helmeted individuals has been found to be abrasion.Lacerations have been found more in non-helmetedindividuals. GCS of less than 7 was found to be in more in nonhelmeted individuals in comparison to the helmeted individuals

Identification of a novel entecavir-resistant mutation rtL180M+A186T+M204V of hepatitis B virus / 解放军医学杂志

Objective To identify whether rtL180M+A186T+M204V mutation is a novel entecavir (ETV)-resistant mutation. Methods A total of 12 708 patients in the Fifth Medical Center of Chinese PLA General Hospital from July 2011 to July 2016 were enrolled in this study. Drug resistance mutation in reverse transcriptase region (RT) were analyzed by direct sequencing and verified by clonal sequencing if rtL180M+A186T+M204V has been detected (≥20 clones/sample); 1.1-mer HBV replicons harboring wild-type or mutant RT gene were constructed respectively and transfected into HepG2 cells for phenotypic analysis. Results ETV experienced patients were detected in 4047 of total patients. Among these patients, classical ETV-resistant mutation of HBV and rtL180M+A186T+M204V mutation were detected in 795(19.64%) and 7(0.17%), respectively. The rtL180M+A186T+M204V mutant was consistent with the features of ETV-resistant mutation: all the rtA186T-positive patients had a history of lamivudine exposure prior to ETV treatment; the emergence of the mutations was associated with virological breakthrough or inadequate virological response to ETV; phenotypic analysis showed that patient-derived rtL180M+A186T+M204V mutant exhibited 13.3% replication capacity and 210.2-fold decreased susceptibility to ETV compared to the wild-type strain, while the mutant remained sensitive to tenofovir (TDF). Conclusions rtL180M+A186T+M204V as a novel ETV-resistance mutation has a low clinical detection rate, which is related to the markedly reduced replication capacity of the mutant. TDF-based rescue therapy should be considered for patients harboring rtL180M+A186T+M204V mutation in clinical practice.

Effect and related mechanisms of RTA-408 on rat vascular smooth muscle cell calcification induced by advanced glycation end products / 中华心血管病杂志

Objective@#To investigate the effect and related mechanisms of RTA-408 on rat vascular smooth muscle cells (VSMCs) calcification induced by advanced glycation end products(AGE).@*Methods@#VSMCs were isolated from the aorta of Sprague Dawley rats and cultured in vitro. The fifth generation of VSMCs were randomly divided into 4 groups with random number table including control group(cells were incubated with normal medium for 2 days, then incubated with bovine serum albumin for 5 days),AGE group (cells were incubated with normal medium for 2 days, then incubated with 200 mg/L AGE for 5 days), experimental group(cells were incubated with 100 nmol/L RTA-408 for 2 days,then incubated with 200 mg/L AGE for 5 days),and RTA group(cells were incubated with 100 nmol/L RTA-408 for 2 days,then incubated with bovine serum albumin for 5 days). Cytosolic calciumin VSMC was measured using arsenazo Ⅲ assay. Von Kossa staining was utilized to detect the calcium deposition.The contents of malondialdehyde(MDA) and superoxide dismutase(SOD) in VSMCs were tested by appropriate kits.The protein expressions of osteopontin (OPN), alkaline phosphatase (ALP), nuclear factor E2 related factor 2(Nrf2), and NAD(P)H: quinone oxidoreductase 1(NQO1) were examined using Western blot.@*Results@#(1) Cytosolic calciumconcentration was significantly higher in AGE group than in control group((2.43±0.15) mmol/L vs. (1.23±0.09) mmol/L, P<0.01), which was significantly reduced in experimental group((1.62±0.18) mmol/L,P<0.01 vs. AGE group). (2) Calcium deposition in VSMCs was significantly upregulated in AGE group than in control group(3.64±0.50 vs. 1.00±0.12, P<0.01), and was downregulated in experimental group (1.56±0.37, P<0.01 vs. AGE group). (3) The MDA contents were higher((3.79±0.27) nmol/mg prot vs.(1.99±0.15) nmol/mg prot, P<0.01), while the SOD activities were lower((308.45±14.28) U/mg prot vs. (428.58±11.00) U/mg prot, P<0.01) in AGE group than in control group. The MDA contents were lower((2.37±0.19) nmol/mg prot vs. (3.79±0.27) nmol/mg prot, P<0.01),while the SOD activities were higher((391.03±22.92) U/mg prot vs. (308.45±14.28) U/mg prot, P<0.05)in experimental group compared with AGE group. (4) The relative expressions of OPN and ALP were higher in AGE group than in control group(3.06±0.21 vs. 1.00±0.07, and 2.89±0.29 vs. 1.00±0.10,both P<0.01), both (OPN(1.15±0.12) and ALP(1.45±0.15)) were downregulated in experimental group (both P<0.01 vs. AGE group). (5) The relative protein expressions of Nrf2 and NQO1 in experimental group were higher than AGE group(2.37±0.17 vs. 1.17±0.09, and 3.91±0.18 vs. 1.05±0.08, both P<0.01).@*Conclusion@#Activation of nrf2/NQO1 signaling pathway by RTA-408 can reduce the AGE-induced VSMC calcification through attenuating oxidative injury.

