ABSTRACT
Brain glioma is the most common primary nervous system tumors,in which high-grade glioma grows rapidly,often infiltrates growth,and easy recurrence after treatment. Its mortality and morbidity are still high. Surgical resection is the preferred treatment for high-grade glioma. Postoperative radiotherapy is one of the-important adjuvant therapy. At present,tumor radiotherapy was guided the sketch of the target area by MRI ima-ges,but MRI imaging has limitations. With the development and application of a variety of radioactive tracers,PET reflects the extent of tumor infiltration through the metabolic changes of tumor tissue,and also helps to identify ra-dioactive necrosis and tumor recurrence. The combination of PET/MRI has a good prospect in the radiotherapy of high-grade glioma.