Bilateral Proximal Femur Fractures in a Patient with Renal Tubular Acidosis: A Case Report

@#The diagnosis of pathological fractures is on the rise. Themorbidity involved does not only burden the patient and theirfamilies but it has a great toll on the healthcare system aswell. Early identification of the patient at risk is aninvaluable tool to cut cost and improve the patient’s qualityof life. Multiple renal pathologies have been highlighted inrelation to the risk of pathological fractures; however,complications in renal tubular acidosis have been rarelydocumented. Nevertheless, prompt action with adequate andrelevant patient education ultimately can reduce theassociated morbidity. We present a case of poor control ofthe disease and its debilitating pathological fracturecomplications.

Clinical value of Rta protein antibody IgG of EB virus in diagnosis for nasopharynx cancer / 国际检验医学杂志

Objective To evaluate the clinical value of Rta protein antibody IgG of EB virus(Rta/IgG)in the diagnosis of naso‐pharyngeal carcinoma patients in Zhuhai .Methods A total of 75 patients with nasopharyngeal cancer diagnosed by histopathologi‐cal detection without therapy were recruited into nasopharyngeal cancer group ,100 healthy persons were selected into control group ,there were 19 patients in liver cancer ,gastric cancer ,lung cancer ,lymphoma group and cervical cancer group .Rta/IgG and EB virus antibody of shell (VCA/IgA) were detected by enzyme‐linked immunosorbent assay .Results The positive rate of Rta/IgG in the nasopharyngeal cancer group was significant higher than those of liver cancer ,gastric cancer ,lung cancer ,lymphoma group and cervical cancer and control group(P0 .05) .The sensitivity rates of Rta/IgG single detection ,VCA/IgA single detection ,com‐bined detection of Rta/IgG and VCA/IgA were 81 .3% ,89 .3% ,94 .6% respectively ,while the specificity rates were 93 .0% ,84 . 0% ,80 .0% respectively .Conclusion Rta/IgG is a sensitive and specific serologic parameter for nasopharynx cancer diagnosis ,but it is not a proper maker for evaluating clinical stage of nasopharynx cancer .The combined detection of Rta/IgG and VCA/IgA could improve the diagnosis rate of nasopharyngeal carcinoma in Zhuhai .

Patterns of Injuries in Road Traffic Accidents in a Rural Tertiary Hospital.

Road traffic injuries are a major but neglected global public health problem, requiring concerted efforts for effective and sustainable prevention. Of all the systems that people have to deal with on a daily basis, road transport is the most complex and the most dangerous. Objectives: To study the patterns of injuries in the road traffic accidents and days of hospitalization. Materials and Methodology: The study was retrospective record based study and included cases reported and recorded from October 2007 to March 2008. Results: The present study was designed to study the patterns of injuries in RTA (Road Traffic Accidents) in Anand district of Gujarat. The results showed that out of total 423 RTA cases, 327(77.3%) of the victims were males and the rest 96(22.7%) were females. Two wheeler riders and pedestrians form twothird of the total victims. Total 232 fractures were noticed and of these maximum numbers occurred in the lower limb region (53.86%) followed by fractures in the upper limb (24.54%) and 10.77% fractures were in the skull. Abrasions were seen most commonly on lower limbs (34.31%), lacerations were seen mostly on head (41.07%) and internal injuries were noticed more in the head region (31.48%). 74.2% of the victims were hospitalized and the rest 25.8% took treatment at the trauma centre. 51.1% of RTA victims were hospitalized for 1-5 days while patients who did not require hospitalization were 109(25.8%).

Study of pattern of fatal head injury cases due to road traffic accidents in Bhavnagar Region, Gujarat.

Introduction: Head injury is an important cause of mortality world wide as head is the most vulnerable part of the body involved in fatal road traffic accident. Material and Methods: The present study was under taken on 117 victims of road traffic accident who died due to injuries sustained on the head, which were autopsied at mortuary complex of Government Medical College and Sir Takhtsinhji General Hospital, Bhavnagar, Gujarat over a period of 1 year between 1st January 2011 to 31st December 2011. Observation: Most of the road traffic accident had taken place in the afternoon hours (12.01 P.M. to 6.00 P.M.).Majority of victims were found in age group of 21 to 30 years. Two wheeler occupants were the most commonly involved. Four wheeler occupants and pedestrians were least commonly involved. A large proportion of the victims died within 0 to 12 hours of the accident. Conclusion: Very high morbidity at place of accident or at initial phase of treatment is definitely alarming and highlights the need for taking urgent steps for establishing good pre-hospital care and provision of trauma services at site.

Hypokalemic Periodic Paralysis and Distal Renal Tubular Acidosis Associated with Renal Morphological Changes.

We report an unusual case of 5-yrs-old girl presenting with recurrent episodic weakness with documented hypokalemia, polyuria and failure to thrive. The child was finally diagnosed as having distal renal tubular acidosis. Imaging studies revealed associated hypoechoic spaces in renal medulla. Long term treatment with alkali and maintenance of normokalemia lead to regression of these morphological changes

Electrolyte Imbalances and Nephrocalcinosis in Acute Phosphate Poisoning on Chronic Type 1 Renal Tubular Acidosis due to Sjogren's Syndrome

Although renal calcium crystal deposits (nephrocalcinosis) may occur in acute phosphate poisoning as well as type 1 renal tubular acidosis (RTA), hyperphosphatemic hypocalcemia is common in the former while normocalcemic hypokalemia is typical in the latter. Here, as a unique coexistence of these two seperated clinical entities, we report a 30-yr-old woman presenting with carpal spasm related to hypocalcemia (ionized calcium of 1.90 mM/L) due to acute phosphate poisoning after oral sodium phosphate bowel preparation, which resolved rapidly after calcium gluconate intravenously. Subsequently, type 1 RTA due to Sjogren's syndrome was unveiled by sustained hypokalemia (3.3 to 3.4 mEq/L), persistent alkaline urine pH (> 6.0) despite metabolic acidosis, and medullary nephrocalcinosis. Through this case report, the differential points of nephrocalcinosis and electrolyte imbalances between them are discussed, and focused more on diagnostic tests and managements of type 1 RTA.

Effect of Pinus massoniana Lamb. bark extract on lytic cycle of Epstein-Barr virus.

Pinus massoniana bark extract (PMBE) at a concentration of 60 μg/mL or more inhibits the expression of Epstein–Barr virus (EBV) lytic proteins, such as Rta, Zta, and EA-D. EBV lytic cycle was blocked by inhibiting the transcription of immediate-early genes. The results suggest that the PMBE has anti-EBV activity. Thus, the extract is potentially useful in preventing the lytic development of EBV in vitro.

Road Traffic Accidents by 'Nasimon' and 'Karimon'-A Study in Faridpur Medical College Hospital.

Road traffic accidents in Bangladesh have been rapidly increasing with huge mortality through road accidents each year. There are many causes of road accidents in recent years; one important cause is running of locally made improvised three wheelers (flat bed tricycle) in the urban areas and also on the highways, popularly known as 'Nasimon' and 'Karimon'. This prospective study was carried out in Faridpur Medical College Hospital from January through June 2011, to study the accident patients caused by 'Nasimon' and 'Karimon'. Fifty six (12%) patients were of RTA by 'Nasimon' and 'Karimon' out of a total of 468 patients admitted into our hospital during this period. Most patients (41, 73.21%) were male, highest accidents (24, 42.86%) were observed among 21-30 years age group and most victims (33, 58.93%) were belonged to low socioeconomic status. Commonest (31, 55.36%) victims were passengers of 'Nasimon' and 'Karimon' while maximum number of accidents (46, 82.14%) took place in the urban areas and on the highways. Injury pattern of victims were similar to that found in any other road accident patients. These three wheelers 'Nasimon' and 'Karimon' are run in violating of Bangladesh Motor Vehicles Act (1983) as they are totally unfit for plying on the highways. Strict surveillance against these illegal and risky vehicles on the highways and in the urban areas by law enforcing agencies is required as a measure to reduce the burden of road accidents in our country.

An epidemiological survey of fatal road traffic accidents and their relationship with head injuries.

Death from road traffic accidents (RTA) and in particular Motor vehicle Traffic Accidents have been characterized worldwide as a hidden epidemic which affects all sectors of society. It account for 2.1% of global mortality. A retrospective study of fatal cases of RTA was conducted at Department of Forensic Medicine and Toxicology, Jawaharlal Nehru Medical College, Belgaum, Karnataka, India between 1-1-2004 to 31-12-2009. The majority of victims belonged to the age group 31-40 years (145 cases; 28.7%). Female were less involved than men with ratio of 1: 3.3. In our present study total vehicular accident fatalities comprised 506 (48.7 %) out of total 1039 medico legal cases autopsied during five years (2005 to 2009). Our study shows the overwhelming majority of the deceased (76.9%) were males. This study shows that most of the deaths in road traffic accidents, take place either within 24 hours or on the spot of injury which is very alarming and highlights the need for taking urgent steps for establishing good pre-hospital care and provision of trauma services at site in India.

Study of road traffic accidental deaths (RTA) in and around Bastar Region of Chhattisgarh.

To analyze the magnitude of head injury in fatal RTA cases, present study was conducted in the department of Forensic Medicine Toxicology, Govt. Medical College, Jagdalpur (Chhattisgarh) in 2009 calendar year. The present study was undertaken on 105 victims of RTA who died due to head injuries, which autopsied at GMC, Jagdalpur (C.G). Most of the accidents occurred in the afternoon hours (12: 01 - 18:00). There was a clear male dominance (88.57%). The most affected age was middle age (21-40 yrs) & most commonly affected age group is 21-30 yrs. Vehicular occupants were commonly affected (63.80%) & amongst them two wheeler occupants most commonly involved. Fissure fracture of the skull was commonest (45.71%) & parietal region of head was mostly involved region of the head (27.61%). Among the intracranial hemorrhages, subdural hemorrhage (SDH) was commonest (31.42%). In relation duration of survival time 59.04% of victims died within 24 hrs of fatal accident.

Profile of road traffic accidents & head injury in Jaipur (Rajasthan).

The injuries and death due to head trauma are inescapable in the modern way of life and their correct interpretation is vital to the reconstruction of the events of Forensic Medicine and their proper management for treatment of the injured. The present study was conducted in the department of forensic medicine, SMS medical college, Jaipur in year 2003-2004 to analyze the quantity of the magnitude of deaths due to Road Traffic Accidents (RTAs) and to provide epidemiological data, so the preventive measures can be undertaken. Our study shows that majority of the victims of RTA were male of middle age group (20-40 years), when they were going on two wheelers with out wearing helmets.

Fracture of the temporal bone: A tomographic v/s autopsy study.

The present study was conducted in the Dep’t. of Forensic Medicine & Toxicology, SMS Medical College Jaipur (Raj), in the period from 15 Dec. 2001 to 4 April 2002. With the aim to find out the correlation of X-ray (Skull), CT scan (Head), Surgical intervention findings with the autopsy findings in the cases of acute Head trauma. Total of 140 cases of acute head trauma were selected irrespective of age, sex, religion caste etc. who had been admitted in Neurosurgery dep’t. And X-ray, CT scan head and /or surgical intervention had been done, subsequently died & autopsy was performed. X- ray skull gave batter information on fracture of skull than CT Scan, particularly when the fracture is located on the vault or base of skull and is of linear variety [1]. 27 cases of fracture of the temporal bone were specially studied, out of these 140 cases. All these cases had the features of triad, indicating of fracture of petrous part of temporal bone i.e. CSF Otorrhoea 14(51.1%), 7th nerve palsy 9(33.3%), serve middle ear bleeding 18(66.6%) & conducting hearing loss 5(85%). The plain X-ray demonstrated the fracture of temporal bone in 21 cases (79%) and the CT Scan demonstrated their in 24 cases (88%) Longitudinal fractures are common in 18 cases (66%) and procedure of choice for their demonstration is lateral tomography, Transverse fracture alone was uncommon (2 cases) and can only be demonstrated in anterior posterior tomographic projections and is usually associated with occipital fractures. CT Scan Examination give better information in detection of fracture of temporal bone as well as the type of fracture [2] which is essential for planning the surgical intervention or treating the patient conservatively in order to avoid the complications like, persistent CSF otorrhoea, posterior meningitis or even death.